Image_1_Stimulation of the Epithelial Na+ Channel in Renal Principal Cells by Gs-Coupled Designer Receptors Exclusively Activated by Designer Drugs.TIF by Antonio G. Soares (11328795)

“…The Gs-adenylyl cyclase-cAMP signal transduction pathway is believed to play a central role in the normal control of ENaC activity in PCs. …”

<b>Study of the best prediction model for the effectiveness of subcutaneous immunotherapy in childhood asthma patients</b> by Qiuyan Yang (14760943)

“…<p dir="ltr"><b>Objective:</b> To explore the best prediction model for the effectiveness of subcutaneous specific immunotherapy (SCIT) and the best time to achieve good disease control. <b>Methods: </b>A total of 141 children aged 5-14 years were diagnosed with allergic asthma with or without allergic rhinitis from January 2008 to June 2023. …”

Bcl-xL siRNA effectively knocks down Bcl-xL mRNA and protein and induces platelet apoptosis. by Shifang Yu (721211)

“…Bcl-xL expression and apoptosis were assessed 48 h after transfection. (<b>a</b>) Expression levels of the Bcl-xL mRNA were assessed by qRT-PCR. 5s rRNA was used as an endogenous control. …”

Table_2_Stimulation of the Epithelial Na+ Channel in Renal Principal Cells by Gs-Coupled Designer Receptors Exclusively Activated by Designer Drugs.DOCX by Antonio G. Soares (11328795)

“…The Gs-adenylyl cyclase-cAMP signal transduction pathway is believed to play a central role in the normal control of ENaC activity in PCs. …”

Mitochondrial genome-encoded long noncoding RNA and mitochondrial stability in diabetic retinopathy by Jay Kumar (10445417)

“…Retinal microvessels from streptozotocin-induced diabetic mice and human donors with diabetic retinopathy presented similar decrease in Lnc<em>CytB</em> and mtDNA nucleoids. Thus, Lnc<em>CytB</em> has a major role in maintaining mitochondrial genomic stability, and its downregulation in hyperglycemic milieu contributes to increased vulnerability of mtDNA to damage.…”

Table_1_Stimulation of the Epithelial Na+ Channel in Renal Principal Cells by Gs-Coupled Designer Receptors Exclusively Activated by Designer Drugs.DOCX by Antonio G. Soares (11328795)

“…The Gs-adenylyl cyclase-cAMP signal transduction pathway is believed to play a central role in the normal control of ENaC activity in PCs. …”

Table_1_Stimulation of the Epithelial Na+ Channel in Renal Principal Cells by Gs-Coupled Designer Receptors Exclusively Activated by Designer Drugs.DOCX by Antonio G. Soares (11328795)

“…The Gs-adenylyl cyclase-cAMP signal transduction pathway is believed to play a central role in the normal control of ENaC activity in PCs. …”

Table_2_Stimulation of the Epithelial Na+ Channel in Renal Principal Cells by Gs-Coupled Designer Receptors Exclusively Activated by Designer Drugs.DOCX by Antonio G. Soares (11328795)

“…The Gs-adenylyl cyclase-cAMP signal transduction pathway is believed to play a central role in the normal control of ENaC activity in PCs. …”

QRT-PCR for 27-hydroxylase and ABCA1 message in NS398-treated THP-1 macrophages exposed to prostaglandins or TXA by Edwin SL Chan (28334)

“…THP-1 human macrophages were exposed to the following conditions represented by the five bars (from left to right): (1) RPMI 1640, (2) NS398 (50 μM), (3) PGE(0.1 μM) + NS398 (50 μM), (4) PGD(14 μM) + NS398 (50 μM), and (5) TXA(3 μM) + NS398 (50 μM) (24-hour exposures to NS398 alone followed by addition of indicated PG or TXAfor a further 24 hours). …”

<i>H. influenzae</i> clinical isolates self-aggregation. by Junkal Garmendia (217415)

“…NTHi1a-1c self-aggregated significantly slower than NTHi2a-2b (p<0.0001 at 1 h; p<0.001 at 1.5 h). …”

Increased secretion of cystatin in response to exercise is transient. by Marcelo de Lima Sant’Anna (7542707)

“…Sprints at 65%, 75% and 85% following first sample are shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0224147#pone.0224147.g004" target="_blank">Fig 4</a>. # indicates a significant increase compared to total protein at rest (<i>pre</i>)(p = 0.012, n = 12). * indicates a significant increase of type-S cystatin at 5 min and § a significant decrease at 10 min compared to resting value (p = 0.012, n = 12). …”

Knockdown of α-actinin-2 prevents spine maturation in response to NMDA receptor activation. by Jennifer L. Hodges (207936)

“…<p><b>A)</b> When α-actinin-2 is knocked down, spines do not shorten or assume a “mushroom” morphology in response to glycine. …”

Table 1_In Vitro biomechanical study of meniscal properties in patients with severe knee osteoarthritis.xlsx by Yuqi Liu (501183)

“…Both tensile and compressive moduli exhibited a stepwise decrease with increasing degeneration. …”

Table 2_In Vitro biomechanical study of meniscal properties in patients with severe knee osteoarthritis.xlsx by Yuqi Liu (501183)

“…Both tensile and compressive moduli exhibited a stepwise decrease with increasing degeneration. …”

Effects of PD-0332991 on BSG cell lines derived from genetically engineered mouse models. by Kelly L. Barton (465812)

“…<p>Cells were treated with PD-0332991 for 48 hours before being harvested for MTT or BrdU assays to assess cell survival and proliferation, respectively. (A) MTT assays (left panel) show minimal cytotoxic activity at doses up to 5µM in cell lines derived from PDGF-B; Ink4a-ARF deficient BSGs. …”

Deletion of <i>Wwox</i> results in defective mammary branching and lobuloalveolar development. by Brent W. Ferguson (167494)

“…<p>(A–B) Representative microphotographs obtained from whole mounts of 12 week virgin <i>BK5 Wwox WT</i> (A) and <i>KO</i> (B) mammary glands. …”

The Red Imported Fire Ant (<i>Solenopsis invicta</i> Buren) Kept Y not F: Predicted sNPY Endogenous Ligands Deorphanize the Short NPF (sNPF) Receptor by Prati Bajracharya (643415)

“…Receptor deorphanization is an important step to understand the neuropeptide receptor downstream signaling cascade. …”

Structural, wear and thermal behaviour of Cu–Al2O3–graphite hybrid metal matrix composites by Mittal, P.

“…Copper matrix composites with Al2O3–graphite reinforcement (0.5-0.5, 1.0-1.0, 1.5-1.5 and 2.0-2.0 wt%) were prepared by stir casting process. …”
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Cleavage of BID, loss of MMP, change in expression of anti- and pro-apoptotic proteins. by Radha Pujari (484718)

“…<p>(A) Molt-4 cells were treated with RBL (5 µg/ml) for different time periods and the effect on 21kDa uncleaved Bid was studied by western blot analysis. …”

ICC results of Elk1 and Elk1-3R effects on endogenous katanin-p60 level. by Dolunay Kelle (6388055)

“…(B) Relative fluorescence density graph shows that the expression of katanin-p60 was 5.5 fold decreased in Elk1 overexpressed cells compared to control cells. …”