Downregulation of COP9 signalosome subunits differentially affects the CSN complex and target protein stability-3 by Andreas Peth (85734)

“…The autoradiography shows phosphorylation of CSN2 and CSN7 in the precipitate from siGFP as well as siCSN5 cells. Although same numbers of cells were used and the amount of the CSN complex is almost identical in control and siCSN cells, there was a slight increase of CSN2 and a decrease of CSN7 and overall phosphorylation with the CSN from siCSN5 cells. …”

Persistent combinatorial Laplacian matrixes for Dowker complex from C-C pair of PDBID 2POG. by Xiang Liu (119470)

“…The cutoff extracting the binding core region is 5Å, filtration values are 3.5Å, 4Å, 4.2Å, 4.5Å and 5Å. …”

Predicting alternans in the Ca²⁺-driven model with positive Ca²⁺ to APD coupling during ramp pacing. by Mathieu Lemay (330649)

“…<i>Right</i>: using a SD of BCL of 5 ms, after adding a Gaussian error on APD (SD = 1 ms; windows of 150 cycles). …”

Data_Sheet_1_Genotypic Variation in Cultivated and Wild Sorghum Genotypes in Response to Striga hermonthica Infestation.zip by Nicoleta Muchira (11095392)

“…This study was undertaken with the aim of identifying new sources of resistance to Striga in comparison with the conventional sources as standard checks. We evaluated 64 sorghum genotypes consisting of wild relatives, landraces, improved varieties, and fourth filial generation (F₄) progenies in both a field trial and a pot trial. …”

Genes associated with MNase-sensitivity. by Motomasa Ihara (561771)

“…All Parg/Wt, All PJ34/Wt: comparison of all <i>Parg</i>(110)^−/− males (n = 10) with wild-type (n = 9) males or males treated with PJ34 (n = 4) with wild-type control males (n = 9).…”

image_2.tif by Katrin Zlabinger (4498639)

“…Here, we investigated the effect of decreased AMF on oxidative stress marker matrix metalloproteinase-2 (MMP-2) and its influence on the fate and homing and paracrine character of MSCs after IC or intramyocardial cell delivery in a closed-chest reperfused myocardial infarction (MI) model in pigs.…”

image_1.tif by Katrin Zlabinger (4498639)

“…Here, we investigated the effect of decreased AMF on oxidative stress marker matrix metalloproteinase-2 (MMP-2) and its influence on the fate and homing and paracrine character of MSCs after IC or intramyocardial cell delivery in a closed-chest reperfused myocardial infarction (MI) model in pigs.…”

image_3.tif by Katrin Zlabinger (4498639)

“…Here, we investigated the effect of decreased AMF on oxidative stress marker matrix metalloproteinase-2 (MMP-2) and its influence on the fate and homing and paracrine character of MSCs after IC or intramyocardial cell delivery in a closed-chest reperfused myocardial infarction (MI) model in pigs.…”

EEG delta power in NREM sleep after SD is associated with <i>Kif16b</i> and <i>Wrn</i>. by Shanaz Diessler (5617589)

“…For the δ1 increase after SD, we obtained a suggestive QTL on chromosome 8 and a significant prioritization score for the DNA-helicase <i>Wrn</i>. …”

Validation of microarray results by qRT-PCR for 7 genes located within SPI-2. by Hyunjin Yoon (29786)

“…The results show that mutations in 6 regulators (<i>himD</i>, <i>phoP</i>/<i>phoQ</i>, <i>ssrA</i>/<i>ssrB</i>, <i>slyA</i>, <i>csrA</i>, and <i>ompR</i>/<i>envZ</i>) strongly decrease expression of SPI-2, in 5 strains there is a significant decrease (<i>hnr</i>, <i>rpoE</i>, <i>smpB</i>, <i>crp</i>, <i>hfq</i>) while in the remaining 3 no decrease or even an increase is observed for <i>fruR</i> (the others showing no change are <i>spvR</i> and <i>rpoS</i>).…”

Expression of hereditary hemochromatosis C282Y HFE protein in HEK293 cells activates specific endoplasmic reticulum stress responses-2 by Matthew W Lawless (75792)

“…</p><p></p>r luciferase reporter gene vector (-luc) with or without pZeoSv2(data not shown), pMA1AT, or pZA1AT. As positive control or treatment, five hours post transfection cells were incubated with 2.5 μM thapsigargin or 300 μM TUDCA acid for 24 h. …”

Inhibition of TPA-induced ERK activation partially restores chemotherapy-induced Mcl-1 degradation and cell death. by Shanna K. Nifoussi (128297)

“…The blot shown is representative of 3 independent experiments, where similar effects were seen with the various Ara-C concentrations as above (Fig. 5A). In the graph below the blot, the Decrease in Mcl-1 Expression (±SE) is plotted against PARP Cleavage (±SE), where points representing the average of cells treated with 1–10 mM Ara-C are labeled and the unlabeled points represent cells not treated with Ara-C. …”

Sampling process. by Mahée Gilbert-Ouimet (3665080)

“…Participants were followed for a four-year period. We used an incremental cost method of difference-in-difference. …”

DataSheet1_Silver nanoparticle interactions with glycated and non-glycated human serum albumin mediate toxicity.PDF by Hee-Yon Park (14687089)

Image_3_Association of Dynamic Changes in Peripheral Blood Indexes With Response to PD-1 Inhibitor-Based Combination Therapy and Survival Among Patients With Advanced Non-Small Cel... by Yuzhong Chen (1556500)

“…The decrease or NLR at week 6 (OR = 3.081, 95%CI: 1.464-6.483) or 12 (OR = 3.304, 95%CI: 1.560-7.001) post-treatment, or CEA at week 12 post-treatment (OR = 2.469, 95%CI: 1.134-5.375), was associated with a higher objective response rate. …”

Image_2_Association of Dynamic Changes in Peripheral Blood Indexes With Response to PD-1 Inhibitor-Based Combination Therapy and Survival Among Patients With Advanced Non-Small Cel... by Yuzhong Chen (1556500)

“…The decrease or NLR at week 6 (OR = 3.081, 95%CI: 1.464-6.483) or 12 (OR = 3.304, 95%CI: 1.560-7.001) post-treatment, or CEA at week 12 post-treatment (OR = 2.469, 95%CI: 1.134-5.375), was associated with a higher objective response rate. …”

Table_1_Association of Dynamic Changes in Peripheral Blood Indexes With Response to PD-1 Inhibitor-Based Combination Therapy and Survival Among Patients With Advanced Non-Small Cel... by Yuzhong Chen (1556500)

“…The decrease or NLR at week 6 (OR = 3.081, 95%CI: 1.464-6.483) or 12 (OR = 3.304, 95%CI: 1.560-7.001) post-treatment, or CEA at week 12 post-treatment (OR = 2.469, 95%CI: 1.134-5.375), was associated with a higher objective response rate. …”

Table_1_Association of Dynamic Changes in Peripheral Blood Indexes With Response to PD-1 Inhibitor-Based Combination Therapy and Survival Among Patients With Advanced Non-Small Cel... by Yuzhong Chen (1556500)

“…The decrease or NLR at week 6 (OR = 3.081, 95%CI: 1.464-6.483) or 12 (OR = 3.304, 95%CI: 1.560-7.001) post-treatment, or CEA at week 12 post-treatment (OR = 2.469, 95%CI: 1.134-5.375), was associated with a higher objective response rate. …”

Table_2_Antimicrobial Use and Antimicrobial Resistance Indicators—Integration of Farm-Level Surveillance Data From Broiler Chickens and Turkeys in British Columbia, Canada.DOCX by Agnes Agunos (623419)

“…In turkeys, the mg/PCU_Tk decreased by 1%, whereas the nDDDvetCA/1,000 turkey-days and the nDDDvetCA/PCU increased by 1 and 5%, respectively. …”

Image_1_Association of Dynamic Changes in Peripheral Blood Indexes With Response to PD-1 Inhibitor-Based Combination Therapy and Survival Among Patients With Advanced Non-Small Cel... by Yuzhong Chen (1556500)

“…The decrease or NLR at week 6 (OR = 3.081, 95%CI: 1.464-6.483) or 12 (OR = 3.304, 95%CI: 1.560-7.001) post-treatment, or CEA at week 12 post-treatment (OR = 2.469, 95%CI: 1.134-5.375), was associated with a higher objective response rate. …”