Image 3_Beta-hydroxybutyrate (BHB) elicits concentration-dependent anti-inflammatory effects on microglial cells which are reversible by blocking its monocarboxylate (MCT) importer... by Chase Garcia (21803576)

“…We focused on 1.5 mM BHB, which reflects blood levels in mice and humans on a KD.…”

Impact of mutations in Toll-like receptor pathway genes on esophageal carcinogenesis by Daffolyn Rachael Fels Elliott (4039580)

“…Through interrogating whole genome sequencing data from 171 EAC patients, we showed that non-synonymous mutations collectively affect the TLR pathway in 25/171 (14.6%, PathScan p = 8.7x10^-5) tumors. …”

Prenatal Influences on Size, Velocity and Tempo of Infant Growth: Findings from Three Contemporary Cohorts by Costanza Pizzi (528116)

“…Some exposures only affected one growth parameter (e.g. maternal height (per cm): 0.4% increase in <i>size</i> (95% confidence interval (CI):0.3; 0.5)), others were either found to affect <i>size</i> and <i>velocity</i> (e.g. pre-pregnancy underweight vs normal weight: smaller <i>size</i> (−4.9%, 95% CI:−6.5; −3.3), greater <i>velocity</i> (5.9%, 95% CI:1.9;10.0)), or to additionally influence <i>tempo</i> (e.g. pre-pregnancy overweight/obesity vs normal weight: increased <i>size</i> (7.9%, 95% CI:4.9;10.8), delayed <i>tempo</i> (0.26 months, 95% CI:0.11;0.41), decreased <i>velocity</i> (−4.9%, 95% CI: −10.8;0.9)).…”

Data_Sheet_1_Chronic Δ9-tetrahydrocannabinol impact on plasticity, and differential activation requirement for CB1-dependent long-term depression in ventral tegmental area GABA neu... by Isaac Ostlund (14349531)

“…In young mice, VTA GABA cells exhibit a form of synaptic plasticity known as long-term depression (LTD) that is dependent on cannabinoid 1 (CB1) receptors preceded by metabotropic glutamate receptor 5 (mGluR5) signaling to induce endocannabinoid production. …”

Spatial learning in morris water maze. by Angela Kuhla (432300)

“…<p>(A–C) The escape latencies (in ms) of the training were displayed in five blocks (x-axis 1–5). One block consisted of four consecutive trials. …”

Image1_Neonatal outcomes in preterm infants with severe congenital heart disease: a national cohort analysis.jpeg by Safwat Aly (18346473)

“…Shunt lesions had the highest incidence of NEC (8.5%) compared to 5.3% in cyanotic CHD and 3.7% in left-sided lesions (p < 0.001). …”

Image1_Topiramate inhibits adjuvant-induced chronic orofacial inflammatory allodynia in the rat.pdf by Violetta Mohos (19431433)

“…To determine the optimal concentration for drug effect analysis, we tested the effects of two different CFA-concentrations (1 and 0.5 mg/mL) on mechanonociceptive thresholds. …”

Image1_Topiramate inhibits adjuvant-induced chronic orofacial inflammatory allodynia in the rat.pdf by Violetta Mohos (19431433)

“…To determine the optimal concentration for drug effect analysis, we tested the effects of two different CFA-concentrations (1 and 0.5 mg/mL) on mechanonociceptive thresholds. …”

Table1_Neonatal outcomes in preterm infants with severe congenital heart disease: a national cohort analysis.pdf by Safwat Aly (18346473)

“…Shunt lesions had the highest incidence of NEC (8.5%) compared to 5.3% in cyanotic CHD and 3.7% in left-sided lesions (p < 0.001). …”

Minocycline treatment inhibits activation of microglia. by Rosa M. Ferrer-Martín (623505)

“…Bars represent mean values ± SEM of 12 experimental explants with their respective controls for A, and 5 for B. …”

Cell morphology varies among genetically distinct subgroups. by Laura K. Jackson (9922803)

“…Side curvature and wavenumber values were normalized by cell centerline axis length. (<b>B</b>) Mean side curvature values normalized by centerline axis length (sc:al) is decreased in rod shaped cells (<0.7, as indicated by y-axis line) and (<b>C</b>) wavenumber normalized by centerline axis length (wn:al) is increased for cells that have increased wavenumber (>0.225, as indicated by y-axis line). …”

Data_Sheet_1_Effects of deforestation on dissolved organic carbon and nitrate in catchment stream water revealed by wavelet analysis.docx by Kerri-Leigh Robinson (14065467)

“…This study found that after deforestation, there was an immediate increase in in-stream DOC concentrations, followed by an increase in nitrate ~1 year later. Overall, the mean DOC concentration increased, and mean nitrate concentration decreased across the catchment post-deforestation. …”

Gain and loss of Miple expression affect lifespan in <i>Drosophila</i>. by Fredrik Hugosson (252549)

“…<p>(<b>A</b>) Loss of Miple proteins affect lifespan. Decreased mean lifespan is observed in <i>miple1^Δ194/Df(3L)BSC125</i> (open circles) and <i>miple2^Δ396/Df(3L)BSC125</i> (filled triangles) single mutant flies as well as <i>miple1,miple2^Δ104/Df(3L)BSC125</i> (open triangles) double mutants. …”

PDGFRA surface expression is down-regulated by MEK inhibitor U0126. by Dongfeng Chen (405191)

“…ΔCt was calculated by the mean Ct value of PDGFRA subtracted with the mean Ct value of GAPDH. …”

Measurement of lysosome proteolytic and acidic functions in response to PIKfyve inhibition and ROS. by Golam T. Saffi (11747438)

“…(D) RAW cells treated with vehicle or 20 nM apilimod for 40 min alone, or in combination with 1 μM rotenone for 60 min or 1 mM H₂O₂ for 40 min, and stained for LysoTracker Red as an indicator of lysosome acidification. Scale bar: 5 μm. (E) Quantification of mean lysotracker intensity per cell normalized to control cells. …”

Population statistics of latency tuning. by Oren Shriki (157992)

“…(A) Dependence of the mean DC component, <i>A</i>, on spike number (averaged over the population). …”

DISTRIBUTION OF TRACE ELEMENTS IN TISSUES OF Goniopsis cruentata (LATREILLE, 1803) CAUGHT FROM SOUTH OF BAHIA/ BRAZIL MANGROVES AND POTENTIAL OF RISK ASSESSMENT IN CONSUMPTION by Luanna M. Carneiro (5887538)

“…The concentration of Mn in the females in the three estuaries studied was 1.5 to 4.2 times higher than in the males. In general, detected mean metal concentrations in crab tissues were (in decreasing order) gills > hepatopancreas > muscles. …”

Invasive behavior of transformed cell lines. by Svetlana N. Rubtsova (775149)

“…The diagram shows the percentage of transformed cells that invaded the IAR-2 monolayer and spread on the glass substrate below the monolayer to the number of seeded cells at various time points (mean ± SEM, n = 40). Transfection of a dominant-negative mutant of E-cadherin dramatically decreased the invasion of the epithelial monolayer by transformed cells. …”

Genetic interaction between <i>mec-12(gm379)</i> and <i>unc-104</i>. by Jiun-Min Hsu (660083)

“…Quantifications are mean ± S.E.M. Scale bars  = 5 µm. *, <i>p</i><0.05; **, <i>p</i><0.001; ***, <i>p</i><0.0001, Mann-Whitney U test.…”

Real time monitoring of GFP-p65 using GFP knock-in MEF and live cell microscopy allows accurate quantification of single cell dynamics of endogenous p65. by Myong-Hee Sung (259774)

“…The ratio was obtained as the mean nuclear intensity divided by mean cellular intensity (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0007163#s4" target="_blank">Methods</a>). …”