Bimetallic η⁶,η¹ NCN-Pincer Ruthenium Palladium Complexes with η⁶-RuCp Coordination: Synthesis, X-ray Structures, and Catalytic Properties by Sylvestre Bonnet (1705354)

“…The synthesis, structure, and catalytic activity of a series of bimetallic η⁶,η¹-NCN-pincer ruthenium palladium complexes, [<b>3</b>]⁺−[<b>5</b>]⁺, have been studied, in which η⁶-coordination of [Ru(C₅R₅)]⁺ (R = H or Me) is realized either directly to the central arene ring of the NCN-pincer palladium complex ([<b>3</b>]⁺ and [<b>4</b>]⁺) or to the <i>para</i>-phenyl substituent ([<b>5</b>]⁺). …”

Image1_Mitral regurgitation increases systolic strains in remote zone and worsens left ventricular dyssynchrony in a swine model of ischemic cardiomyopathy.jpeg by Yuta Kikuchi (715512)

“…Group-wise comparison of LS and CS between BL and 2.5M demonstrated that LS and CS in the infarction zone and the border zone decreased at 2.5M in both groups. …”

An Upstream Open Reading Frame Modulates Ebola Virus Polymerase Translation and Virus Replication by Reed S. Shabman (278818)

“…To date, specific functions have not been assigned to these UTRs. With reporter assays, we demonstrated that the Zaire ebolavirus (EBOV) 5′-UTRs lack internal ribosomal entry site function. …”

Image2_Mitral regurgitation increases systolic strains in remote zone and worsens left ventricular dyssynchrony in a swine model of ischemic cardiomyopathy.jpeg by Yuta Kikuchi (715512)

“…Group-wise comparison of LS and CS between BL and 2.5M demonstrated that LS and CS in the infarction zone and the border zone decreased at 2.5M in both groups. …”

Supplementary Material for: Caffeine Prevents Hyperoxia-Induced Functional and Structural Lung Damage in Preterm Rabbits by Nagatomo T. (4158886)

“…Caffeine also improved histology by decreasing alveolar size [linear intercepts; N-P: 83.6 ± 1.7, H-P: 82.9 ± 1.6 and H-C: 67.3 ± 1.4 (p < 0.05)], increasing radial alveolar count (N-P: 6.6 ± 0.5, H-P: 5.7 ± 0.6 and H-C: 7.05 ± 0.5) and decreasing the acute inflammation score [N-P: 0.3 ± 0.1, H-P: 0.5 ± 0.1 and H-C: 0.4 ± 0.1 (p < 0.05)]. …”

DataSheet1_Loss of filamentous actin, tight junction protein expression, and paracellular barrier integrity in frataxin-deficient human brain microvascular endothelial cells—implic... by Frances M. Smith (17770776)

“…</p><p>Results: We investigated cytoskeletal architecture, identifying decreased filamentous actin and Occludin and Claudin-5 tight junction protein expression in shFXN hBMVECs. …”

Image_3_Prenatal Ethanol Exposure Misregulates Genes Involved in Iron Homeostasis Promoting a Maladaptation of Iron Dependent Hippocampal Synaptic Transmission and Plasticity.tif by Erwin De La Fuente-Ortega (7831502)

“…In agreement with these results, we found a 1.5–2 fold increase of TfR and DMT1 protein levels both in the hippocampus and the PFC. …”

Table_1_Prenatal Ethanol Exposure Misregulates Genes Involved in Iron Homeostasis Promoting a Maladaptation of Iron Dependent Hippocampal Synaptic Transmission and Plasticity.docx by Erwin De La Fuente-Ortega (7831502)

“…In agreement with these results, we found a 1.5–2 fold increase of TfR and DMT1 protein levels both in the hippocampus and the PFC. …”

Table_3_Prenatal Ethanol Exposure Misregulates Genes Involved in Iron Homeostasis Promoting a Maladaptation of Iron Dependent Hippocampal Synaptic Transmission and Plasticity.docx by Erwin De La Fuente-Ortega (7831502)

“…In agreement with these results, we found a 1.5–2 fold increase of TfR and DMT1 protein levels both in the hippocampus and the PFC. …”

Table_2_Prenatal Ethanol Exposure Misregulates Genes Involved in Iron Homeostasis Promoting a Maladaptation of Iron Dependent Hippocampal Synaptic Transmission and Plasticity.docx by Erwin De La Fuente-Ortega (7831502)

“…In agreement with these results, we found a 1.5–2 fold increase of TfR and DMT1 protein levels both in the hippocampus and the PFC. …”

Image_4_Prenatal Ethanol Exposure Misregulates Genes Involved in Iron Homeostasis Promoting a Maladaptation of Iron Dependent Hippocampal Synaptic Transmission and Plasticity.tif by Erwin De La Fuente-Ortega (7831502)

“…In agreement with these results, we found a 1.5–2 fold increase of TfR and DMT1 protein levels both in the hippocampus and the PFC. …”

Table_1_Absence of Thyroid Hormone Induced Delayed Dendritic Arborization in Mouse Primary Hippocampal Neurons Through Insufficient Expression of Brain-Derived Neurotrophic Factor.... by Hiroyuki Yajima (2108134)

“…However, the mechanisms of TH action in the developing hippocampus are still largely unknown. In this study, we generated 3,5,3’-tri-iodo-l-thyronine (T₃)-free neuronal supplement, based on the composition of neuronal supplement 21 (NS21), to examine the effect of TH in the developing hippocampus using primary cultured neurons. …”

DataSheet_1_Prenatal Ethanol Exposure Misregulates Genes Involved in Iron Homeostasis Promoting a Maladaptation of Iron Dependent Hippocampal Synaptic Transmission and Plasticity.p... by Erwin De La Fuente-Ortega (7831502)

“…In agreement with these results, we found a 1.5–2 fold increase of TfR and DMT1 protein levels both in the hippocampus and the PFC. …”

Image_2_Prenatal Ethanol Exposure Misregulates Genes Involved in Iron Homeostasis Promoting a Maladaptation of Iron Dependent Hippocampal Synaptic Transmission and Plasticity.tif by Erwin De La Fuente-Ortega (7831502)

“…In agreement with these results, we found a 1.5–2 fold increase of TfR and DMT1 protein levels both in the hippocampus and the PFC. …”

DataSheet_1_Absence of Thyroid Hormone Induced Delayed Dendritic Arborization in Mouse Primary Hippocampal Neurons Through Insufficient Expression of Brain-Derived Neurotrophic Fac... by Hiroyuki Yajima (2108134)

“…However, the mechanisms of TH action in the developing hippocampus are still largely unknown. In this study, we generated 3,5,3’-tri-iodo-l-thyronine (T₃)-free neuronal supplement, based on the composition of neuronal supplement 21 (NS21), to examine the effect of TH in the developing hippocampus using primary cultured neurons. …”

Image_1_Prenatal Ethanol Exposure Misregulates Genes Involved in Iron Homeostasis Promoting a Maladaptation of Iron Dependent Hippocampal Synaptic Transmission and Plasticity.tiff by Erwin De La Fuente-Ortega (7831502)

“…In agreement with these results, we found a 1.5–2 fold increase of TfR and DMT1 protein levels both in the hippocampus and the PFC. …”

Candidate receptors queried for a role in MPO-trafficking using shRNA knockdown and NH₄Cl in T47D-MPO cells. by Richard P. Laura (2149180)

“…The conditioned media and cell extracts were then assayed for: (i) hexosaminidase activity using a fluorogenic substrate; (ii) MPO content by ELISA to assess the treatments effects on the secretion; (iii) hexosaminidase activity and MPO concentration determined from the corresponding assays in i and ii were graphed as a ratio of that present in cell extracts divided by that present in the conditioned media (cells/media). Assay points are quadruplicate (i) and triplicate (II) measurements and plotted as mean ± SE. …”

Combination treatment reduces cell viability and induces apoptosis in TOM-1 cells and both drug combined do not antagonize each other. by Saskia Maletzke (13003764)

“…<b>(B)</b> Cell viability decreased to 73.49±10.2% after three days of dasatinib treatment while bortezomib treatment left only 17.78±13.7% of cells alive at this time point. …”

Bone phenotype of <i>Klotho^−/−</i> mice is rescued in <i>Klotho^−/−/VDR^Δ/Δ</i> compound mutants. by René Anour (333625)

“…All animals were fed the rescue diet. Each data point is the mean ± SEM of 6–7 animals per genotype. * denotes P<0.05 vs. …”

Depletion of Hth and Exd in the IPCs results in phenotypes associated with reduced systemic insulin signalling. by Mattias Winant (11058237)

“…(G) IPC-specific depletion of hth or exd resulted in decreased female fecundity. Every data point is the average (4–5 females per vial) cumulative number of eggs layed for 14 days (one-way ANOVA with post-hoc Dunnett’s test comparing to <i>mCherry</i>^<i>RNAi</i> controls * p <0.05,** p<0.01).…”