Image 5_Deciphering the oncogenic network: how C1QTNF1-AS1 modulates osteosarcoma through miR-34a-5p and glycolytic pathways.tif by Yu Zhang (12946)

“…</p>Discussion<p>Our research emphasizes the critical role of C1QTNF1-AS1 in the pathogenesis of osteosarcoma (OS). We discovered that the downregulation of C1QTNF1-AS1 indirectly upregulates the expression of LDHA and PDK3 by suppressing miR-34a-5p, which functions as a regulator of the Warburg effect. …”

Table 5_Deciphering the oncogenic network: how C1QTNF1-AS1 modulates osteosarcoma through miR-34a-5p and glycolytic pathways.doc by Yu Zhang (12946)

“…</p>Discussion<p>Our research emphasizes the critical role of C1QTNF1-AS1 in the pathogenesis of osteosarcoma (OS). We discovered that the downregulation of C1QTNF1-AS1 indirectly upregulates the expression of LDHA and PDK3 by suppressing miR-34a-5p, which functions as a regulator of the Warburg effect. …”

Gut richness and diversity decrease significantly by week 5 of chemoradiotherapy. by Molly B. El Alam (10231830)

Modifying pregnenolone to decrease its lipophilicity results in decreased cellular uptake. by Jeffrey M. McManus (7512926)

<i>Furin</i> mutant hearts show a decreased in the number of phospo-Smad positive cells at the AV junction. by Laurent Dupays (2940330)

Decreased transcription of <i>prs</i> results in decreased growth. by Javiera Norambuena (137228)

Significantly decreased adhesion to host cells by the Δ<i>tad123</i> mutant (A) and time-dependent recovery (B). by Tra-My Duong-Nu (7300970)

Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

“…We describe the discovery of a thioester-containing glucocorticoid receptor modulator (GRM) payload and the corresponding antibody–drug conjugate (ADC). …”

Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model by Christopher C. Marvin (1338228)

“…We describe the discovery of a thioester-containing glucocorticoid receptor modulator (GRM) payload and the corresponding antibody–drug conjugate (ADC). …”

HAstV-1 infection leads to a decrease in epithelial markers while increasing mesenchymal markers. by Virginia Hargest (12447014)

Chemokines, with the exception of CXCL1 and MCP-1, decrease acutely following 5 Gy IR. by Jordan A. Gunning (18143970)

Fig6B_modifiedSplitter_adjustTidalVolume_Patients_C_C_decrease: Variables for pair C-C, where the Tidal Volume of one patient was decreased by 30% whilst maintaining the other pati... by José A. Solís-Lemus (9272948)

Klf5 activates the transcription of the eIF5a gene through direct binding to its promoter. by Dong Ma (584680)

Subjects:

Klf5 and eIF5a suppress Ang II–induced expression of NOX1 in VSMCs. by Dong Ma (584680)

Subjects:

Pharmacological inhibition of EGFR decreases early fungal burden and reduces the inflammatory response. by Marc Swidergall (185453)

Data_Sheet_1_Immune and Neuroendocrine Trait and State Markers in Psychotic Illness: Decreased Kynurenines Marking Psychotic Exacerbations.docx by Livia De Picker (8319105)

“…Normalization of KA and 3-HK levels between admission and follow-up corresponded to a larger improvement of negative symptoms (r = 0.5, p < 0.030) A reverse association was found between relative improvement of SDST scores and decreasing KA levels (r = 0.5, p < 0.010).…”

LncRNA growth arrest specific transcript 5 inhibits the growth of pituitary neuroendocrine tumors via miR-27a-5p/cylindromatosis axis by Heyuan Wang (12425436)

“…Here, we found that lncRNA GAS5 and cylindromatosis (CYLD) expression was downregulated in invasive PitNET tissues and was negatively correlated with miR-27a-5p expression. …”

AUC statistics as calculated from simulated time series. Each statistical metric was calculated within sliding windows, throughout the pre-critical interval. We considered five-, fifteen-, and thirty-day sliding windows. Given that the temperature of the system increased to 12°C on day sixty, we also considered three pre-critical intervals: Days 1 to 60, Days 20 to 60, and Days 30 to 60. To evaluate trends in these metrics, we calculated Kendall’s rank correlation coefficient during the pre-critical interval, and compared control (constant temperature, non-epidemic) and warming (warming treatment, epidemic emergence) coefficients across simulations and experimental populations by calculating the area under the curve (AUC) statistic. Values less than 0.5 suggest that a decrease in the statistical metric indicates emergence, while values greater than 0.5 suggest that an increase in the statistical metric indicates emergence, with more extreme values indicating stronger tre by Madeline Jarvis-Cross (22394247)

“…Values less than 0.5 suggest that a decrease in the statistical metric indicates emergence, while values greater than 0.5 suggest that an increase in the statistical metric indicates emergence, with more extreme values indicating stronger tre</p>…”

Eliminations of dorsal projections in DOM and DOM-A downregulation were due to reduced number of sLNvs and decrease of PDF. by Zhenxing Liu (399809)

Data_Sheet_1_Increased selenium and decreased iron levels in relation to risk of coronary artery disease in patients with diabetes.PDF by Mengyun Tian (14712319)

“…</p>Results<p>Genetically predicted selenium level was causally associated with a higher risk of CAD in diabetic patients (odds ratio [OR]: 1.25; 95% confidence interval [CI]: 1.10–1.42; p = 5.01 × 10⁻⁴). …”