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521
TUDCA decreases ER stress in HOX neonatal rat lungs.
Published 2022“…<p>(<b>A</b>) The expression levels of ER stress markers (P-PERK 0.6±0.1-fold, p<0.001, n = 5; PERK 0.7±0.1-fold, p = 0.00364, n = 5; P-IRE1α 0.6±0.0-fold, p<0.001, n = 5; IRE1α 0.6±0.1-fold, p<0.001, n = 5; GRP78 0.8±0.1-fold, p<0.001, n = 5; cleaved ATF6 0.1±0.0-fold, p<0.001, n = 5; spliced XBP1 0.3±0.0-fold, p<0.001, n = 5; 2 males and 3 females) are all decreased while the N-glycosylated VEGFR2 is increased (3.5±0.2-fold, p<0.001, n = 5) in HOX neonatal lungs at P10 indicating TUDCA can attenuate hyperoxia-induced ER stress. …”
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Silencing <i>cullin-1/5</i> decreased mRNA and protein expression of NF-κB dependent cytokines.
Published 2021Subjects: -
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Decreased expression of adipogenesis-related genes by baicalein in early stage of adipogenesis.
Published 2016“…Cells were prepared as described in the legend of Fig 5B. The data are presented as the value relative to that of the undifferentiated cells and are shown as the means ± S.D. from three experiments. …”
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533
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Decrease in IL-4 measured by standard ELISA.
Published 2011“…Each ELISA value is an average of two measurements. The decrease in IL-4 in the keratoconus pool (7.6±5 pg/ml), compared to controls (14.2±8.6 pg/ml) was statistically significant (p≤0.05, Mann-Whitney test). …”
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540
PBA decreases ER stress induced apoptosis.
Published 2010“…All three ER stress inducing agents elicited a two-three fold increase in pycnotic nuclei. The fraction of cells with pycnotic nuclei decreased with PBA treatment—in the thapsigargin treated cells, the number of pycnotic nuclei was identical to the untreated cells by 1 mM PBA, and by 5 mM PBA the fraction of cells with pycnotic nuclei reached basal levels in all three treatment groups (B).…”