Multicenter Phase 2 Trial of Sirolimus for Tuberous Sclerosis: Kidney Angiomyolipomas and Other Tumors Regress and VEGF- D Levels Decrease by Sandra L. Dabora (206838)

“…Kidney angiomyolipomas regrew when sirolimus was discontinued but responses tended to persist if treatment was continued after week 52. We observed regression of brain tumors (SEGAs) in 7/11 cases (26% mean decrease in diameter), regression of liver angiomyolipomas in 4/5 cases (32.1% mean decrease in longest diameter), subjective improvement in facial angiofibromas in 57%, and stable lung function in women with TSC/LAM (n = 15). …”

Image1_Decreased mitochondrial respiration associates with frailty in community-dwelling older adults.jpg by Gianella Liabeuf (18512634)

“…The mean age of the participants was 80.2 ± 5.2 years, similar in both groups of men and women. …”

CaMKKβ is involved in ST2-104-regulated decrease in autophagy. by Yingshi Ji (9013004)

CaMKKβ contributes to the decrease in apoptosis conferred by ST2-104. by Yingshi Ji (9013004)

Rcan2-mediated decrease in intracellular K⁺ involves Kcnk5b. by Xiaowen Jiang (8291814)

Powdery Mildew Decreases the Radial Growth of Oak Trees with Cumulative and Delayed Effects over Years by Didier Bert (3171177)

“…Oak infection was monitored at individual tree level, at two sites in southwestern France, over a five-year period (2001–2005). …”

Effect of perfusion with VEGF121 on outflow facility. by Tomokazu Fujimoto (709192)

Overexpression of CCP5A and CCP5B induced flagellum length decrease and cell cycle defects. by Louise Basmaciyan (4576624)

Cardamonin decreased the expression of lipogenic proteins. by Peiguang Niu (17044532)

Knockdown of AR expression decreases the efficiency of KSHV infection in endothelial cells. by Xing Wang (154377)

“…(g, h) Knockdown of AR and EphA2 expression decreases nuclear LANA expression in SLK cells, as determined by an immunofluorescence assay and quantitative analysis by Image J software. …”

Decreasing ShcA expression enhances TGF-β-induced Smad signaling. by Baby Periyanayaki Muthusamy (838234)

“…The error bars show standard error of the mean, based on three independent experiments. Supplemental data are shown in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1002325#pbio.1002325.s006" target="_blank">S5 Fig</a> and <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1002325#pbio.1002325.s001" target="_blank">S1 Data</a>.…”

Percentage decrease in model output peak with the administration of exogenous estrogen/progesterone. by Brenda Lyn A. Gavina (15285185)

Image_5_Topoisomerase 2B Decrease Results in Diastolic Dysfunction via p53 and Akt: A Novel Pathway.TIF by Rohit Moudgil (540119)

Image_5_Topoisomerase 2B Decrease Results in Diastolic Dysfunction via p53 and Akt: A Novel Pathway.TIF by Rohit Moudgil (540119)

Apoptosis inhibitor prevented the decrease of IIL ESP-induced TJs expression and alleviated barrier disruption of Caco-2 monolayer. by Qi Qi Lu (17721401)

Reduction of Tks5 expression in tumor cells is associated with decreased angiogenesis. by Barbara Blouw (715467)

Effects of Remote Ischemic Preconditioning on Decreasing Troponin Release in Patients Not Taking Sulfonylureas After Cardiac Surgery – A Meta-Analysis by Xiaotong Wang (276499)

Effects of Remote Ischemic Preconditioning on Decreasing Troponin Release in Patients Not Taking Sulfonylureas After Cardiac Surgery – A Meta-Analysis by Xiaotong Wang (276499)

5-FU induces a decrease in the total cell number in cultures of smooth muscle cells. by Marcelo de Carvalho Filgueiras (408321)

“…Quantification of the number of nuclei per field revealed that 5-FU treatment induced a decrease in cell number in all the concentrations tested (<b>G</b>). …”

ML246 and voluntary exercise decrease cerebral amyloid plaques and ameliorate memory deficits in 5XFAD AD mice. by Altea Rocchi (3278457)