Conflicting selection pressures prevent the outgrowth of TIP-resistant HIV mutants in a host population. by Luke I. Rast (2735782)

“…For example, at <i>P</i> = 2.5, decreasing <i>η</i> results in major increases in transmission from TIP⁺ individuals (<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1004799#pcbi.1004799.g001" target="_blank">Fig 1B</a>) that overwhelm the modest decreases in transmission from TIP^- individuals, essentially removing the evolutionary conflict at the population-scale. …”

A new process for the recovery of ammonia from ammoniated high-salinity brine by Mohammad, Ameera F.

“…The initial ammonia concentration in a Solvay effluent of 13,700 mg/L N was decreased to 190 mg/L N. …”
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Is urotherapy alone as effective as a combination of urotherapy and biofeedback in children with dysfunctional voiding? by Adem Altunkol (5912324)

“…Subsequently, biofeedback sessions were added for all patients, and the changes in the results were recorded and statistically compared. Results: A total of forty - five patients were included, of which 34 were female and 11 were male and the average age of the patients was 8.4 ± 2.44 years (range: 5 - 15 years). …”

Capillary HILIC-MS: A New Tool for Sensitive Top-Down Proteomics by Andrea F.G. Gargano (5236496)

“…Overall, this allows the separation and detection of small protein quantities (down to 5 ng injected on column) as indicated by the analysis of a mixture of model proteins. …”

<i>NDE1</i> plays a critical role in the action of binaphthoquinones. by Ashkan Emadi (248270)

“…Spot assays were performed in duplicate in two separate experiments with representative plates shown. (<i>B</i>) Decreased generation of ROS in the <i>nde1</i>Δ<i>nde2</i>Δ mutant following exposure to 5 µM BiQ7. …”

Capillary HILIC-MS: A New Tool for Sensitive Top-Down Proteomics by Andrea F.G. Gargano (5236496)

“…Overall, this allows the separation and detection of small protein quantities (down to 5 ng injected on column) as indicated by the analysis of a mixture of model proteins. …”

A Chromosome-Level Reference Genome Assembly and Evolution of Dongxiang Wild Rice by chunxiu shen (8944760)

“…A total of 58.41 Gb clean data were de novo assembled into 231 contigs with the total length of 413.46 Mb and N50 length of 5.18 Mb. …”

Epidemiology of Orbital and Preseptal Cellulitis in the United States: A 13-Year Analysis by Shazia Dharssi (20563728)

“…Young adults (ages 21–44) comprise a majority of patients with either preseptal or orbital cellulitis (31.7%; 95% CI, 30.5–33.0%). …”

The levels of complex lipids are altered in the mitochondria of CPT1A^KD cells. by Cong-Hui Yao (2013793)

“…All lipids profiled that showed a fold difference ≥ 1.5, a <i>p</i>-value ≤ 0.01, and a signal intensity ≥ 10,000 are displayed. …”

B28Bn(6–14)-induced loss of mitochondrial transmembrane potential. A by Hao Yang (328526)

A potential novel inflammation biomarker for predicting the prognosis of decompensated liver cirrhosis by Yanan Xie (2609146)

“…</p> <p>In the development cohort, there were 16 (7.5%), 22 (10.3%) and 30 patients (14.0%) who died at 1, 3 and 6 months, respectively. …”

The representative trace of the LDF signal after the intravital injection of ADP to a mouse (a), parameters of the curve calculated by PAMA software, the LDU values are multiplied... by Tomasz Przygodzki (4277908)

“…<p>The following parameters characterizing the curve were calculated using PAMA software, as described in ‘<i>Materials and Methods</i>’ and are expressed in arbitrary Laser Doppler Flow units (LDU): <b>A</b>_<b>max</b><b>—</b>the maximum decrease in blood flow with respect to the baseline; <b>DA–</b>the maximal restoration of flow with respect to the baseline; <b>T</b>_<b>d</b><b>—</b>time from the injection of ADP to 10% of the maximum decrease in blood flow (A_max); <b>T</b>_<b>r</b><b>−</b>time from 10% to 90% of the maximum decrease in blood flow (A_max); <b>T</b>_<b>c</b><b>−</b>time from 90% of A_max to 90% of DA; <b>T</b>_<b>f</b><b>−</b>time from 90% of DA to 10% of DA; <b>V</b>_<b>0r</b><b>–</b>the maximal rate of the decrease in blood flow; <b>V</b>_<b>Avgr</b><b>−</b>the rate of decrease averaged through T_r; <b>V</b>_<b>0f</b><b>–</b>the maximal rate of the restoration of blood flow; <b>V</b>_<b>Avgf</b><b>−</b>the rate of restoration averaged through T_f; <b>AUC–</b>the area under the curve from 10% of A_max to 10% DA; <b>AUC</b>_<b>r</b><b>−</b>the area under the curve from 10% to 90% of A_max; <b>AUC</b>_<b>c</b><b>−</b>the area under the curve from 90% of A_max to 90% of DA; <b>AUC</b>_<b>f</b><b>−</b>the area over the curve from 90% to 10% of DA.…”

Deformative Transition of the Menschutkin Reaction and Helical Atropisomers in a Congested Polyheterocyclic System by Yung-Yu Chang (1724704)

“…Conformational flexibility in dipyridylethene <b>9</b> is clearly shown by its complexation with BH₃ to form helical atropisomers (<i>P,P</i>/<i>M,M</i>)-<b>10</b>. The p<i>K</i>_a values of the conjugate acids of <b>1A</b> and <b>9</b> in acetonitrile were determined to be 4.65 and 5.07, respectively, which are much smaller compared to that of pyridine <b>14a</b> (p<i>K</i>_a = 12.33), implying that the basicity, nucleophilicity, and amine alkylation rates of <b>1A</b> and <b>9</b> are markedly decreased by the severe steric hindrance of the flanking phenyl rings in the polyheterocycles.…”

Predictors of Visceral Leishmaniasis Relapse in HIV-Infected Patients: A Systematic Review by Gláucia F. Cota (218288)

“…Two studies found that baseline CD4+ T cell count above 100 cells/mL was associated with a decreased relapse rate. The observation of an increase in CD4+ T cells at patient follow-up was associated with protection from relapse in 5 of 7 studies. …”

Deformative Transition of the Menschutkin Reaction and Helical Atropisomers in a Congested Polyheterocyclic System by Yung-Yu Chang (1724704)

“…Conformational flexibility in dipyridylethene <b>9</b> is clearly shown by its complexation with BH₃ to form helical atropisomers (<i>P,P</i>/<i>M,M</i>)-<b>10</b>. The p<i>K</i>_a values of the conjugate acids of <b>1A</b> and <b>9</b> in acetonitrile were determined to be 4.65 and 5.07, respectively, which are much smaller compared to that of pyridine <b>14a</b> (p<i>K</i>_a = 12.33), implying that the basicity, nucleophilicity, and amine alkylation rates of <b>1A</b> and <b>9</b> are markedly decreased by the severe steric hindrance of the flanking phenyl rings in the polyheterocycles.…”

Deformative Transition of the Menschutkin Reaction and Helical Atropisomers in a Congested Polyheterocyclic System by Yung-Yu Chang (1724704)

“…Conformational flexibility in dipyridylethene <b>9</b> is clearly shown by its complexation with BH₃ to form helical atropisomers (<i>P,P</i>/<i>M,M</i>)-<b>10</b>. The p<i>K</i>_a values of the conjugate acids of <b>1A</b> and <b>9</b> in acetonitrile were determined to be 4.65 and 5.07, respectively, which are much smaller compared to that of pyridine <b>14a</b> (p<i>K</i>_a = 12.33), implying that the basicity, nucleophilicity, and amine alkylation rates of <b>1A</b> and <b>9</b> are markedly decreased by the severe steric hindrance of the flanking phenyl rings in the polyheterocycles.…”

Protein-protein docking for Parkin and a charged E2∼Ub complex. by Thomas R. Caulfield (655752)

“…The docking in the same position is shown and rotated 180° to reveal the other side. Residues of the Ubch5a-Ub complex are indicated by color (dark green and brown, respectively). …”

Cerebral Venous Sinus Thrombosis - Diagnostic Strategies and Prognostic Models: A Review by Penka A. Atanassova (7944506)

“…Patients with CVST commonly present with headache, although some develop a focal neurological deficit, decreased level of consciousness, seizures, or intracranial hypertension without focal neurological signs. …”

Factors associated with changing indications for adenotonsillectomy: A population-based longitudinal study by Jeng-Wen Chen (5310389)

“…Longitudinal data demonstrated an increasing trend in the pediatric AT rates from 1997 (4.3/100,000) to 2010 (5.7/100,000) (<i>p</i> = 0.029). In the adult subgroup, a decreasing prevalence of infectious indications (<i>p</i> = 0.014) coincided with an increasing neoplastic indications (<i>p</i> = 0.001). …”

Deformative Transition of the Menschutkin Reaction and Helical Atropisomers in a Congested Polyheterocyclic System by Yung-Yu Chang (1724704)

“…Conformational flexibility in dipyridylethene <b>9</b> is clearly shown by its complexation with BH₃ to form helical atropisomers (<i>P,P</i>/<i>M,M</i>)-<b>10</b>. The p<i>K</i>_a values of the conjugate acids of <b>1A</b> and <b>9</b> in acetonitrile were determined to be 4.65 and 5.07, respectively, which are much smaller compared to that of pyridine <b>14a</b> (p<i>K</i>_a = 12.33), implying that the basicity, nucleophilicity, and amine alkylation rates of <b>1A</b> and <b>9</b> are markedly decreased by the severe steric hindrance of the flanking phenyl rings in the polyheterocycles.…”