Image_4_Direct Current Stimulation Disrupts Endothelial Glycocalyx and Tight Junctions of the Blood-Brain Barrier in vitro.tif by Yifan Xia (11331264)

“…We found disrupted EG and ZO-1 when P to dextran-70k was increased and TEER was decreased by the DCS. To further investigate the cellular signaling mechanism of DCS on the BBB permeability, we pretreated the in vitro BBB with a nitric oxide synthase (NOS) inhibitor, L-NMMA. …”

Image_2_Direct Current Stimulation Disrupts Endothelial Glycocalyx and Tight Junctions of the Blood-Brain Barrier in vitro.tif by Yifan Xia (11331264)

“…We found disrupted EG and ZO-1 when P to dextran-70k was increased and TEER was decreased by the DCS. To further investigate the cellular signaling mechanism of DCS on the BBB permeability, we pretreated the in vitro BBB with a nitric oxide synthase (NOS) inhibitor, L-NMMA. …”

Image_3_Direct Current Stimulation Disrupts Endothelial Glycocalyx and Tight Junctions of the Blood-Brain Barrier in vitro.tif by Yifan Xia (11331264)

“…We found disrupted EG and ZO-1 when P to dextran-70k was increased and TEER was decreased by the DCS. To further investigate the cellular signaling mechanism of DCS on the BBB permeability, we pretreated the in vitro BBB with a nitric oxide synthase (NOS) inhibitor, L-NMMA. …”

Fig 5 - by Duyan Geng (12072181)

LGP2 overexpression decreases the transcript levels of the IFN signaling and proinflammatory cytokines during ZIKV infection. by Zhongyuan Tan (5779016)

Decreases in muscle size, muscle force, and TB mass in 3-mo Lmna^HSA-cko mice. by Lei Xiong (334812)

Data acquired from testing the effect of PAR1 inhibitors on Plasmodium falciparum-induced loss of endothelial cell barrier function by Janet Storm (8266991)

“…</div><div><br></div><div>The files are as follows:</div><div><div><b>-Combined analysis data for fig 2_TEER_includes normalisation.csv</b></div><div><b>-Combined analysis data for fig5_TEER_includes normalisation.csv</b></div><div><b>-Combined analysis data for fig6_TEER_includes normalisation.csv</b></div><div><b>-Data for fig2A+B+C_TEER_EA cells+inhibitors+thrombin_3.csv</b></div><div><b>-Data for fig2C_TEER_EA cells+inhibitors+thrombin_1.csv</b></div><div><b>-Data for fig2C_TEER_EA cells+inhibitors+thrombin_2.csv</b></div><div><b>-Data for fig3_flow cytometry HBMEC.csv</b></div><div><b>-Data for fig4A_TEER_aPC+thrombin_all time points shown.csv</b></div><div><b>-Data for fig4B_TEER_RBC+IE+lysate_all time points shown.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_#04-2+#91-2.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_#91-1.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_E5555-1+#04-1.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_E5555-2.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_Vorapaxar-1.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_Vorapaxar-2.csv</b></div><div><b>-Data for fig6_TEER_lysate_Vorapaxar+E5555+#04+#91-1.csv</b></div><div><b>-Data for fig6_TEER_lysate_Vorapaxar+E5555+#04+#91-2.csv</b></div><div><b>-Data for fig6_TEER_lysate_Vorapaxar+E5555+#04+#91-3.csv</b></div></div><div><br></div><div>The related publication investigated the hypothesis that the Thrombin-PAR1 coagulation/inflammation axis plays a significant role in barrier loss in cerebral malaria (CM), and that adjunct treatments targeting this might alleviate mortality or post-CM neurological sequelae in CM. …”

Discrimination performance deteriorated as the safe-to-conditioned ΔF decreased. by Chi Chen (67021)

The effects of NAC on the decreased number of myotube formations caused by arecoline. by Yi-Xuan Li (6633845)

Higher baseline PV rates decrease the need for interneuron specialization. by Joram Keijser (12475353)

Damage accumulation decreases elongation rates and displaces growth equilibrium. by Audrey Menegaz Proenca (845486)

“…<p>All panels depict MG1655 wild-type <i>E</i>. <i>coli</i>. (A) Exposure to phototoxic damage led to decreasing elongation rates in all treatment levels (length of exposure, every 2 min: 70 ms, 700 ms, 1 s, 1.5 s, 3 s). …”

PGRN decreased Dectin-2 expression on the surface of macrophages and neutrophils. by Jiayu Liu (3951515)

The monoterpene 1,8-cineole decreased parasitemia levels in vitro. by Edgleyson C. dos Santos (12536575)

DHA decreased cell viability in HepG3 cells. by Arlet Hernandez (12289155)

Over time, melanization decreases with aging, higher temperature, and infection. by Lindsay E. Martin (17377067)

Intratracheal hinokitiol injection decreases bacterial load in BALF and serum. by Toshihito Isono (8587668)

Absence of FumC leads to decreased susceptibility to bactericidal antibiotics. by Stephanie D. Himpsl (8501868)

Afatinib decreases MAPK and AKT activation after MET knockdown. by Karolin Ebert (7434713)

<i>B. bassiana</i> decreased longevity and impaired climbing. by Deepanshu N. D. Singh (20721878)

Loss of FOXP1 results in decreased number of bRGCs. by Seon Hye E. Park (16765033)