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581
STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS
Published 2024“…This study investigates the impact of five pathogenic CBS missense mutations [c.1006C>T (p.R336C), c.689T>A (p.L230Q), 215A>T (p.K72I), c.707C>A (p.T236N), and c.457G>A (p.G153R)] identified in homocystinuria patients and appeared to be resistant to pyridoxine treatment on the biochemical and biophysical properties of CBS protein. …”
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582
Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics
Published 2018“…In contrast, in the presence of Ca2+, there was a significant decrease in the stability of the five proteins following the order CaMWT> CaMN98I > CaMD132E > CaMQ136P > CaMD134H. …”
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583
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584
Investigating the utilization of healthcare services to manage respiratory tract infections (RTIs) among Qatari patients attended selected primary healthcare centers in Qatar
Published 2018“…We have found no difference in the month-to-month rates of RTI-related GP visits (per 1000 total visits) over the study period (non-significant decreasing trend). However, there was a significant decreasing trend in the monthly rates of antibiotics consumption and an increasing trend in the tests/investigations done but there was no clear increasing or decreasing trend in the monthly rates of other medications use. …”
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585
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586
Determining the role of missense mutations in the POU domain of HNF1A that reduce the DNA-binding affinity: A computational approach
Published 2017“…Missense mutations of the HNF1A were retrieved from public databases and subjected to a three-step computational mutational analysis to identify the underlying mechanism. …”
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587
Impact of Genetic Polymorphisms on Phenytoin Pharmacokinetics and Clinical Outcomes in the Middle East and North Africa Region
Published 2017“…Study quality was assessed using a National Institutes of Health assessment tool. …”
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588
The influence of aeration scheme and aeration rate on the permeate flux for wastewater treatment using membrane bioreactors: Experimental and artificial neural network modeling
Published 2021“…Furthermore, a continuous and pulsed aeration scheme (5 min on and 5 min off) was tested. …”
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589
Inhibition of alpha-synuclein seeded fibril formation and toxicity by herbal medicinal extracts.
Published 2020“…Therefore, examination of compounds that abolish the process of seeding is considered a key step towards therapy of several synucleinopathies. …”
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590
Flight Scheduling in the Airspace
Published 2016“…The mathematical model has been solved using CPLEX 12.6 and the scatter search has been coded using C language under Microsoft Visual Studio v12 environment. The tests were conducted under a Windows 7 machine with an Intel Core i7 and 8 GB of RAM. …”
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591
INVESTIGATION OF SPATIOTEMPORAL VARIABILITY AND CONTAMINATION OF PLASTIC MARINE DEBRIS IN QATAR’S COASTAL WATERS
Published 2015“…There has been a tremendous proliferation in plastic production in the last five decades due to its low cost and versatile applications. …”
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592
Microstructure and compressive behavior of Al-Y2O3 nanocomposites prepared by microwave-assisted mechanical alloying
Published 2019“…The Al–1.5 vol. % Y2O3 nanocomposite exhibited the best ultimate compressive strength and yielded a strength of 359 ± 7 and 111 ± 5 MPa, respectively. …”
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593
Functionalization of silica-coated magnetic nanoparticles as powerful demulsifier to recover oil from oil-in-water emulsion
Published 2021“…The Fe–Si-MNP exhibited excellent %Soil, reliable stability, and high magnetization values ranging between 46.1 and 80.2 emu/g. adding a 5 nm silica layer on the surface of the Fe–Si-MNP (i.e., Fe–Si-1) protected them from oxidation conditions, extended their service life, and achieved a %Soil of ∼96.3%. …”
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594
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596
Enhancing thermal and mechanical response of aluminum using nanolength scale TiC ceramic reinforcement
Published 2018“…the present work, nano-sized titanium carbide (0.5, 1.0 and 1.5 vol%) reinforced aluminum (Al) metal matrix composites were synthesized by powder metallurgy incorporating microwave sintering and hot extrusion. …”
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597
Novel, selective EPO receptor ligands lacking erythropoietic activity reduce infarct size in acute myocardial infarction in rats
Published 2016“…In study 4, AF43136 at 10 mg/kg decreased infarct size, similarly to the positive control CsA compared to the appropriate vehicle (39.4 ± 5.9% vs. 58.1 ± 5.4% and 45.9 ± 2.4% vs. 63.8 ± 4.1%, p < 0.05, respectively). …”
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598
Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide.
Published 2025“…Also, it enhanced glycemic control, as evidenced by significant reductions in hemoglobin A1C (HbA1c) with the 0.5 mg and 1.0 mg doses. From a baseline range of 8.1–8.7%, 0.5mg dose lowered HbA1c by 1.2–1.5%, while the 1.0 mg dose reduced it by 1.4–1.8%. …”
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599
Use and assessment of “e-plastics” as recycled aggregates in cement mortar
Published 2019“…The obtained results, for all RPs, (especially those of 7.5% and 10%) exhibited an increase in the CS of the specimens by 15.4% and 7.8%, respectively, with the MoE decreased in both cases by 18.1% and 23.8%, respectively. …”
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600
Enhancing compressive, tensile, thermal and damping response of pure Al using BN nanoparticles
Published 2018“…The addition of BN nanoparticulates enhanced the damping characteristics of pure Al with Al-1.5 vol.% BN nanocomposite exhibiting the maximum damping capacity and damping loss rate with a minimum change in elastic modulus. …”
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