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points decrease » point decrease (Expand Search), point increase (Expand Search)
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
3 points » _ points (Expand Search), _ point (Expand Search), 5 point (Expand Search)
points decrease » point decrease (Expand Search), point increase (Expand Search)
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
3 points » _ points (Expand Search), _ point (Expand Search), 5 point (Expand Search)
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OCA alone markedly decreases and combined with Gemcitabine or Cisplatin abrogates growth of iCCA xenografts.
Published 2019“…After 4 weeks, when the tumor size was approximately 100 mm<sup>3</sup> (T<sub>0</sub>) mice were treated with OCA (0.03% w/w, 30 mg/kg) alone or combined with Cisplatin (2.4 mg/Kg in 100 μl) or Gemcitabine (1.05 mg/Kg in 100 μl) for 5 additional weeks. a) Results are expressed as percent increase in tumor volume at different time points. …”
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Possible Points of Canonical Wnt Inhibition.
Published 2015“…Non canonical signalling is inhibitory to canonical signalling (2) Decreased Fzd receptor expression, reducing response to canonical ligands secreted by other cells (3) Increased sFRP expression (4) Increased expression of other morphogens such as Notch, able to directly inhibit βCatenin. …”
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Data_Sheet_5_Chronic Neurobehavioral Impairments and Decreased Hippocampal Expression of Genes Important for Brain Glucose Utilization in a Mouse Model of Mild TBI.xlsx
Published 2020“…There were no significant differences in NSS between injury and sham groups at any of the three time points. Thus, mTBI in male mice led to persistent decreased hippocampal expression of mRNAs that encode critical glucose utilization related enzymes in association with long-term impairments in selected neurobehavioral outcomes.…”
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Transepithelial electrical resistance (TEER) (N = 6).
Published 2024“…<p><b>(A)</b> During the cultivation of SMC and ALI we observed significantly differences on day 18 (SMC: 9.61 kΩ*cm<sup>2</sup>; ALI: 7.73 kΩ*cm<sup>2</sup>; p<0.05) and day 25 (SMC: 8.19 kΩ*cm<sup>2</sup>; ALI: 6.44 kΩ*cm<sup>2</sup>; p<0.05) ALI cultures showed significantly decreased values compared to SMC. …”
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BC−/EC+ exhibited increased end-systolic and end-diastolic volume and decreased left ventricular function 3 weeks post MI.
Published 2015“…<p>BC−/EC+ exhibited an increase in end-systolic (<b>A</b>) and end-diastolic volume (<b>B</b>), a significantly more pronounced decrease in stroke volume (<b>C</b>) (BC+/EC+ n = 8 and BC−/EC+ n = 5; two-way ANOVA and Bonferroni’s post hoc test or student’s t-test; * p<0.05, ** p≤ 0.01 BC+/EC+ vs. …”
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Validation of primary screen hits reveals compounds that recapitulate increased spheroid size (swell) or decreased MUC5AC in the lumen.
Published 2023“…Compounds that appeared to cause toxicity were identified by observing a significant decrease in spheroid counts in the swell readout or a significant decrease in the total nuclear intensity of the MUC5AC ratio readout. …”
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Inhibition of GLS1 decreases the proportion of CCR6 and CXCR3 expressing CD4<sup>+</sup> T cells.
Published 2016“…BPTES and 968 significantly decrease the proportion of CCR6 expressing cells under normoxia both at day 3 and 5, whereas 968 but not BPTES decrease the proportion of CCR6 expressing cells under hypoxia both at day 3 and 5. …”
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