Immunofluorescence analysis using dual staining for E-cadherin (E-cad) and afadin and F-actin in RPTECs infected with Oki53 and Oki65 at 24 h post-infection. by Tetsuya Kakita (4922584)

Proteosomal and pan-caspase inhibitors differentially prevent the disruption of the epithelial cell barrier by the clinical <i>Leptospira</i> isolates. by Tetsuya Kakita (4922584)

Expression of tight junction proteins. by Maj Schneider Thomsen (10297019)

“…<p>(A) Relative gene expression of claudin-1,-3,-5 (<i>Cld1</i>, <i>Cld3</i>, and <i>Cld5</i>), occludin (<i>Ocln</i>), and zonula occludens 1 and 2 (<i>Zo1</i>, <i>Zo2</i>) in mouse, rat, and porcine brain capillary endothelial cells (mBECs, rBECs, pBECs) cultured as mono-culture (black triangle) and as co-culture with primary astrocytes (blue circle). …”

Inhibition of the mitochondrial fission decreases mtROS production. by Dong Ma (584680)

Subjects:

Positional cloning of <i>qNN1</i> on chromosome 16. by Xinxin Li (281237)

eIF5a is up-regulated in unruptured AAAs and decreased in ruptured AAAs. by Dong Ma (584680)

Subjects:

Image_1_Direct Current Stimulation Disrupts Endothelial Glycocalyx and Tight Junctions of the Blood-Brain Barrier in vitro.tif by Yifan Xia (11331264)

“…We found disrupted EG and ZO-1 when P to dextran-70k was increased and TEER was decreased by the DCS. To further investigate the cellular signaling mechanism of DCS on the BBB permeability, we pretreated the in vitro BBB with a nitric oxide synthase (NOS) inhibitor, L-NMMA. …”

Image_4_Direct Current Stimulation Disrupts Endothelial Glycocalyx and Tight Junctions of the Blood-Brain Barrier in vitro.tif by Yifan Xia (11331264)

“…We found disrupted EG and ZO-1 when P to dextran-70k was increased and TEER was decreased by the DCS. To further investigate the cellular signaling mechanism of DCS on the BBB permeability, we pretreated the in vitro BBB with a nitric oxide synthase (NOS) inhibitor, L-NMMA. …”

Image_2_Direct Current Stimulation Disrupts Endothelial Glycocalyx and Tight Junctions of the Blood-Brain Barrier in vitro.tif by Yifan Xia (11331264)

“…We found disrupted EG and ZO-1 when P to dextran-70k was increased and TEER was decreased by the DCS. To further investigate the cellular signaling mechanism of DCS on the BBB permeability, we pretreated the in vitro BBB with a nitric oxide synthase (NOS) inhibitor, L-NMMA. …”

Image_3_Direct Current Stimulation Disrupts Endothelial Glycocalyx and Tight Junctions of the Blood-Brain Barrier in vitro.tif by Yifan Xia (11331264)

“…We found disrupted EG and ZO-1 when P to dextran-70k was increased and TEER was decreased by the DCS. To further investigate the cellular signaling mechanism of DCS on the BBB permeability, we pretreated the in vitro BBB with a nitric oxide synthase (NOS) inhibitor, L-NMMA. …”

PGAM5 knockdown prevented rTsSPc from disrupting Caco-2 monolayer integrity. by Qi Qi Lu (17721401)

Data acquired from testing the effect of PAR1 inhibitors on Plasmodium falciparum-induced loss of endothelial cell barrier function by Janet Storm (8266991)

“…</div><div><br></div><div>The files are as follows:</div><div><div><b>-Combined analysis data for fig 2_TEER_includes normalisation.csv</b></div><div><b>-Combined analysis data for fig5_TEER_includes normalisation.csv</b></div><div><b>-Combined analysis data for fig6_TEER_includes normalisation.csv</b></div><div><b>-Data for fig2A+B+C_TEER_EA cells+inhibitors+thrombin_3.csv</b></div><div><b>-Data for fig2C_TEER_EA cells+inhibitors+thrombin_1.csv</b></div><div><b>-Data for fig2C_TEER_EA cells+inhibitors+thrombin_2.csv</b></div><div><b>-Data for fig3_flow cytometry HBMEC.csv</b></div><div><b>-Data for fig4A_TEER_aPC+thrombin_all time points shown.csv</b></div><div><b>-Data for fig4B_TEER_RBC+IE+lysate_all time points shown.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_#04-2+#91-2.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_#91-1.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_E5555-1+#04-1.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_E5555-2.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_Vorapaxar-1.csv</b></div><div><b>-Data for fig5+6_TEER_lysate+thrombin_Vorapaxar-2.csv</b></div><div><b>-Data for fig6_TEER_lysate_Vorapaxar+E5555+#04+#91-1.csv</b></div><div><b>-Data for fig6_TEER_lysate_Vorapaxar+E5555+#04+#91-2.csv</b></div><div><b>-Data for fig6_TEER_lysate_Vorapaxar+E5555+#04+#91-3.csv</b></div></div><div><br></div><div>The related publication investigated the hypothesis that the Thrombin-PAR1 coagulation/inflammation axis plays a significant role in barrier loss in cerebral malaria (CM), and that adjunct treatments targeting this might alleviate mortality or post-CM neurological sequelae in CM. …”

Inhibition of PGAM5 and apoptosis alleviated the rTsSPc-damaged Caco-2 monolayer barrier integrity. by Qi Qi Lu (17721401)

Shoot-to-root translocation of GmNN1/FT2a regulates soybean nodulation. by Xinxin Li (281237)

Effects of SNPs on the Protein Stability, Increasing or Decreasing. by Mirza Jawad Ul Hasnain (8351388)

Decreased hypotaurine levels within cells lacking the ADO gene in U251 cells. by Hong Tian (169626)

Decreased Aβ42 halo overlaps with the decreased incidence of DNs in FO treated mice. by Milena Jović (6707702)

“…(E-H) In the FO-treated 5xFAD animals the decreased surface of the Aβ halo overlaps with the decreased incidence of swollen, dystrophic neurites.…”

The GmNN1/FT2a-GmNFYA-C-GmENOD40 module regulates soybean nodulation. by Xinxin Li (281237)

Downregulation of DOM decreases the abundance of PER and TIM. by Zhenxing Liu (399809)

“…Downregulation of DOM decreased PER levels at CT1-5 and CT17-21. (Scale bar: 50 um.) …”

Predictions of random forests (RF), gradient boosting machines (GBM), and neural networks (NN) trained on 12 covariates chosen using subjective feature selection. by Dennis Ochola (11626912)