DataSheet_1_PvML1 suppresses bacterial infection by recognizing LPS and regulating AMP expression in shrimp.docx by Yue Wang (65477)

“…We found that PvML1 shared a similar 3D structure with human MD2 that could specifically recognize lipopolysaccharides (LPS) participating in LPS-mediated TLR4 signaling. …”

Low turnover rates of thaumarchaeal intact polar tetraether lipids in sediments from the Iceland Shelf by Sabine Lengger (495518)

Free Fatty Acid Palmitate Impairs the Vitality and Function of Cultured Human Bladder Smooth Muscle Cells by Andreas Oberbach (107803)

“…We found: (i) palmitate decreased cell proliferation, increased mitochondrial enzyme activity and antioxidant capacity; (ii) direct inhibition of cytokine receptor by AG490 even more strongly suppressed cell proliferation in palmitate-stimulated cells, while counteracting palmitate-induced increase of antioxidant capacity; (iii) in contrast knockdown of the STAT3 inhibitor SOCS3 increased cell proliferation and antioxidant capacity; (iv) further downstream JAK/STAT3 signaling cascade the inhibition of PI3K or JNK enhanced palmitate induced suppression of cell proliferation; (v) increase of mitochondrial enzyme activity by palmitate was enhanced by inhibition of PI3K but counteracted by inhibition of MEK1.…”

Results of Association of Multi-SNP Genotypic Risk Score with Diabetes and Related Traits. by Zari Dastani (144367)

Image1_Transformation of Stilbene Glucosides From Reynoutria multiflora During Processing.JPEG by Junqi Bai (9899591)

“…However, the content of trans-2, 3, 5, 4′-tetrahydroxystilbene-2-O-β-D-glucopyranoside (trans-THSG), which is considered to be the main medicinal ingredient, decreases in this process. …”

Table1_Transformation of Stilbene Glucosides From Reynoutria multiflora During Processing.docx by Junqi Bai (9899591)

“…However, the content of trans-2, 3, 5, 4′-tetrahydroxystilbene-2-O-β-D-glucopyranoside (trans-THSG), which is considered to be the main medicinal ingredient, decreases in this process. …”

Long noncoding RNA (lncRNA) metallothionein 1 J, pseudogene (MT1JP) is downregulated in triple-negative breast cancer and upregulates microRNA-138 (miR-138) to downregulate hypoxia... by Gangyue Wang (12876316)

Data_Sheet_1_Long-Term Stress Disrupts the Structural and Functional Integrity of GABAergic Neuronal Networks in the Medial Prefrontal Cortex of Rats.docx by Boldizsár Czéh (5428088)

Data_Sheet_1_Contraction Phase and Force Differentially Change Motor Evoked Potential Recruitment Slope and Interhemispheric Inhibition in Young Versus Old.docx by Elsa Ermer (9463283)

“…It is unknown how increasing and decreasing contraction affect the opposite limb. Since dynamic muscle contraction is more ecologically relevant to daily activities, we studied MEP recruitment using a novel method and short interval interhemispheric inhibition (IHI) from active to resting hemisphere at 4 phases of contralateral ECR contraction: Rest, Ramp Up [increasing at 25% of maximum voluntary contraction (MVC)], Execution (tonic at 50% MVC), and Ramp Down (relaxation at 25% MVC) in 42 healthy adults. …”

Supplementary file 1_Single-cell and bulk transcriptomic analyses reveal PANoptosis-associated immune dysregulation of fibroblasts in periodontitis.zip by Erli Wu (17785482)

“…</p>Results<p>scRNA-seq analysis revealed a decreased proportion of HGFs alongside enrichment of multiple PANoptosis-related pathways in PD samples. …”

Localization of the KIFC1-like protein and microtubules in late spermatid in <i>O. tankahkeei</i>. by Wei Wang (17594)

“…I and J are higher magnifications of an area of “a” and “b” labled in G, respectively. Scale bar is 5 µm in (A–D), 1 µm in (E-G), 0.5 µm in (H) and 0.25 µm in (I and J). …”

MEG Network Differences between Low- and High-Grade Glioma Related to Epilepsy and Cognition by Edwin van Dellen (119663)

Prospects Of Amino Acids And Ionic Liquids As Natural Gas Hydrate Inhibitors For Offshore Flow Assurance by Qureshi, M. Fahed Aziz

“…The results show that the selected amino acids and ionic liquids exhibit dual functional behaviour by providing the temperature shift of around 1.5-2.3 oC and delaying the hydrate formation time from 0.5-1.5 hr. …”
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The acid-sensitive phenotype of the <i>0846</i>::<i>Tn</i> mutant strain can be bypassed by activating the stringent response. by Catrin M. Beetham (17797675)

“…<p>(A) Bacterial growth on TSA pH 4.5 plates. Overnight cultures of LAC* (WT), the <i>0846</i>::<i>Tn</i> mutant or the suppressor strains <i>0846</i>::<i>Tn-S1</i>, <i>0846</i>::<i>Tn-S2</i>, <i>0846</i>::<i>Tn-S3</i>, <i>0846</i>::<i>Tn-S4</i>, <i>0846</i>::<i>Tn-S5</i>, <i>0846</i>::<i>Tn-S6</i>, <i>0846</i>::<i>Tn-S7</i>, <i>0846</i>::<i>Tn-S8</i> were serially diluted and aliquots spotted on TSA pH 4.5 plates. …”

TRα2 shows dominant negative activity on positively and negatively regulated T₃ target genes <i>in vivo</i>. by Hajer Guissouma (586934)

“…</b><i>Trh-luc</i> transcription was measured in hypothyroid (PTU) 2 days old mice as described above (100 ng expression vector and 1 µg reporter gene, <i>Trh-luc</i> per pup). Transcription from a <i>Trh-luc</i> construct is significantly decreased both in absence (PTU) and presence of T₃ (PTU+T3) when TRα1 is overexpressed (as compared with Ct). …”

Log₂ Fold Change Heat Map. by Anna Slawinska (3220077)

“…Log₂ fold change calculate based on delta Ct value compared to the control samples and green implies increased expression while red implies decreased expression. Genes on the right are clustered using a hierarchical clustering method and 8 clusters were found. …”

Ribosome biogenesis is disrupted in <i>polr1c</i> and <i>polr1d</i> mutant embryos. by Kristin E. Noack Watt (223863)

“…(A) <i>polr1c</i>^-/- mutants exhibit reduced levels of 5’ETS (39%), ITS2 (23%) and 18S rRNA (58%) compared to controls. …”

Adaptation affects the gain and slope of neural power spectral densities. by Brian Nils Lundstrom (14659973)

“…<i>5</i>). (b) Relative steady-steady output for synaptic depression initially increases and then decreases as <i>x</i>_<i>0</i> increases (modeled via Eq (<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1010527#pcbi.1010527.e018" target="_blank">8</a>) with <i>n = 3</i>, <i>F = 0</i>.…”

MLR-Tregs non-specifically regulate cytotoxic activity in micro-CML generated by purified CD8⁺ plus autologous non-T “APC” responders. by Yuming Yu (212650)

“…<p>Micro-CML inhibition assays were performed with purified CD8⁺ responders as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0022450#pone-0022450-g005" target="_blank">Fig. 5</a>, but in presence of non-T “APCs” autologous to the responders, and the data are shown as: <b>(A) Percent specific lysis:</b> against the specific stimulator used both in MLR-Treg generation and the micro-CML readout. …”

Refractory Severe Thrombocytopenia during Pregnancy: How to Manage by Joana Gomes de Amorim (6303395)