MIB/MS kinome profiling reveals brigatinib target specificity in multiple <i>NF2</i>-deficient cell models. by Long-Sheng Chang (41691)

“…<p>(A-D) MIB/MS kinome profiling was performed following treatment of Syn1 and Syn5 cells with vehicle (DMSO), brigatinib (1μM) or the combination of MK-2206 (0.5μM) and brigatinib (1μM) for 24h in biological triplicate. …”

FGF inhibitor and six additional compounds that impair nerve regeneration after fin removal also impair regeneration after laser nerve transection. by Juliane Bremer (161529)

“…However, following laser nerve transection in both DMSO and 10-HCT treated larvae, the number of neurons decreased on average by 3 neurons, suggesting that a subset of neurons with transected axons died.…”

Bayesian estimate of the effective reproduction number <i>R_e</i> over time (from simulated data). by Remco Bouckaert (550308)

“…<p>Towards the end of the 3.5 years of the underlying epidemic process, <i>R_e</i> decreases below 1, which indicates a declining epidemic.…”

Table_1_BCR-ABL1 Doubling-Times and Halving-Times May Predict CML Response to Tyrosine Kinase Inhibitors.pdf by Maria Stella Pennisi (6371525)

“…We wanted to determine whether measuring BCR-ABL1 mRNA doubling-times (DTs) could distinguish inconsequential rises in the oncogene's expression from resistance to tyrosine kinase inhibitors (TKIs). …”

Excess osteopontin and TGFβ activation inhibits <i>Anxa1</i> and <i>Anxa6</i> gene expression. by Mattia Quattrocelli (2084083)

Data_Sheet_1_BCR-ABL1 Doubling-Times and Halving-Times May Predict CML Response to Tyrosine Kinase Inhibitors.PDF by Maria Stella Pennisi (6371525)

“…We wanted to determine whether measuring BCR-ABL1 mRNA doubling-times (DTs) could distinguish inconsequential rises in the oncogene's expression from resistance to tyrosine kinase inhibitors (TKIs). …”

Mice expressing the C/EBPβ-Ala217 transgene are refractory to the induction of lung injury. by Martina Buck (82941)

“…It was decreased in the lungs of C/EBPβ ^wt mice treated with Bleomycin, but not in the lungs of C/EBPβ-Ala217 mice treated with Bleomycin or in the lungs of C/EBPβ ^wt treated with Bleomycin and the C/EBPβ peptide as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0025497#s4" target="_blank">Methods</a>. …”

CT Perfusion with Acetazolamide Challenge in C6 Gliomas and Angiogenesis by Na Lu (325317)

“…Cerebral blood volume _{pre-challenge} was increased in group C (50.8±1.7ml/100g), as compared to group B (45.7±1.9 ml/100g) and group A (38.2±0.8 ml/100g). Cerebral blood volume percentage changes were decreased in group C (23.5±4.6%) as compared to controls (113.5±30.4%). …”

The rate of transcription is important for the <i>pbuE</i> riboswitch activity. by Jean-François Lemay (232703)

“…The complete gel is shown in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1001278#pgen.1001278.s005" target="_blank">Figure S5</a>. …”

Inexact GMRES: Laplace equation by Tingyu Wang (2299786)

“…</div><div><br></div><div>Fig. 5: (LaplaceConvergence.pdf)</div><div>Convergence of 1st-kind (solid line) and 2nd-kind (dotted line) solvers for the Laplace equation on a sphere, using a GMRES with FMM-accelerated matrix-vecctor products.…”

Data Sheet 1_Soil fungal community and co-occurrence network patterns at different successional stages of black locust coppice stands.docx by Huimei Tian (499744)

“…Shifts in fungal community composition were observed from seedling to coppice stands: Ascomycota dominance decreased (72.9 to 57.9%), while Basidiomycota increased (6.5 to 11.6%). …”

Mobile Epifauna Associated To Artificial Substrates In Offshore Qatari Waters by Abdulaziz Aziz, Naeem

“…Multivariate analysis for abundance and biomass showed that both Site and Depth, as well as their interaction, had significant effects on the mobile macrofaunal community. A general trend of total abundance and average number of taxa decreasing with depth was observed, although with some notable exceptions. …”
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[Continuous intravenous anesthesia with racemic ketamine or dextroketamine and detomidine in female dogs] by F.V. Henrique (10385210)

Image_2_P2Y6 and P2X7 Receptor Antagonism Exerts Neuroprotective/ Neuroregenerative Effects in an Animal Model of Parkinson’s Disease.TIF by Ágatha Oliveira-Giacomelli (7833929)

“…<p>Parkinson’s disease (PD) is a neurodegenerative disorder characterized by decreased dopamine bioavailability in the substantia nigra and the striatum. …”

Representative immunohistochemical images of tissue cross-sections obtained from rabbit corneas harvested 72-hours post-surgery. by Waleed Abdel-Naby (4603897)

“…<p>(A, left panels) The presence of staining for the cell proliferation marker Ki-67 increased in denuded PBS treated (Control) animals vs. untreated native corneas, in which Ki-67 staining was further increased with both 0.5% and 2.0% SDP treatment. …”

Image_3_P2Y6 and P2X7 Receptor Antagonism Exerts Neuroprotective/ Neuroregenerative Effects in an Animal Model of Parkinson’s Disease.TIF by Ágatha Oliveira-Giacomelli (7833929)

“…<p>Parkinson’s disease (PD) is a neurodegenerative disorder characterized by decreased dopamine bioavailability in the substantia nigra and the striatum. …”

Sporicidal evaluation of different substances against <i>Nosema ceranae</i> for surface disinfection by Cristina Rodríguez-García (10164001)

“…<p><i>Nosema ceranae</i> is the microsporidium causing a disease highly prevalent in honey bees. Since few treatments are available to control this disease, cleaning and disinfection of beekeeping equipment could be a useful tool for decreasing the number of viable spores and therefore the risk of infection. …”

Image_4_P2Y6 and P2X7 Receptor Antagonism Exerts Neuroprotective/ Neuroregenerative Effects in an Animal Model of Parkinson’s Disease.TIF by Ágatha Oliveira-Giacomelli (7833929)

“…<p>Parkinson’s disease (PD) is a neurodegenerative disorder characterized by decreased dopamine bioavailability in the substantia nigra and the striatum. …”

Data_Sheet_1_Screening of Key Drought Tolerance Indices for Cotton at the Flowering and Boll Setting Stage Using the Dimension Reduction Method.xlsx by FengLei Sun (11102019)

“…Therefore, the indicator dimension decreased from 19 to 5. A comparison of the 19 indicators with the 5 identified indicators through PCA and a combined regression analysis found that the results of the final cluster of drought tolerance on 104 cotton varieties were basically consistent. …”

Long-term pharmacological inhibition of mTOR signaling impairs retinal growth. by Fangfang Lu (664493)

“…<p>(A) Quantification of retinal size in larvae treated with DMSO, rapamycin, or INK128 from 4dpf-4dpi (long-term) showed significant decreases in inhibitor-treated larvae from unabated and ablated groups when compared to the corresponding DMSO-treated controls. …”