Down-regulation of NNMT expression inactivated Akt and ERK1/2. by Jun Zhang (48506)

“…Values in (C, D) are expressed as means ± SD of six independent experiments. The phosphorylation of Akt and ERK 1/2 was decreased significantly in both cell lines infected with NNMT shRNA 1# and shRNA 2# compared to negative control (*<i>P</i><0.05; **<i>P</i><0.01). …”

Knockdown of CrzR in fat body/salivary glands results affects body mass from Systemic corazonin signalling modulates stress responses and metabolism in <i>Drosophila</i> by Olga I. Kubrak (659970)

Cytoskeleton and matrix remodeling during acute thymic atrophy. by Matthew J. Billard (227285)

“…Arrows may represent multiple steps. Plasma membrane is shown in gray. A detailed version of the original Metacore pathway is found as <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0017940#pone.0017940.s002" target="_blank">Figure S2</a>. …”

Figure 3 by M. Ángeles Serrano (269739)

“…In Experiment 2 (open symbol lines), the order of edge deletion at the interfaces is random and also applied to the original networks under analysis. …”

Age-related changes in ADAR2 activity in the AHs and motor neurons. by Takuto Hideyama (141081)

“…The columns and bars represent the means ± SEMs. The data were analyzed using a Mann-Whitney U-test.…”

FLEXI interactions with RNA-binding proteins. by Jun Yao (9646)

“…RNA-binding sites: I, within introns corresponding to FLEXIs; SS-I and SS-E, bimodally enriched across the 5’- and 3’ splice sites in unspliced pre-mRNAs with the midpoints in the intron or flanking exon (SS-I and SS-E, respectively; Figs <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.g004" target="_blank">4A</a> and <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s011" target="_blank">S11</a>). mRNA levels, RBPs whose knockdown resulted in significant difference in mRNA levels (increased or decreased, DESeq2 |LFC|≥1, adjusted p≤0.05) from host gene of FLEXIs with a binding site for that RBP compared to those genes whose transcripts lacked a binding site for the same RBPs based on ENCODE RBP-knockdown datasets (p≤0.05 calculated by Fisher’s exact test; <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011416#pgen.1011416.s013" target="_blank">S13 Fig</a>). …”

Table plot of associations between cytokine levels and epidemiologic factors. by Song Yao (202481)

Norbornyl Cations of Group 14 Elements by Thomas Müller (3554)

“…In contrast, the intramolecular stabilization energy <i>E</i>_A of the norbornyl cations <b>4a</b>−<b>d</b> decreases, suggesting reduced interaction between the CC double bond and the electron-deficient element center in the plumbacation compared to the silacations. …”

Changes in corticosteroid gene expression in adrenal glands of Nf1Prx1 mice. by Karolina Kobus (512086)

“…T-test with Welch’s correction: 1 asterisks: p<0.1; 2 asterisks: p<0.01; 3 asterisks: p<0.001. (B) A diagram of the corticosterone synthesis pathway depicting synthesis steps and major genes involved in the catalysis. …”

<i>P2RX7</i> ablation in <i>mdx</i> mice reduces macrophage infiltration. by Anthony Sinadinos (694160)

“…Significantly less F4/80 was found in Pf-<i>mdx</i>/P2X7^−/− and G-<i>mdx</i>/P2X7^−/− muscles compared to <i>mdx</i> muscles (Kruskal-Wallis H test, <i>H</i> = 7.73, df = 2, <i>n</i> = 4, <i>p</i> = 0.021; Mann-Whitney U test, Pf-<i>mdx</i>/P2X7^−/− versus <i>mdx</i>, <i>W</i> = 26.0, <i>n</i> = 4, <i>p</i> = 0.030; G-<i>mdx</i>/P2X7^−/− versus <i>mdx</i>, <i>W</i> = 26.0, <i>n</i> = 4, <i>p</i> = 0.030), while the ratio of F4/80 level to CD163 level, denoting M1/M2 macrophage ratio, was significantly reduced in Pf-<i>mdx</i>/P2X7^−/− muscles (Kruskal-Wallis H test, <i>H</i> = 8.77, df = 2, <i>n</i> = 4, <i>p</i> = 0.012; Mann-Whitney U test, <i>W</i> = 26.0, <i>n</i> = 4, <i>p</i> = 0.030). (D) A representative Western blot (top) illustrating decreased P2RX4 protein levels, and corresponding qPCR data (bottom) showing decreased expression of P2RX4 mRNA in Pf-<i>mdx</i>/P2X7^−/− gastrocnemius compared to <i>mdx</i> gastrocnemius (ANOVA, <i>F</i> = 25.96, df = 2, <i>n</i> = 5, <i>p <</i> 0.001; Tukey’s test, <i>mdx</i> versus C57, <i>p <</i> 0.001; Pf-<i>mdx</i>/P2X7^−/− versus <i>mdx</i>, <i>p</i> = 0.017; Pf-<i>mdx</i>/P2X7^−/− versus WT, <i>p</i> = 0.005). …”

The effect of high CO₂ level on the pharynx requires HID-1 activity in the BAG neurons. by Kfir Sharabi (128721)

“…The CO₂ response is decreased after starvation. In all experiments <i>N</i>≥30 animals, except in panel C in <i>flp-17p</i>::HID-1::GFP (<i>N</i> = 5) and <i>gcy-33p</i>::HID-1::GFP (<i>N</i> = 10). …”

Synaptic plasticity and coincidence detection in the model Kenyon cell. by Luca A. Finelli (44577)

“…(F) Gaussian distributions of increasing width ( = 2×STD, abscissa) generated input trains of 10 spikes with decreasing probability of triggering a KC spike (see also [G]). …”

Table1_Effects of Several Organic Fertilizers on Heavy Metal Passivation in Cd-Contaminated Gray-Purple Soil.DOCX by Luyao Wang (3958562)

“…Organic fertilizer can not only improve soil quality and provide nutrients for plants but also reduce the harm of heavy metal ions to a certain extent, meaning it has become a current research hotspot in the field of heavy metal passivation. …”

Table2_Effects of Several Organic Fertilizers on Heavy Metal Passivation in Cd-Contaminated Gray-Purple Soil.XLSX by Luyao Wang (3958562)

“…Organic fertilizer can not only improve soil quality and provide nutrients for plants but also reduce the harm of heavy metal ions to a certain extent, meaning it has become a current research hotspot in the field of heavy metal passivation. …”

Case report: Nephrogenic adenoma of the urinary bladder by Alcides Chaux (554319)

“…Cords, individual cells, polypoid or papillary configurations and rare signet ring cell-like structures are identified in a decreasing proportion of cases. A distinguishing feature of nephrogenic adenoma is the presence of a thickened hyaline sheath around some of the tubules. …”

Magnetically-Propelled Fecal Surrogates for Modeling the Impact of Solid-Induced Shear Forces on Primary Colonic Epithelial Cells by Sam Hinman (8963249)

“…Protein secretion was modulated with a two-fold increase in luminal mucin-2 secretion and a significant reduction in basal interleukin-8 secretion. …”

Neutrophils attenuate inflammatory pain by local opioid peptide release. by Heike L. Rittner (265905)

“…<p>[A] In a rat model, inflammation was induced by intraplantar injection of heat-inactivated <i>Mycobacterium butyricum</i> (complete Freund's adjuvant). …”

Promoting Physical Activity in Patients with Colon Adenomas: A Randomized Pilot Intervention Trial by Kathleen Y. Wolin (152752)

“…<div><h3>Background</h3><p>Physical activity decreases risk of colon polyps and colon cancer and might reduce risk of colon cancer recurrence. …”

Supplemental Material for Liu, Ruediger, and Shapira, 2018 by Limeng Liu (5812814)

“…A. </b>Representative images of L3 <i>hsp-4p::gfp </i>transgenics, in a wildtype or <i>kgb-1 </i>genetic background, exposed to tunicamycin for 15 hours before imaging. …”

Comparative interaction study of elisidepsin and the plasma membrane of HCT-116 and HCT-116-Irv cells. by José Manuel Molina-Guijarro (814644)

“…<u>HCT-116-Irv cells treated with 5μM total elisidepsin</u> (FRET donor: Irv-OG488 200 nM, FRET acceptor: Irv-A555 800 nM, elisidepsin 3 μM, 1:4:15): Fluorescence intensity image <b>(D)</b>, FLIM-phasor image <b>(E)</b>, and the corresponding phasor plot <b>(F)</b> of representative elisidepsin treated HCT-116-Irv cells. …”