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66321
Percent of CSCs in MCF-7 human breast cancer cells treated with hyperthermia and metformin.
Published 2014“…<p>(A) Cells were incubated with 0–5 mM metformin for 48 h at 37°C, dispersed to single cells and analyzed for CD44<sup>high</sup>/CD24<sup>low</sup> cells (CSCs) with FACS. …”
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66322
Rer1 loss reduces γ-secretase activity, leading to abnormal Notch signaling and neural stem cell proliferation.
Published 2018“…(M) Light microscopy of neurospheres (secondary) derived from the cerebral cortex of control and forebrain specific Rer1 cKO mice on E14.5. Scale bar, 250 μm. (N) Mean values of secondary neurospheres formed by 200 dissociated cells from control and forebrain-specific Rer1cKO mice in 8 independent wells in a 96-well plate. …”
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66323
Time Course of BAD Phosphorylation during C. trachomatis or C. muridarum Infection
Published 2013“…<i>Chlamydia</i> infection at this MOI led to a decrease in the level of total BAD protein after 32 h of infection. …”
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66324
Androgen Receptor (AR) directly represses Sox2 expression in castration-resistant CWR-R1 cells.
Published 2013“…Levels at 0.5 hrs and beyond represent a statistically significant decrease in Sox2 mRNA (p<0.05). …”
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66325
Placental perfusion.
Published 2014“…In the microvillous and basal samples from control perfusions there was a decrease in GLUT1 relative to the expression prior to perfusion. …”
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66326
Model predictions for N vs. P limitation in the youngest Hawai’i and Franz Josef sites.
Published 2012“…Input and nutrient use efficiency parameters come from the 300 year old Hawaiian site (<i>I<sub>N</sub></i> = 9.6 kg N ha<sup>−1</sup> y<sup>−1</sup>, <i>I<sub>P</sub></i> = 0.63 kg P ha<sup>−1</sup> y<sup>−1</sup>, <i>ω<sub>N</sub> = </i>382 g C g N<sup>−1</sup>, <i>ω<sub>P</sub></i> = 6780 g C g P<sup>−1 </sup><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0042045#pone.0042045-Vitousek5" target="_blank">[37]</a>) and the 5–7 year old New Zealand site (<i>I<sub>N</sub></i> = 1.5 kg N ha<sup>−1</sup> y<sup>−1 </sup><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0042045#pone.0042045-Menge8" target="_blank">[78]</a>, <i>I<sub>P</sub></i> = 2.2 kg P ha<sup>−1</sup> y<sup>−1</sup>–calculated from the decrease in soil inorganic P from the 5 to the 60 year old site–<i>ω<sub>N</sub> = </i>45 g C g N<sup>−1</sup>, <i>ω<sub>P</sub></i> = 643 g C g P<sup>−1 </sup><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0042045#pone.0042045-Richardson1" target="_blank">[5]</a>), with the other parameters as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0042045#pone-0042045-g005" target="_blank">Fig. 5a</a>.…”
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66327
Addition of rSFRP4 results in MET in ovarian cancer cells.
Published 2013“…Results represent an average of 6 experiments and bars represent the s.d of the mean. **<i>P</i><0.01, ***<i>P</i><0.001. (<b>C</b>) Representative immunoblots showing increased CDH1, and decreased VIM and TWIST1 protein expression in OVCAR3 cells following 72 hours treatment with rSFRP4 (5 µg/ml). …”
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66328
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66329
GOAT MILK MANGO YOGHURTS: PHYSICOCHEMICAL STABILITY DURING OR STORAGE
Published 2018“…The aim of this study is to assess the stability of the procedure in the production of processed yogurt with goat milk and sleeve pulp. Five different yogurt formulations were processed using varying concentrations of sucrose (5, 10 and 15%) and mango pulp (4, 5 and 6%). …”
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66330
Prevalence of self-referred chronic pain and intercurrences in the health of the elderly
Published 2021“…CONCLUSION: Measures to decrease chronic pain in the elderly should be priority, especially in primary health attention services, because this is a multidimensional and complex public health problem.…”
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66331
Paradigm and results of Experiment 2: Unambiguous pre-exposure.
Published 2013“…<p><b>A</b>) The paradigm. The pre-exposure period had a fixed duration (4.3 minutes) and contained either an ambiguous globe, a globe disambiguated using binocular depth-cues (disparity) or a globe disambiguated using monocular depth-cues (contrast- and size-imbalance). …”
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66332
Inhibiting S6K1 does not alter pFMRP S499 levels <i>in vivo</i>.
Published 2014“…(<b>C</b>) Quantification verifies a significant decrease in pS6:S6 but no change in pFMRP:FMRP following mTORC1 or S6K1 inhibition <i>in vivo</i>. …”
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66333
Comparison between selecting mt protein-coding (PC) genes by individual gene performance vs. by length.
Published 2014“…<p>Utilizing the three mt protein-coding (PC) genes that individually performed “best” (based on <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0084080#pone-0084080-g003" target="_blank">Figure 3:</a> ND5, ND4, ND2), rather than the three longest (i.e, ND5, COX1, and ND4) mt PC genes, resulted in a significantly lower decrease in Ln <i>L</i> (± S.E.M.) compared to the “supergene” (i.e., all 13 mt PC genes) topology (<i>t</i>-test, <i>t</i> = 2.21, <i>df</i> = 1, 66, <i>P</i> = 0.03). …”
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66334
Characterization of urinary exosomes.
Published 2017“…Zetasizer analysis of urinary exosome samples (C). The results of the 5 measurements of the urine sample displayed in TEM (A) are shown (C, a). …”
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66335
Endocytosed albumin co-localized with lysosomes and was degraded in podocytes.
Published 2014“…<p>Confocal microscopy image demonstrating co-localization of albumin and lysosomes in a podocyte treated with 1.5 mg/mL FITC-albumin and Cathepsin B Magic Red for 1 hour. …”
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66336
Activated carbon loaded with manganese and iron for glyphosate adsorption: Kinetics, isotherms and thermodynamic studies
Published 2019“…Adsorption isotherm experiments were carried out at 5, 15, 25, 35 and 45°C. The adsorption isotherms presented a better fitting using the Freundlich model (R2>0.98), indicating a multilayer adsorption of glyphosate. …”
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66337
Kinetics of PfR6 interaction with HMG-box.
Published 2019“…Mixing the labeled protein with the probe-bound aptamer (green) resulted in a decrease of fluorescence over time, indicating that the binding of both components results in the quenching of fluorescein due to its vicinity with the quencher in the protein. …”
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66338
Simulation of [Mg<sup>2+</sup>]<sub>i</sub>–mediated changes of junctional conductance (black traces) measured in RIN cells expressing Cx36.
Published 2017“…The fitted junctional conductance (g<sub>j</sub>) kinetics (red trace) was obtained at ~4.5-fold V<sub>0</sub> increase and ~1000-fold p<sub>c1→c2</sub> decrease. …”
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66339
The Effect of p38MAPK on Cyclic Stretch in Human Facial Hypertrophic Scar Fibroblast Differentiation
Published 2013“…The fibroblasts were synchronized and randomly assigned to two groups: cyclic stretch and cyclic stretch pre-treated with SB203580 (a p38MAPK inhibitor). Cyclic stretch at 10% strain was applied at a loading frequency of 10 cycles per minute (i.e. 5 seconds of tension and 5 seconds of relaxation) for 0 h, 6 h and 12 h. …”
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66340
Homozygous <i>mray</i> mutants show severe craniofacial malformations starting early in development.
Published 2013“…<p><b>A, B,</b> Fluorescent images of a wild-type embryo compared to a homozygous <i>mray</i> littermate at E12.5. …”