Effect of serum lipoproteins on stereoselective halofantrine metabolism by rat hepatocytes by Patel, J. P.

“…Experimental hyperlipidemia has shown to decrease cytochrome P450 3A4 and 2C11 expression and to increase liver concentrations and the plasma protein binding of halofantrine (HF) enantiomers. …”
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Global Consumption Trend of Antifungal Agents in Humans From 2008 to 2018: Data From 65 Middle- and High-Income Countries by Pathadka, Swathi

“…Consumption of ketoconazole slowly declined, with 5.04% annual decrease, probably due to labelling changes in 2013 to reflect hepatotoxicity concerns. …”
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Effects of soaking, acidity and temperature on cadmium and lead removal from rice by Al-Naimi M.

“…Different rice treatments were involved i.e. three soaking times (0, 15, and 30 min), three temperatures (20, 25, and 30 �C) and four concentrations of glacial acetic acid (0.5%, 1%, 2%, and 3%). …”
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Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2. by P, Sneha

“…Molecular docking analysis revealed a decrease in interaction between the protein and ATP in all the 3 mutations, and molecular dynamic simulations of 50 ns showed a loss of stability and compactness in the mutant proteins. …”
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Differentiation of human olfactory bulb-derived neural stem cells toward oligodendrocyte. by Marei, Hany E

“…OBNSCs showed, after 5 days in OLs differentiation medium, a considerable decrease in the number of nestin positive cells, which was associated with a concomitant increase of NG2 immunoreactive cells and few O4(+)-OPCs. …”
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DC conductivity and Seebeck coefficient of nonstoichiometric MgCuZn ferrites by Madhuri, W.

“…Nonstoichiometric series of Mg0.5-xCuxZn0.5Fe1.9O4-? where x = 0.0, 0.1, 0.15, 0.2 and 0.25 has been synthesized by conventional solid state reaction route. …”
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STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS by AL-SADEQ, DUAA WALID

“…This study investigates the impact of five pathogenic CBS missense mutations [c.1006C>T (p.R336C), c.689T>A (p.L230Q), 215A>T (p.K72I), c.707C>A (p.T236N), and c.457G>A (p.G153R)] identified in homocystinuria patients and appeared to be resistant to pyridoxine treatment on the biochemical and biophysical properties of CBS protein. …”
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CLINICAL AND ECONOMIC IMPACT OF GENETIC AND NON-GENETIC FACTORS ON INR NORMALIZATION IN PRE-OPERATIVE MANAGEMENT OF WARFARIN PATIENTS by ELJILANY, ISLAM AHMED SAYED AHMED

“…To optimize the period of preprocedural warfarin interruption to decrease the incidence of bleeding in case of bridging and the incidence of thromboembolism in case of non-bridging, a study was conducted to determine the influence of CYP2C9, VKORC1, CYP4F2, FII, and FVII genetic polymorphisms and non-genetic factors on INR decline in a cohort of Arabs undergoing a procedure that requires warfarin interruption and developing an algorithm to tailor the duration of warfarin interruption before the procedure. …”
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Computational structural assessment of BReast CAncer type 1 susceptibility protein (BRCA1) and BRCA1-Associated Ring Domain protein 1 (BARD1) mutations on the protein-protein inter... by Thirumal Kumar, D.

“…From the analysis, we observed the highest deviation with lowest compactness and a decrease in the intramolecular h-bonds in the BRCA1-BARD1 protein complex with the V11G mutation compared to the native complex or the complexes with other mutations. 2022 Elsevier Inc.…”
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Study on adaptive thermal comfort in Japanese offices under various operation modes by Takasu, Marina

“…The lower and upper limits of the optimum comfort temperature is approximately 23.5C and 26.6C in mixed-mode. In addition, it is seen that the optimum comfort temperature tends to increase and decrease at very low and high outdoor air temperatures respectively. …”
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The effects of tart cherry juice with whey protein on the signs and symptoms of exercise-induced muscle damage following plyometric exercise by Hillman, Angela R.

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Effects of Climate and Atmospheric Nitrogen Deposition on Early to Mid-Term Stage Litter Decomposition Across Biomes by Kwon, Taeoh

“…We assessed how macroclimate and atmospheric inorganic N deposition under current and predicted scenarios (RCP 2.6, RCP 8.5) might affect litter mass loss measured after 3 and 12 months. …”
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Heat stress impairs proprioception but not running mechanics by Mtibaa K.

“…Methods 12 trained runners performed a proprioception test (active movement discrimination) before and immediately after a 30 min, self-paced treadmill run in HOT (39 °C) and COOL (22 °C) ambient conditions. …”
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Unveiling into Genetic Architecture of Transgenerational Stress Memory via Promoting Drought Tolerance in Barley by Alqudah, Ahmad M.

“…A significant quantitative trait nucleotide (QTN) at position 509,466,648 base pairs, has been identified in the candidate gene HORVU.MOREX.r3.5HG0502630. …”
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Biophysical studies of the effect of high power ultrasound on the DNA solution by Ali, Mohamed H.M.

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Investigation of optimal charging locations for electric vehicles in Istanbul by Atilgan, B.

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Understanding the mechanisms mediating cardio-renal benefit of empagliflozin in type 2 diabetes mellitus by Dimitrios, Patoulias

“…They have demonstrated1 that empagliflozin treatment resulted in a significant decrease in pulse pressure (PP), mean arterial pressure (MAP) and cardiac workload, compared with placebo; at week 12, placebo-adjusted mean changes from baseline were − 2.5 mmHg for PP, − 2.2 mmHg for MAP and − 315 mmHg x beats per minute (bpm) for cardiac workload (p < 0.0001 for all). …”
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Assessment of Urban Heat Islands Based on the Relationship Between Land Surface Temperature and Land Use/Land Cover in Greater Doha by Siddiqui, Simil Amir

“…The overall LST of greater Doha has increased by 0.7°C from 2000 to 2019. Furthermore %LULC of built up, vegetation, barren land, marsh land and water body were 29%, 4.5%, 58.6%, 2.8% and 5% in 2000 and 56.5 %, 8.2%, 33.2 %, 0% and 2.1% in 2019 respectively. …”
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Novel fluorinated surfactants for enhanced oil recovery in carbonate reservoirs by Al-Amodi, Adel O.

“…Both surfactants were found to be thermally stable at a high temperature (90 °C). Surfactant‐B decreased the viscosity and the storage modulus of the HPAM. …”
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Effect of left atrial ligation-driven altered inflow hemodynamics on embryonic heart development: clues for prenatal progression of hypoplastic left heart syndrome. by Salman, Huseyin Enes

“…According to our CFD analysis, LAL results in an immediate decrease in the left AV canal WSS levels for 3.5-day (HH21) pre-septated hearts. …”
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