CASP9 (caspase 9) is essential for autophagosome maturation through regulation of mitochondrial homeostasis by Hyun-Kyu An (498473)

“…</p> <p>AA: amino acid; ACD: autophagic cell death; ACTB: actin beta; ANXA5: annexin A5; APAF1: apoptotic peptidase activating factor 1; Atg: autophagy related; ATG16L1: autophagy related 16 like 1; BafA₁: bafilomycin A₁; BCL2: BCL2 apoptosis regulator; BECN1: beclin 1; CARD: caspase recruitment domain containing; CASP: caspase; CM-H₂DCFDA: chloromethyl-2ʹ,7ʹ-dichlorodihydrofluorescein diacetate; Δψm: mitochondrial membrane potential; DN: dominant-negative; DNM1L/DRP1: dynamin 1 like; EBSS: Earle’s balanced salt solution; GABARAP: GABA type A receptor-associated protein; GABARAPL1: GABA type A receptor associated protein like 1; GABARAPL2: GABA type A receptor associated protein like 2; HCN: hippocampal neural stem cells; IAM: inner autophagosome membrane; INS: insulin; KO: knockout; LEHD: Z-LEHD-fmk; MAP1LC3: microtubule associated protein 1 light chain 3; MFN1: mitofusin 1; MFN2: mitofusin 2; MTORC1: mechanistic target of rapamycin kinase complex 1; PARP1: poly(ADP-ribose) polymerase 1; PBS: phosphate-buffered saline; PE: phosphatidylethanolamine; ROS: reactive oxygen species; sgRNA: single guide RNA; SR-SIM: super-resolution structured illumination microscopy; SQSTM1: sequestosome 1; STS: staurosporine; STX17: syntaxin 17; TMRE: tetramethylrhodamine ethyl ester; TUBB: tubulin beta class I; ULK1: unc-51 like autophagy activating kinase 1; WT: wild type; ZFYVE1/DFCP1: zinc finger FYVE-type containing 1</p>…”

Additional file 1 of Characterisation of unessential genes required for survival under conditions of DNA stress by Hassan Ahmed Ezzat (8806121)

“…Additional file 1: Supplemental Figure S1 showing the comparison the adjusted relative quantity of RNA of strains carrying the V5 alleles. The figure shows the gradual decrease through graphical representation of the adjusted relative quantity between all the (A) Hip1-V5, (B) Swi1-V5, (C) Swi3-V5 and (D) Mrc1-V5 strains across the 24 hour timecourse after the addition of thiamine to the media.…”

Actin polymerization. by Angel Mozo-Villarías (646343)

“…The initial dimer formation suggests a decrease in the value of D as compared to those of the monomers. …”

<i>E. coli</i> 83972 attenuates NU14 bacteriuria. by Charles N. Rudick (143061)

“…<p>A) Experimental scheme for assessing efficacy of a single administration of ASB therapy relative to 3-day course of ciprofloxacin (n = 5 for all groups). …”

Simulations of multiple regulators (related to Fig 4). by Xiangrui Ji (16705908)

“…<p>(A) Given a fixed <i>θ</i>, <i>V</i>_<i>b</i> increases after deleting one activator and decreases after deleting one inhibitor. …”

State of the mixture distribution in response to an ABA- sequence, shown at several time points. by Dana Barniv (837537)

“…(b) This decrease causes <b><i>π</i>₂</b> to undergo a net increase. …”

Dynamic archaeal and bacterial OTUs within sediment slurry treatments. by Robert J. Martinez (150574)

“…Treatment conditions and total number of taxa plotted: (A) G2P (pH 5.5), (B) G3P (pH 5.5), (C) G2P (pH 6.8), and (D) G3P (pH 6.8). …”

Dynamic archaeal and bacterial OTUs within sediment slurry treatments. by Robert J. Martinez (150574)

“…Treatment conditions and total number of taxa plotted: (A) G2P (pH 5.5), (B) G3P (pH 5.5), (C) G2P (pH 6.8), and (D) G3P (pH 6.8). …”

SRMS accelerates ubiquitination of FKBP51 under nutrient-replete condition. by Jung Mi Park (5204840)

“…*nonspecific band. (<b>C</b>) WT SRMS or SRMS(K258A) mutant was expressed in SRMS KO U2OS cells. …”

Glutamate negatively influences THN migration. by Ulrike Theisen (4734555)

“…<p>(A) Following THNs along the MHB suggested a cell speed increase upon AMPA receptor block, whereas NMDA causes a speed decrease. …”

ndrg4 is required for sodium channel and neurofascin clustering in the peripheral nervous system. by Laura Fontenas (3371204)

“…Scale bars = 5 μm. (O,P) A significant decrease in the number of FIGQY labeled clusters is observed in ndrg4 mutants and morphants in comparison to controls (p<0.001).…”

G-CSF knockdown reduces MDSC accumulation. by Jeremy D. Waight (195980)

“…Splenocyte numbers were significantly higher (*<i>P</i><0.004) in the control compared to the G-CSF knockdown cohort (n = 5 mice each)<b>.</b> (<i>B</i>) Flow cytometric analysis of unfractionated splenocytes in panel <i>A</i> revealed a dramatic decrease in the percentage of CD11b⁺Gr-1⁺ cells in the control compared to the G-CSF knockdown cohort (n = 5 mice each). …”

Negative regulation of <i>sNPF/NPY</i> by insulin signaling. by Seung-Hyun Hong (136797)

“…<p>(A, B) Insulin treatment increased FoxO1 phosphorylation and decreased <i>NPY</i> expression in mouse hypothalamic GT1-7 cells while insulin with AKT inhibitor co-treatment slightly decreased FoxO1 phosphorylation and increased <i>NPY</i> expression. …”

Image_3_Is Penicillin Plus Gentamicin Synergistic Against Sessile Group B Streptococcal Isolates? An in Vivo Study With an Experimental Model of Foreign-Body Infection.TIF by Corinne Ruppen (5216951)

“…In a rat tissue cage model, we evaluated the efficacy of adjunctive gentamicin (GEN) administered systemically (5 mg/kg body weight) every 24 h, or locally (12.5 mg/L tissue cage concentration) every 24 or 72 h, in combination with penicillin (PEN) administered systemically (250,000 IU/kg body weight three times per day). …”

Image_1_Is Penicillin Plus Gentamicin Synergistic Against Sessile Group B Streptococcal Isolates? An in Vivo Study With an Experimental Model of Foreign-Body Infection.TIF by Corinne Ruppen (5216951)

“…In a rat tissue cage model, we evaluated the efficacy of adjunctive gentamicin (GEN) administered systemically (5 mg/kg body weight) every 24 h, or locally (12.5 mg/L tissue cage concentration) every 24 or 72 h, in combination with penicillin (PEN) administered systemically (250,000 IU/kg body weight three times per day). …”

Image_2_Is Penicillin Plus Gentamicin Synergistic Against Sessile Group B Streptococcal Isolates? An in Vivo Study With an Experimental Model of Foreign-Body Infection.TIF by Corinne Ruppen (5216951)

“…In a rat tissue cage model, we evaluated the efficacy of adjunctive gentamicin (GEN) administered systemically (5 mg/kg body weight) every 24 h, or locally (12.5 mg/L tissue cage concentration) every 24 or 72 h, in combination with penicillin (PEN) administered systemically (250,000 IU/kg body weight three times per day). …”

Image_4_Is Penicillin Plus Gentamicin Synergistic Against Sessile Group B Streptococcal Isolates? An in Vivo Study With an Experimental Model of Foreign-Body Infection.TIF by Corinne Ruppen (5216951)

“…In a rat tissue cage model, we evaluated the efficacy of adjunctive gentamicin (GEN) administered systemically (5 mg/kg body weight) every 24 h, or locally (12.5 mg/L tissue cage concentration) every 24 or 72 h, in combination with penicillin (PEN) administered systemically (250,000 IU/kg body weight three times per day). …”

Data_Sheet_1_Is Penicillin Plus Gentamicin Synergistic Against Sessile Group B Streptococcal Isolates? An in Vivo Study With an Experimental Model of Foreign-Body Infection.DOC by Corinne Ruppen (5216951)

“…In a rat tissue cage model, we evaluated the efficacy of adjunctive gentamicin (GEN) administered systemically (5 mg/kg body weight) every 24 h, or locally (12.5 mg/L tissue cage concentration) every 24 or 72 h, in combination with penicillin (PEN) administered systemically (250,000 IU/kg body weight three times per day). …”

Detection of methylation in promoter sequences by melting curve analysis-based semiquantitative real time PCR-3 by Aiala Lorente (88690)

“…Se and the decrease in the height of the specific peaks in the different percentages can be observed. …”

S1 Data - by Daniel Duane (18189603)

“…High frequency pulse train sounds from fish (0.5-1.5 kHz) are found to increase during moonlight hours, while low frequency fish vocalizations (0.1-0.3 kHz) and invertebrate sounds (2-20 kHz) are found to decrease during moonlight hours. …”