Cytoprotective gene regulation is essential to lifespan extension by diverse mechanisms. by David E. Shore (123998)

“…Lifespan was measured in three replicates comprising an average of 103 worms per condition. Data is presented as mean lifespan (columns 1–4), change mean lifespan in comparison to an empty vector RNAi control (column 5), or as the change in the extension of lifespan induced by each long-lived mutant (columns 6–8; for clarity, only decreases >15% are shown). …”

Exploiting Temporal Network Structures of Human Interaction to Effectively Immunize Populations by Sungmin Lee (166210)

“…<div><p>Decreasing the number of people who must be vaccinated to immunize a community against an infectious disease could both save resources and decrease outbreak sizes. …”

Spindle-F Is the Central Mediator of Ik2 Kinase-Dependent Dendrite Pruning in <i>Drosophila</i> Sensory Neurons by Tzu Lin (822560)

“…Spn-F acts downstream of IKK-related kinase Ik2 in the same pathway for dendrite pruning. Spn-F exhibits a punctate pattern in larval neurons, whereas these Spn-F puncta become redistributed in pupal neurons, a step that is essential for dendrite pruning. …”

Body Surface Potential Mapping during Ventricular Depolarization in Rats after Acute Exhaustive Exercise by Alexey G. Ivonin (13778765)

“…Also, compared with Pre-Ex, an increase in the amplitude of negative BSPM extremum at the R-wave peak on the ECG in lead II (RII-peak) and a decrease in the amplitude of negative BSPM extremum at 3 and 4 ms after RII-peak were showed at Post-Ex 5. …”

DataSheet1_Lycium barbarum polysaccharide reverses drug resistance in oxaliplatin-resistant colon cancer cells by inhibiting PI3K/AKT-dependent phosphomannose isomerase.PDF by Lijun Ma (207865)

“…However, the spleen index decreased in the OXA and LBP + OXA groups (p < 0.05), possibly as a side effect of oxaliplatin. …”

Impact of BCG vaccination on the repertoire of human gamma/delta T cell receptors (ms data) by Mei Xia (14585347)

DataSheet1_Biomass burning-agriculture coupling in the Orinoco savannas—Particulate matter emission scenarios.PDF by Rodrigo Jimenez (10999161)

Fixed and stained images of ß1-integrin and the membrane of C2C12 cells. by Daniel J. Modulevsky (307313)

“…However, after 60 min of CytD treatment a significant decrease in integrin-ß1 was observed, correlating to a significant decrease in cell adhesion strength (Fig. 5).…”

PDTC inhibits the <i>Nacrein</i> promoter activity. by Juan Sun (439334)

“…Increasing amounts of PDTC lead to a decrease in luciferase activity, suggesting a decrease in <i>Nacrein</i> promoter activity. …”

Data_Sheet_1_MicroRNA-29b-3p Promotes Human Retinal Microvascular Endothelial Cell Apoptosis via Blocking SIRT1 in Diabetic Retinopathy.pdf by Yong Zeng (203681)

“…To identify the regulating relationship between miR-29b-3p and SIRT1, HRMECs were transfected with miR-29b-3p mimics/inhibitors or their negative controls. SRT1720 was used as a SIRT1 agonist. Cell viability was assessed with the cell counting kit-8 (CCK-8) assay, and apoptotic cells were stained by one-step terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay kit. …”

Modulating the Coordination Environment of Cu-Embedded Mo<i>X</i>₂ (<i>X</i> = S, Se, and Te) Monolayers for Electrocatalytic Reduction of CO₂ to CH<sub>4</su... by Thamarainathan Doulassiramane (17382128)

“…Recently, single-atom catalysts (SACs) have attracted much attention in electrocatalysis and are more efficient than traditional metal-based catalysts. In this study, we modeled a Cu single atom embedded on Mo<i>X</i>₂ (<i>X</i> = Se and Te) monolayer with a single chalcogen (<i>X</i>) vacancy as SAC. …”

Adverse effect of ND251 aggregates on neurite outgrowth. by Huei-Ying Li (210957)

“…Cells expressing ND251S5A had a further decrease in the percentage of neurite-bearing cells in comparison with ND251. …”

Dysregulation of Cyclin B-associated proteins with loss of FlnB function. by Jianjun Hu (19574)

“…<p>(A) Flow cytometry following propridium iodide (PI) labeling demonstrates a decrease in the number of FlnBsh2 chondrocytes that reside in G2/M phase and an increase in the number of cells that reside in G1/G0 phase, compared to ATDC5 control cells. …”

Supplementary Material for: Nephrologist Interventions to Avoid Kidney Replacement Therapy in Acute Kidney Injury by Chávez-Íñiguez J.S. (11189730)

“…<b><i>Results:</i></b> From 2017 to 2020, we analyzed 288 AKI patients. The mean age was 55.3 years, 60.7% were male, AKI KDIGO stage 3 was present in 50.5% of them, sepsis was the main etiology 50.3%, and 72 (25%) patients started KRT. …”

Data_Sheet_1_Combined Carbon and Albedo Climate Forcing From Pine and Switchgrass Grown for Bioenergy.pdf by Benjamin J. Ahlswede (12539725)

“…We found that pine had a net positive radiative forcing (warming) of 5.4 ± 2.8 Wm⁻² when albedo and carbon were combined together (30 year mean). …”

Interaction of Ca²⁺ with the exit of proton channel H in bovine heart oxidase. by Tatiana Vygodina (456671)

“…Upon subsequent reduction of heme <i>a</i>, D51 undergoes reorientation associated with loss of the stabilizing hydrogen bonding to S^II205 and, hence, decreased proton affinity, so that its carboxylic group releases the proton to the <i>P</i>-phase (step <b><i>8</i></b>). …”

Subtropical high-montane forest climate refuges in Brazil by Guilherme Neto dos Santos (6721397)

“…The potential area of Crinodendron brasilense Reitz & L.B.Sm. decreased the most, by 82.11 % (RCP 4.5) and 90.06 % (RCP 8.5), respectively. …”

Reaching endpoints for lymphatic filariasis elimination- results from mass drug administration and nocturnal blood surveys, South Gujarat, India by Anjali Modi (3900520)

“…The current strategy to interrupt transmission of LF, is administration of once-yearly, single-dose, two-drug regimen (Albendazole with Diethylcarbamazine (DEC) to be used in endemic areas with the goal of reaching 65% epidemiological coverage for 4–6 years. We report findings of independent assessment from year 2010 to 2015 for last six rounds, after initial five rounds of Mass Drug Administration (MDA) since 2005 for ELF in endemic area of Gujarat.…”

Proxy FC provides limited explanatory power in understanding empirical FC patterns. by Michael Forrester (6165878)

“…FC proxies are computed via iterative linear combination of increasingly many eigenmode FC patterns, with accuracy measured after each subsequent addition; specifically: structural eigenvectors added at random (blue), according to the decreasing size of the corresponding eigenvalue (red), in an order chosen for which the step-wise decrease in error is maximised (orange); and eigenmodes of the network Jacobian, in order of decreasing size of the corresponding eigenvalue (purple). …”

Insight into Temperature Dependence of GTPase Activity in Human Guanylate Binding Protein-1 by Anjana Rani (151827)

“…The hydrolysis reaction in hGBP1 is believed to involve with a number of catalytic steps. To investigate the effect of temperature in the product formation and on the different catalytic complexes of hGBP1, we carried out temperature dependent GTPase assays, mutational analysis, chemical and thermal denaturation studies. …”