Image_2_Dupilumab improves clinical symptoms in children with Netherton syndrome by suppressing Th2-mediated inflammation.jpg by Shi Yan (164233)

“…Skin barrier dysfunction caused by SPINK5 gene mutations is a hallmark of the disease. …”

Image_3_Dupilumab improves clinical symptoms in children with Netherton syndrome by suppressing Th2-mediated inflammation.jpeg by Shi Yan (164233)

“…Skin barrier dysfunction caused by SPINK5 gene mutations is a hallmark of the disease. …”

Identification of whole blood mRNA and microRNA biomarkers of tissue damage and immune function resulting from amphetamine exposure or heat stroke in adult male rats by Luísa Camacho (5508251)

“…Most transcripts specific for T-cells decreased 50–70% after AMPH exposure or EIH, with the noted exception of <i>Ccr5</i> and <i>Chst12</i>. …”

Phenotypes of the shACADS and shNTC knockdown Huh7 cells. by Kerstin Matejka (6729155)

“…<p>Doxycycline-induced knockdown of ACADS resulted in a long-term decrease of protein abundance and mRNA expression, and an intracellular accumulation of C4-acylcarnitine, which reflects the ACADS substrate C4-CoA. …”

Colon microbiome. by Ditte Olsen Lützhøft (10837857)

APOBEC3A and APOBEC3B are differentially inhibited by RNA. by Luis M. Cortez (8129835)

“…Prior to incubating the extracts with the hairpin DNA substrate, extracts where either mock-treated or treated with 2.5 μM RNaseA at 37°C for 30 min. (B) Coomassie stained SDS-PAGE showing the purity of A3A (23 kDa) and A3B (42 kDa) over-expressed in and purified from HEK293T cells. …”

Genome Scan for Selection in Structured Layer Chicken Populations Exploiting Linkage Disequilibrium Information by Mahmood Gholami (553033)

“…We found a total of 41 and 107 regions with outstanding differentiation or similarity using hapFLK and its single SNP counterpart FLK respectively. …”

Six-fold Oxygen-Coordinated Triplet (<i>S</i> = 1) Palladium(II) Moieties Templated by Tris(bipyridine)ruthenium(II) Ions by Fabrice Pointillart (1593232)

“…These techniques reveal an unusual 6-fold oxygen environment around the Pd(II) atoms with two short (2.02 Å) and four long (2.17 Å) Pd−O distances. As stated by magnetometry, this environment is associated with a triplet ground state (<i>S</i> = 1) of the palladium(II) ion:  when the temperature is decreased, the χ_M<i>T</i> product shows a monotonous decrease from 5.54 cm³ K mol^-1 at 300 K, a value which is slightly lower than the one expected for independent paramagnetic Pd(II) (<i>S</i> = 1, <i>g</i> = 2) and Mn(II) (<i>S</i> = ⁵/₂, <i>g</i> = 2) ions. …”

Six-fold Oxygen-Coordinated Triplet (<i>S</i> = 1) Palladium(II) Moieties Templated by Tris(bipyridine)ruthenium(II) Ions by Fabrice Pointillart (1593232)

“…These techniques reveal an unusual 6-fold oxygen environment around the Pd(II) atoms with two short (2.02 Å) and four long (2.17 Å) Pd−O distances. As stated by magnetometry, this environment is associated with a triplet ground state (<i>S</i> = 1) of the palladium(II) ion:  when the temperature is decreased, the χ_M<i>T</i> product shows a monotonous decrease from 5.54 cm³ K mol^-1 at 300 K, a value which is slightly lower than the one expected for independent paramagnetic Pd(II) (<i>S</i> = 1, <i>g</i> = 2) and Mn(II) (<i>S</i> = ⁵/₂, <i>g</i> = 2) ions. …”

Economic evaluation of brief cognitive behavioural therapy for social activation in recent-onset psychosis by Ben F. M. Wijnen (4997315)

“…Treatment response rate (i.e. ≥ 5-point decrease on the PANSS) was not significantly different. …”

A: Number of type II cells per lung by Lars Knudsen (36605)

Image_1_Silencing Long Non-coding RNA Kcnq1ot1 Limits Acute Kidney Injury by Promoting miR-204-5p and Blocking the Activation of NLRP3 Inflammasome.tiff by JunTao Wang (11679331)

“…<p>Acute kidney injury (AKI) is a critical clinical disease characterized by an acute decrease in renal function. …”

Involvement of mitochondrial pathway in AG–4 induced apoptosis. by Deepak Kumar (63095)

“…<p>(A) Loss of mitochondrial membrane potential. Cells were incubated with AG–4 (5.4 μM, 0–48 h) and loaded with JC–1 for flow cytometric analysis of mitochondria transmembrane potential. …”

Table_1_Benefit of Physiologically Variable Over Pressure-Controlled Ventilation in a Model of Chronic Obstructive Pulmonary Disease: A Randomized Study.DOCX by Andre Dos Santos Rocha (9980156)

“…Animals ventilated with the variable mode also presented less lung derecruitment (decrease in lung aerated area, –3.4 ± 9.9 versus –17.9 ± 6.7%, p < 0.01) and intrapulmonary shunt fraction (9.6 ± 4.1 versus 17.0 ± 5.8%, p < 0.01).…”

<i>Porphyromonas gingivalis</i> Evasion of Autophagy and Intracellular Killing by Human Myeloid Dendritic Cells Involves DC-SIGN-TLR2 Crosstalk by Ahmed R. El-Awady (697683)

“…We employed a panel of <i>P. gingivalis</i> isogenic fimbriae deficient strains with defined defects in Mfa-1 fimbriae, a DC-SIGN ligand, and FimA fimbriae, a TLR2 agonist. …”

Endogenous small interfering RNAs associated with maize embryonic callus formation by Fei Ge (686121)

“…In addition, certain genes related to auxin transport and stem cell or meristem development (e.g., <i>PLT5-like</i>, <i>ARF15</i>, <i>SAUR-like</i>, <i>FAS1-like</i>, <i>Fea3</i>, <i>SCL5</i>, and <i>Zmwox2A</i>) were regulated by the differentially expressed siRNAs. …”

Table_1_Ma Xing Shi Gan Decoction Attenuates PM2.5 Induced Lung Injury via Inhibiting HMGB1/TLR4/NFκB Signal Pathway in Rat.docx by Yu-xiang Fei (7862660)

“…In this study, rats were stimulated with PM2.5 to induce lung injury. MXD was given orally once daily for five days. …”

Recognition of HBV-infected cells by TCR-transduced T cells. by Karin Wisskirchen (4339774)

“…<p>(A) Expression of HLA-A*02 on HepaRG target cells determined by flow cytometry. …”

Lithium Polyniobates. A Lindqvist-Supported Lithium−Water Adamantane Cluster and Conversion of Hexaniobate to a Discrete Keggin Complex by Travis M. Anderson (2069068)

“…The reaction of Li₇K[Nb₆O₁₉]·15H₂O and Si(OC₂H₅)₄ yields Li₁₃K[SiNb₁₂(OH)₂O₃₈]·17H₂O (<i>a</i> = 20.341(4) Å, <i>b</i> = 10.735(2) Å, <i>c</i> = 21.438(4) Å, β = 105.41(3)°, monoclinic, <i>P</i>2₁/<i>c</i>, R1 = 6.49% based on 6161 reflections), an α-Keggin ion ([SiNb₁₂(OH)₂O₃₈]^14-) linked by Li⁺ cations and a single K⁺ cation. …”

Lithium Polyniobates. A Lindqvist-Supported Lithium−Water Adamantane Cluster and Conversion of Hexaniobate to a Discrete Keggin Complex by Travis M. Anderson (2069068)

“…The reaction of Li₇K[Nb₆O₁₉]·15H₂O and Si(OC₂H₅)₄ yields Li₁₃K[SiNb₁₂(OH)₂O₃₈]·17H₂O (<i>a</i> = 20.341(4) Å, <i>b</i> = 10.735(2) Å, <i>c</i> = 21.438(4) Å, β = 105.41(3)°, monoclinic, <i>P</i>2₁/<i>c</i>, R1 = 6.49% based on 6161 reflections), an α-Keggin ion ([SiNb₁₂(OH)₂O₃₈]^14-) linked by Li⁺ cations and a single K⁺ cation. …”