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64981
Targeted deletion of PPARγin macrophages inhibits lung cancer metastasis in an orthotopic mouse model of non-small cell lung cancer.
Published 2011“…Animals were injected with 10<sup>5</sup> CMT/167-luc cells orthotopically as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0028133#pone-0028133-g001" target="_blank">Fig. 1</a>. …”
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64982
Schematic representation of the possible effects of PARP-1 activation on mTORC1 and mTORC2 components and cell death.
Published 2012“…PAR transiently accumulates and its metabolism results in a decrease in ATP and NAD<sup>+</sup> levels, while cellular AMP increases concomitantly. …”
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64983
Comprehensive transcriptome analysis and flavonoid profiling of Ginkgo leaves reveals flavonoid content alterations in day–night cycles
Published 2018“…A detailed analysis of individual flavonoids showed that most of their contents were decreased by various degrees. …”
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64984
Example of the rules involved in Collagen 1 turnover.
Published 2024“…<p><b>A</b>), Decrease of collagen degradation, the value of <i>token COL</i>1_<i>remodeling</i>_<i>high</i> is decreased and that of <i>COL</i>1_<i>remodeling</i>_<i>low</i> is increased; <b>B</b>), Production of collagen by activated HSCs, the rate of application of the rule is proportional to the value of <i>counter intermediate</i>_<i>step</i>. …”
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64985
Impaired insulin release, mitochondrial function and Ca<sup>2+</sup> handling in islets with short telomeres.
Published 2011“…<b>C</b>. Data are means of decrease in % rhodamine 123 fluorescence normalized to carbonyl cyanide 4-(trifluoro-methoxy) phenylhydrazone (FCCP) depolarization. …”
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64986
Supplementary Materials
Published 2022“…The relationship between PA and psychological and behavioral problems and changes in PA, QoL, and sleeping patterns before and during the pandemic in preschoolers, children, and adolescents were investigated. A meta-analysis was conducted; odds ratios (ORs), mean differences (MD), and standardized MDs (SMDs) were calculated. …”
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64987
Preventable deaths in childhood, according to actions of the Unified Health System, Brazil
Published 2019“…Results: In Brazil, preventable death rates (5.1% per year) had a higher decrease compared with non-preventable ones (2.5% per year). …”
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64988
Myelin alteration in 8-week-old TRAF4-KO mice.
Published 2013“…(C): Western blot analysis of the myelin-specific MBP marker and of the interglial-specific TJ marker claudin 11 (cl 11) showed a decreased expression level of both proteins in 4 independent TRAF4-KO cerebellum protein extracts (lanes 5–8) compared with 4 WT samples (lanes 1–4) ; tubulin served as a loading control. …”
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64989
DataSheet_1_GMP-Compliant Manufacturing of TRUCKs: CAR T Cells targeting GD2 and Releasing Inducible IL-18.pdf
Published 2022“…Manufactured TRUCKs showed a specific cytotoxicity towards GD<sub>2</sub>-expressing target cells indicated by lactate dehydrogenase (LDH) release, a decrease of target cell numbers, microscopic detection of cytotoxic clusters and detachment of target cells in real-time impedance measurements (xCELLigence). …”
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64990
p21 is regulated by AR and required for cellular senescence.
Published 2012“…Tubulin was used as a loading control (A). Note the decrease in Rb phosphorylation and p21 increase in DHT-treated cells at every time point. …”
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64991
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64992
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64993
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64994
Evolutionary Conservation and Diversification of Puf RNA Binding Proteins and Their mRNA Targets
Published 2015“…Focusing on Puf proteins and their targets across 80 fungi, we constructed a parsimonious model for their evolutionary history. …”
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64995
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64996
DataSheet1_Characteristics of adverse reactions of three anti-glioma drugs in WHO-VigiAccess.ZIP
Published 2024“…The analysis revealed that the ten most frequently reported AEs included bone marrow suppression, myalgia, leukopenia, thrombocytopenia, nausea, vomiting, death, rhabdomyolysis, disease progression, and a decrease in neutrophil count. The five most common categories of AEs related to anti-glioma drugs were blood and lymphatic system diseases (20,233 cases, 15.2%), general disorders and administration site conditions (26,973 cases, 20.3%), gastrointestinal dysfunction (22,061 cases, 16.7%), necessitating further investigations (18,285 cases, 13.8%), and musculoskeletal and connective tissue diseases (30,695 cases, 23.1%). …”
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64997
Early blockade of CB1 and/or CB2 receptors reduces the density of serotonergic fibres below the lesion site.
Published 2013“…(E) Quantification of the area occupied by serotonin shows a significant decrease in AM630- and AM281/AM630-treated rats and a strong trend to decrease in AM281-treated rats, that is close to statistical significance (p = 0.06). …”
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64998
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64999
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65000