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Image_2_IL-1β enhances cell viability and decreases 5-FU sensitivity in novel colon cancer cell lines derived from African American patients.tif
Published 2022“…When compared to Caucasian American (CA) patients, AAs also have reduced response to the first line standard of care chemotherapeutic agent 5-Fluorouracil (5-FU). Previously, we observed differential gene expression between the two populations, suggesting that colon tumors from AA patients display a decreased antitumor immune response and an increased expression of genes encoding proteins involved in inflammatory processes, such as Interleukin-1β (IL-1β). …”
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Decreased bleomycin-induced apoptosis in hTERT transfected MLE cells.
Published 2015“…(B) Flow cytometry analysis demonstrating decreased Annexin V staining in bleomycin-treated hTERT<sup>+</sup> compared to hTERT<sup>ctrl</sup> cells. …”
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DataSheet_1_Failure to decrease HbA1c levels following TB treatment is associated with elevated Th1/Th17 CD4+ responses.pdf
Published 2023“…</p>Results<p>CD62 P-selectin was up- (1.5-fold) and IL-10 downregulated (0.85-fold) in plasma among individuals whose HbA1c remained stable/increased during TB treatment. …”
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Image_10_Consecutive Hypoxia Decreases Expression of NOTCH3, HEY1, CC10, and FOXJ1 via NKX2-1 Downregulation and Intermittent Hypoxia-Reoxygenation Increases Expression of BMP4, NOTCH1, MKI67, OCT4, and MUC5AC via HIF1A Upregulation in Human Bronchial Epithelial Cells.tif
Published 2020“…Inhibition of HIF1A or NKX2-1 expression by siRNA transfection respectively decreased BMP4/NOTCH1/MKI67/OCT4/MUC5AC and NOTCH3/HEY1/CC10/FOXJ1 expression in the HBE cells cultured under intermittent H/R to the same levels under normoxia. …”
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VRK1 overexpression is seen in human breast cancer and is associated with decreased relapse-free survival.
Published 2018“…The overall median rank of VRK1 mRNA overexpression was 947 (out of 19,273 measured genes) (p = 3.64x10<sup>-28</sup>). Data for cancer subtypes are shown in boxes numbered 1–11: 1: benign breast neoplasm (rank 6459, 1.4 fold-change, NS), 2: breast carcinoma (rank 833, 1.5 fold-change, p = 3.83x10<sup>-5</sup>), 3: breast phyllodes tumor (rank 512, 1.2 fold-change, p = 0.002), 4: ductal breast carcinoma in situ (rank 1969, 1.5 fold-change, p = 0.002), 5: invasive breast carcinoma (rank 1060, 1.6 fold-change, p = 1.28x10<sup>-5</sup>), 6: invasive ductal and invasive lobular breast carcinoma (rank 941, 1.5 fold-change, p = 6.76x10<sup>-22</sup>), 7: invasive ductal breast carcinoma (rank 613, 1.5-fold change, p = 2.71x10<sup>-71</sup>), 8: invasive lobular breast carcinoma (rank 947, 1.3 fold-change, p = 3.64x10<sup>-28</sup>), 9: medullary breast carcinoma (rank 400, 1.8 fold-change, p = 3.25x10<sup>-12</sup>), 10: mucinous breast carcinoma (rank 1932, 1.4 fold-change, p = 7.41x10<sup>-10</sup>) and 11: tubular breast carcinoma (rank 1253, 1.4 fold-change, p = 1.24x10<sup>-17</sup>). …”
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Forty-two receptors arranged in order of decreasing interaction with the full set of thirty-five drugs.
Published 2010“…<p>The forty-two receptors are arranged in order of decreasing interaction with the full set of thirty-five drugs, based on the breadth statistics, B, B<sub>sq</sub>. and B<sub>exp</sub>. …”
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Aged blood factors decrease cellular responses associated with delayed gingival wound repair
Published 2017“…<div><p>Aging is a gradual biological process characterized by a decrease in cell and organism functions. …”
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Complete data.
Published 2024“…A tenfold decrease or increase in concentration induced only a 2-fold decrease or increase in clot degradation. …”
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Fig 4 -
Published 2024“…A tenfold decrease or increase in concentration induced only a 2-fold decrease or increase in clot degradation. …”