PLD inhibitors decrease PLD2 expression in foci of lungs following xenotransplantation. by Karen M. Henkels (3350273)

“…<p>(<b>A</b>) Primary tumor volume from xenotransplanted mice in the presence or absence (“control” = vehicle only) of PLD inhibitors delivered by Alzet pumps, as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0166553#pone.0166553.g001" target="_blank">Fig 1</a> legend. …”

Intervention with MLKL decreased neutrophil death and protected mice against <i>E. coli</i> pneumonia. by Qinyu Luo (13000956)

Simulated effects of increased pCREB combined with decreased pCaMKIIα on bistability. by Yili Zhang (540283)

“…<p>(A1) Modification of model. Increased basal phosphorylation of CREB <i>k</i>_{<i>basalp_creb</i>}, concurrent with decreased basal phosphorylation of CaMKIIα <i>k</i>_{<i>basalp_CaMKII</i>}, in the absence of the effects of MeCP2/HDAC2/Sin3a (red) ([<i>E</i>_<i>comp</i>] = 0; [<i>E</i>_<i>MeCP2</i>] = 0). …”

Muscle-specific knockdown of <i>nSMase</i> decreases a subset of ceramide species that are decreased in <i>Gba1b</i> mutants. by Kathryn A. Jewett (3756811)

HDM-specific IgE levels decreased in response to TSLPR ablation in chronic model of asthma mice. by Latifa Koussih (326043)

Decreased E/I synapse ratio and loss of cortico-LA synaptic plasticity in the absence of coronin 1. by Rajesh Jayachandran (542641)

“…Scale bars, 2 mV and 10 ms. (F) Cortico-LA LTP is completely absent in coronin 1–deficient mice (red symbols). …”

Variants enriched in an <i>Ae</i>. <i>aegypti</i> cell line <i>(</i>Aag2) have increased fitness in Aag2 cells but decreased fitness in a human cell line (MRC-5). by Chelsea Cereghino (15188341)

Activation of GluR5 increased neuronal excitability in interneruons but decreased excitability in pyramidal neurons. by Long-Jun Wu (47043)

“…Resting membrane potential for this neuron was −66.6 mV and the holding current was 66.9 pA. (H) Pooled data showed that ATPA (3 µM) increased firing rate of interneurons (n = 6) while decreased that of pyramidal neurons (n = 5). …”

ApoER2 expression increases Aβ production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of γ-secretase activity-5 by Rodrigo A Fuentealba (77901)

“…<p><b>Copyright information:</b></p><p>Taken from "ApoER2 expression increases Aβ production while decreasing Amyloid Precursor Protein (APP) endocytosis: Possible role in the partitioning of APP into lipid rafts and in the regulation of γ-secretase activity"</p><p>http://www.molecularneurodegeneration.com/content/2/1/14</p><p>Molecular Neurodegeneration 2007;2():14-14.…”

Three variants lower the rheobase and increase firing frequency of Ca_V3.3, while the A398V variant shows the opposite effect. by Yousra El Ghaleb (22075892)

Subjects:

All-Atom Simulations Reveal the Effect of Membrane Composition on the Signaling of the NKG2A/CD94/HLA‑E Immune Receptor Complex by Martin Ljubič (15680161)

“…Additionally, we found that a large concentration of negative charge at the surface of the POPA-based membrane greatly increased the number of contacts with lipid molecules and significantly decreased the exposure of intracellular NKG2A ITIM regions to water molecules, thus likely halting the signal transduction process. …”

Decreased tumorigenicity of A549 cells <i>in vivo</i> with reduced IQGAP3 expression. by Ying Yang (24175)

<i>Cbp</i> inhibition decreases hypothalamic glycolytic markers. by Cesar L. Moreno (3341927)

NEURON computer model. by Yousra El Ghaleb (22075892)

Subjects:

Window current properties. by Yousra El Ghaleb (22075892)

Subjects:

Activation gating properties of <i>CACNA1I</i> variants. by Yousra El Ghaleb (22075892)

Subjects:

Decrease in levels of <i>Sox2</i> expression delays prosensory specification. by Lu M. Yang (6919364)

HA-MAD1 tumors have increased CIN and decreased p53. by Sarah E. Copeland (13951506)

Loss of nsp14-ExoN activity decreases recombination frequency and alters recombination junction patterns across the genome. by Jennifer Gribble (10005444)

TG mice hearts show decreased ISO response. by Mayilvahanan Shanmugam (691549)