Image_2_Tocilizumab (TCZ) Decreases Angiogenesis in Rheumatoid Arthritis Through Its Regulatory Effect on miR-146a-5p and EMMPRIN/CD147.jpeg by Devy Zisman (11838428)

“…In vitro, the accumulation in the supernatants of the pro-angiogenic factors EMMPRIN, VEGF and MMP-9 was increased by co-culturing the HT1080 fibroblasts and the U937 monocytes, while the accumulation of the anti-angiogenic factor thrombospondin-1 (Tsp-1) and the expression levels of miR-146a-5p were reduced. Transfection of HT1080 cells with the miR-146a-5p mimic, decreased the accumulation of EMMPRIN, VEGF and MMP-9. …”

Image_1_Tocilizumab (TCZ) Decreases Angiogenesis in Rheumatoid Arthritis Through Its Regulatory Effect on miR-146a-5p and EMMPRIN/CD147.jpeg by Devy Zisman (11838428)

“…In vitro, the accumulation in the supernatants of the pro-angiogenic factors EMMPRIN, VEGF and MMP-9 was increased by co-culturing the HT1080 fibroblasts and the U937 monocytes, while the accumulation of the anti-angiogenic factor thrombospondin-1 (Tsp-1) and the expression levels of miR-146a-5p were reduced. Transfection of HT1080 cells with the miR-146a-5p mimic, decreased the accumulation of EMMPRIN, VEGF and MMP-9. …”

Use of Oral Bisphosphonates in Primary Prevention of Fractures in Postmenopausal Women: A Population-Based Cohort Study by Jordi Real (720621)

“…</p><p>Setting</p><p>Women aged 60 years and older in 2005, from 21 primary care centers in a healthcare region of Spain.</p><p>Participants</p><p>Two groups of women aged 60 years and older (n = 1208), prescribed either calcium and vitamin D (CalVitD) or bisphosphonates (BIPHOS) with or without calcium and vitamin D, were compared for the end point of first recorded osteoporotic-related fracture, with 5-years follow-up.…”

Colored points represent the dates where events from Fig 7, have a <i>p</i>-value below the <i>α</i> = 0.05 significance level, i.e. dates where the statistical behavior of the dur... by Héctor Raúl Olivares-Sánchez (13014866)

Mean decrease in accuracy (MDA) of top 15 urine metabolites. by Liam E. Broughton-Neiswanger (8447220)

“…Urine metabolites with a mean decrease in accuracy ≥ 0.004 in at least one post-treatment time point (2–5) were considered for inclusion in the predictive model.…”

5-hmC is increased during THP1 macrophage differentiation. by Fangfang Sun (2410654)

Image_1_miR-144-5p and miR-451a Inhibit the Growth of Cholangiocarcinoma Cells Through Decreasing the Expression of ST8SIA4.tif by Wan Fu (3681799)

“…This study aimed to investigate the action mechanism of miR-144-5p and miR-451a in cholangiocarcinoma. We found that miR-144-5p and miR-451a were significantly decreased in cholangiocarcinoma patient samples compared to the adjacent normal bile duct samples. …”

Image_4_miR-144-5p and miR-451a Inhibit the Growth of Cholangiocarcinoma Cells Through Decreasing the Expression of ST8SIA4.tif by Wan Fu (3681799)

“…This study aimed to investigate the action mechanism of miR-144-5p and miR-451a in cholangiocarcinoma. We found that miR-144-5p and miR-451a were significantly decreased in cholangiocarcinoma patient samples compared to the adjacent normal bile duct samples. …”

Image_3_miR-144-5p and miR-451a Inhibit the Growth of Cholangiocarcinoma Cells Through Decreasing the Expression of ST8SIA4.tif by Wan Fu (3681799)

“…This study aimed to investigate the action mechanism of miR-144-5p and miR-451a in cholangiocarcinoma. We found that miR-144-5p and miR-451a were significantly decreased in cholangiocarcinoma patient samples compared to the adjacent normal bile duct samples. …”

Image_2_miR-144-5p and miR-451a Inhibit the Growth of Cholangiocarcinoma Cells Through Decreasing the Expression of ST8SIA4.tif by Wan Fu (3681799)

“…This study aimed to investigate the action mechanism of miR-144-5p and miR-451a in cholangiocarcinoma. We found that miR-144-5p and miR-451a were significantly decreased in cholangiocarcinoma patient samples compared to the adjacent normal bile duct samples. …”

AMS scores decrease over three days at high-altitude. by Erica C. Heinrich (6832055)

Cancer drugs that decrease cardiomyocyte viability induce cellular stress. by E. Renee Matthews (18071587)

Interactions between E1A and PKA are required for full HAdV-5 progeny production. by Cason R. King (2633092)

“…Growth of WT virus was decreased by knockdown of each PKA subunit. Growth of HAdV E1A Δ4–25 was not affected by knockdown of PKA regulatory subunits, but was affected by knockdown of PKA Cα (though to a lesser extent than WT HAdV-5). …”

In the absence of chloride, two-fold decrease in [Na⁺]_e shifted GLT-1a E_rev by −28 mV at both low and high glutamate concentrations. by Anatoli Y. Kabakov (729047)

“…<b>(B)</b> Representative data show total membrane current, the time courses of [Na⁺]_e, [Glu^-]_e, and [DHK]_e at the top, and HP voltage ramps (–100 to +20 mV) at the bottom. Arrow head points to simultaneous decrease in [Glu^-]_e and [Na⁺]_e, which affects the current. …”

miR-200b is sufficient to decrease tumor growth. by LaTanya V. Williams (504683)

“…(G, H) Tumor sections were stained for Ki-67, to evaluate proliferation. Note a significant decrease in Ki-67–positive nuclei in the presence of miR-200b. *, p<0.001.…”

LGP2 deficiency decreases intracellular dsDNA signaling. by Darja Pollpeter (353259)

NETs decrease <i>T</i>. <i>cruzi</i> infectivity. by Daniel Sousa-Rocha (802734)

() Increase and decrease of fly gene transcript levels during embryogenesis by Sean D Hooper (55379)

Plakoglobin decreases <i>in vitro</i> cell growth and proliferation. by Zackie Aktary (481667)

Topical application of ATX inhibitor (S32826) decreases IOP in rabbits. by Padma Iyer (141117)

“…<p>Topical application of S32826 (dissolved in water, pH∼8–9) decreased IOP in a dose- and time- dependent manner in Dutch-Belted adult male rabbits, as determined using pneumotonometer under waking conditions. …”