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201
Decreased Polycystin 2 Levels Result in Non-Renal Cardiac Dysfunction with Aging
Published 2016“…Here, we examined 1 and 9 month old Pkd2+/- mice to determine if decreased amounts of functional polycystin 2 leads to impaired cardiac function with aging. …”
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Earlier Migration Timing, Decreasing Phenotypic Variation, and Biocomplexity in Multiple Salmonid Species
Published 2013“…<div><p>Climate-induced phenological shifts can influence population, evolutionary, and ecological dynamics, but our understanding of these phenomena is hampered by a lack of long-term demographic data. We use a multi-decade census of 5 salmonid species representing 14 life histories in a warming Alaskan stream to address the following key questions about climate change and phenology: How consistent are temporal patterns and drivers of phenology for similar species and alternative life histories? …”
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Supplementary Material for: SGLT2 inhibitors decrease overhydration and proteasuria in patients with chronic kidney disease: a longitudinal observational study
Published 2024“…Results: 42 patients (29 % with diabetic/hypertensive CKD, 31 % with IgA nephropathy; 88 % dapagliflozin 10 mg, 10 % dapagliflozin 5 mg, 2 % empagliflozin 20 mg; median eGFR 46 mL/min/1.73m² and albuminuria 1911 mg/g creatinine) participated in the study. …”
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Supplementary Material for: SGLT2 inhibitors decrease overhydration and proteasuria in patients with chronic kidney disease: a longitudinal observational study
Published 2024“…Results: 42 patients (29 % with diabetic/hypertensive CKD, 31 % with IgA nephropathy; 88 % dapagliflozin 10 mg, 10 % dapagliflozin 5 mg, 2 % empagliflozin 20 mg; median eGFR 46 mL/min/1.73m² and albuminuria 1911 mg/g creatinine) participated in the study. …”
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206
Decreased reactive gliosis following ES delivered 5d post-demyelination.
Published 2014“…Contralateral intact control nerves displayed only minimal GFAP IF (A). However 5d post-lysophosphatidyl choline (LPC)/FG injection there was a marked increase in GFAP IF (B). …”
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Api5 depletion induces a decrease in E2F1-target gene mRNA levels without affecting E2F1 expression.
Published 2013“…<p><b>A.</b> Api5 and E2F1 reciprocal regulation. After depletion of Api5 and E2F1 with specific siRNAs, H1299 cells were made quiescent by serum starvation for 48 h (0% FBS) and then allowed to progress through the cell cycle over 10 hours by FBS addition (10 h refeeding). …”
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Supplementary Material for: Kidney and cardiovascular outcomes in older population with mildly to moderately decreased kidney function - A nationwide cohort study
Published 2024“…Mildly to moderately decreased eGFR was associated with a higher risk of kidney failure, CVD, and all-cause death compared with eGFR 60–89 ml/min/1.73 m2 in the old and very old groups, regardless of proteinuria (adjusted hazard ratio [95% confidence interval] in the very old group without proteinuria: kidney failure 3.048 [2.495–3.722], CVD 1.103 [1.066–1.142], and all-cause death 1.172 [1.144–1.201]). …”
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215
Increasing temperature decreases oxygen concentration and decreasing oxygen content decreases neuronal excitability.
Published 2012“…Increasing temperature can dramatically decrease oxygen levels. B. Response of layer 2/3 pyramidal cells (n = 5) to the intracellular injection of a depolarizing current pulse (200 pA, 500 ms) at different temperatures (same experiments as in A). …”
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