Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis-0 by Mrigank Srivastava (94935)

“…Ned in lysates of alveolar macrophages and lung parenchymal tissue of mock-treated cath K tg mice as compared to mock-treated wild-type mice (A). In addition, cathepsin K protein was determined in lysates of alveolar macrophages (B), freshly isolated type II alveolar epithelial cells (C), lung parenchymal tissue (D), and concentrated BAL fluid supernatant (E) of mock-treated cath K transgenic and wild-type mice by western blot analysis. …”

Perturbing the ORF57-REF/Aly interaction with point mutations decreases cytoplasmic accumulation of viral mRNA. by Richard B. Tunnicliffe (233562)

“…Point mutations of ORF57 residues implicated in direct interaction with REF, and reducing its binding, all caused significant decrease in cytoplasmic accumulation of viral mRNA.…”

Five exemplary spectrograms showing USV emission (rewarded behavior) followed by the release of a food reward. by Agnieszka D. Wardak (17941139)

Data from '<b>Warm and cool temperatures decrease early-life telomere length in wild pied flycatchers</b>' by Antoine Stier (3596369)

ChAT knock-down using an antisense oligodeoxynucleotide (AS-ODN) against ChAT, and decreased expression of ChAT in the DRG and spinal cord by Misaki Matsumoto (52354)

LC-IMS-CID-MS CKO vs K5Cre results. by Kevin J. Mills (9270966)

“…<div><p>CCAAT/enhancer binding protein- (C/EBP) is a basic leucine zipper transcription factor that is abundantly expressed in epidermal keratinocytes of skin. …”

Meta data to S5 Fig. by Xiaowen Jiang (8291814)

“…Using the zebrafish pectoral fin bud as a model for early vertebrate fin/limb development, we found that K⁺ channels also scale this anatomical structure, and we determined how one K⁺-leak channel, Kcnk5b, integrates into its developmental program. …”

Meta data to Fig 5. by Xiaowen Jiang (8291814)

“…Using the zebrafish pectoral fin bud as a model for early vertebrate fin/limb development, we found that K⁺ channels also scale this anatomical structure, and we determined how one K⁺-leak channel, Kcnk5b, integrates into its developmental program. …”

Taste bud cell populations are decreased after <i>Sox2</i> deletion in epithelial stem/progenitor cells. by Makoto Ohmoto (3065106)

Adaptation to cool temperature decreases basal and stimulated lipolysis and increases <i>de novo</i> lipogenesis and TAG synthesis. by Hiroyuki Mori (512656)

“…ACC, acetyl-CoA carboxylase; ATGL, adipose triglyceride lipase; GSEA, gene set enrichment analysis; FASN, fatty acid synthase; HSL, hormone-sensitive lipase; NEFA, nonesterified fatty acid; PL, phospholipid; TAG, triacylglycerol; TOFA, 5-(tetradecyloxy)-2-furoic acid.…”

nsP4-C483Y or Q192L mutations decrease sensitivity to 4′-FlU. by Peiqi Yin (6533747)

The phosphorylation of sorting nexin 5 at serine 226 regulates retrograde transport and macropinocytosis by Nao Itai (5954666)

Subjects:

Table 1_Multi-generational adaptation to Solanum nigrum increases reproduction and decreases microbial diversity of Aphis gossypii.docx by Peng Wang (34436)

“…Upon retransferring T1, T5, and the tenth generation of A. gossypii (T10) were retransferred to G. hirsutum (designated as T1-M, T5-M, and T10-M, respectively), the T5-M showed superior r, λ, and fecundity compared to both T1-M and T10-M. 16S rRNA sequencing and qPCR analyses indicated a significant decrease in the diversity of the symbiotic bacterial community in both T5 and T10. …”

Lipid Droplet-Binding Protein TIP47 Regulates Hepatitis C Virus RNA Replication through Interaction with the Viral NS5A Protein by Dorothee A. Vogt (247917)

“…A single point mutation (W9A) in NS5A that disrupts the interaction with TIP47 but preserves proper subcellular localization severely decreased HCV RNA replication. …”

Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis-1 by Mrigank Srivastava (94935)

Statistically significant correspondence between human psoriasis and mouse psoriasiform phenotypes: Proportion of psoriasiform-increased to psoriasiform-decreased transcripts. by William R. Swindell (175427)

“…<p>Genes significantly increased or decreased in human psoriasis were identified and the expression of orthologous genes was studied in the K5-Tie2 phenotype (A and B), the IMQ phenotype (C and D), the K14-AREG phenotype on ear skin (E and F), the K14-AREG phenotype on tail skin (G and H), the K5-Stat3C phenotype (I and J), and the K5-TGFβ1 phenotype (K and L). …”

Prion Protein Is Decreased in Alzheimer's Brain and Inversely Correlates with BACE1 Activity, Amyloid-β Levels and Braak Stage by Isobel J. Whitehouse (331843)

“…Contactin 5 (CNTN5) has also been implicated in the development of AD by a genome-wide association study. …”

<i>Myotis rufoniger</i> genome sequence and analyses: <i>M</i>. <i>rufoniger’s</i> genomic feature and the decreasing effective population size of <i>Myotis</i> bats by Youngjune Bhak (3511349)

“…<div><p><i>Myotis rufoniger</i> is a vesper bat in the genus <i>Myotis</i>. Here we report the whole genome sequence and analyses of the <i>M</i>. …”

Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis-4 by Mrigank Srivastava (94935)

Conduction slowing at branching points. by Tanmay A. Gokhale (3687244)

“…<p>(a) As the wavefront travels from right to left (direction of arrow) along the principal axis of conduction (obstacle-to-strand ratio: 5), activation isochrones reveal significant slowing at each branching point (top and bottom panels). …”