Shortening of mTL anticipates accumulation of DDR markers, decrease in cell proliferation and increase in apoptotis with age. by Madalena C. Carneiro (102302)

“…All tissues show a significant increase in cells bearing five or more γH2AX foci by 12 months of age in <i>tert</i>^-/- zebrafish (panels b, d) and by 36 months in WT zebrafish (panels a, c and e). …”

Zileuton, 5-Lipoxygenase Inhibitor, Acts as a Chemopreventive Agent in Intestinal Polyposis, by Modulating Polyp and Systemic Inflammation by Elias Gounaris (52393)

“…Here we report that Zileuton, a specific 5-LO inhibitor, can prevent polyp formation by efficiently reducing the tumor-associated and systemic inflammation in APC^Δ468 mice.…”

The decrease of similarity between the displacement of the center of pressure (COP) and the gaze point inhibited the displacement of the COP. by Hikaru Nakahara (13955347)

HPLC replicates of DAM-1 as standard and comparison view of DAM-1, <i>E</i>.<i>coli</i> + DAM-1 and solvent blank. by Manoj Limbraj Yellurkar (11467219)

An autophagy-inducing compound ML246 reduces amyloid load in an autophagy-dependent manner in vitro and in vivo. by Altea Rocchi (3278457)

<i>Becn1</i>^FA/FA mutation ameliorates cerebral Aβ accumulation, memory deficits and mortality of Alzheimer’s mouse models. by Altea Rocchi (3278457)

Effect of ex vivo treatment with rhTGFβ1 or a TGFβ1 inhibitor on monocyte responses to rgE stimulation. Monocytes and NK cells purified from PBMC collected from 10 RZV recipients (demographics in S4 Table) before vaccination (D0) and 90 days post-vaccination (D90) were combined ex vivo and stimulated with VZV-rgE.... by Michael J. Johnson (5818168)

“…<p>Effect of ex vivo treatment with rhTGFβ1 or a TGFβ1 inhibitor on monocyte responses to rgE stimulation. Monocytes and NK cells purified from PBMC collected from 10 RZV recipients (demographics in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1013759#ppat.1013759.s004" target="_blank">S4 Table</a>) before vaccination (D0) and 90 days post-vaccination (D90) were combined ex vivo and stimulated with VZV-rgE. …”

Total number of hippocampal microRNAs that are increased or decreased after SE at each time point. by Rashmi M. Risbud (290321)

Supplementary Material for: TNFAIP2 Inhibits Early TNFa-Induced NF-κB Signaling and Decreases Survival in Septic Shock Patients by Thair S.A. (4152325)

<i>Becn1</i>^F121A leads to autophagy hyperactivation in vivo. by Altea Rocchi (3278457)

Rac1 activity rapidly decreases upon cell-cell adhesion in 3-D cell aggregates. by Khameeka N. Kitt (227731)

“…High levels of active Rac1 at 0 minutes rapidly decreased (∼66%) within 5 minutes of cell-cell adhesion, and declined to a baseline level by 30 minutes (A). …”

Water protection after tympanostomy (Shepard) tubes does not decrease otorrhea incidence - retrospective cohort study by João Subtil (5629802)

Down-regulation of Bim in EBV-positive cells is not due to proteosomal degradation or decreased mRNA stability. by Kostas Paschos (262658)

Waning of BCG-induced protection against <i>Mtb</i> coincides with decreased T-cell functional capacity. by Subhadra Nandakumar (212501)

Temporal profiles of the key BO-NN features. by Julia Berezutskaya (9080269)

“…Right plot show the gradual decrease in the TM tuning for the features highlighted in <b>c</b> as well as the gradual increase in the temporal response profile (i.e. optimal shifts for the prediction of the key BO-NN features using Praat features shown in <b>a</b>). …”

AMPK activators reverse the decreased expression of GR induced by DEX in cultured prefrontal cortical astrocytes. by Shi-Ying Yuan (2937669)

“…<p>(A) Representative western blot images (upper) and summarized data (lower) showing the effects of AICAR (n = 5 for each group) (A), ASP (n = 4 for each group) (B), and MET (n = 7 for each group) (C) on DEX-induced decreases of GR and pAMPK in cultured astrocytes. …”

Exposure to glucocorticoids decreases the levels of pAMPK and GR in cultured rat prefrontal cortical astrocytes. by Shi-Ying Yuan (2937669)

Decreased CD39 protein expression by islet resident macrophages heralds T1D in NOD mice. by Thomas B. Thornley (2550766)

Decreased expression of SMAD1/5/8 and VEFG in the Botox injected side MCC and subchondral bone. by Eliane H. Dutra (3207312)

Surveillance of HIV Transmitted Drug Resistance in Latin America and the Caribbean: A Systematic Review and Meta-Analysis by Santiago Avila-Rios (3160959)

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