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STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS
Published 2024“…This study investigates the impact of five pathogenic CBS missense mutations [c.1006C>T (p.R336C), c.689T>A (p.L230Q), 215A>T (p.K72I), c.707C>A (p.T236N), and c.457G>A (p.G153R)] identified in homocystinuria patients and appeared to be resistant to pyridoxine treatment on the biochemical and biophysical properties of CBS protein. …”
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623
Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics
Published 2018“…In contrast, in the presence of Ca2+, there was a significant decrease in the stability of the five proteins following the order CaMWT> CaMN98I > CaMD132E > CaMQ136P > CaMD134H. …”
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Impact of Genetic Polymorphisms on Phenytoin Pharmacokinetics and Clinical Outcomes in the Middle East and North Africa Region
Published 2017“…Study quality was assessed using a National Institutes of Health assessment tool. …”
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628
The Influence of Qatari Dust on the Element Composition of Marine Plankton
Published 2021“…The biogenic concentrations of trace metals were determined by correcting the bulk analyses for the lithogenic contribution using aluminum content of Qatari dust as a lithogenic tracer. The relative trace metal composition of plankton from EEZ of Qatar is Fe > Zn ≈ Cu > V ≈ Ni ≈ Cr ≈ As ≈ Mo > Cd ≈ Co. …”
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629
The influence of aeration scheme and aeration rate on the permeate flux for wastewater treatment using membrane bioreactors: Experimental and artificial neural network modeling
Published 2021“…Furthermore, a continuous and pulsed aeration scheme (5 min on and 5 min off) was tested. …”
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630
Flight Scheduling in the Airspace
Published 2016“…The mathematical model has been solved using CPLEX 12.6 and the scatter search has been coded using C language under Microsoft Visual Studio v12 environment. The tests were conducted under a Windows 7 machine with an Intel Core i7 and 8 GB of RAM. …”
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631
INVESTIGATION OF SPATIOTEMPORAL VARIABILITY AND CONTAMINATION OF PLASTIC MARINE DEBRIS IN QATAR’S COASTAL WATERS
Published 2015“…There has been a tremendous proliferation in plastic production in the last five decades due to its low cost and versatile applications. …”
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632
Microstructure and compressive behavior of Al-Y2O3 nanocomposites prepared by microwave-assisted mechanical alloying
Published 2019“…The Al–1.5 vol. % Y2O3 nanocomposite exhibited the best ultimate compressive strength and yielded a strength of 359 ± 7 and 111 ± 5 MPa, respectively. …”
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633
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Enhancing thermal and mechanical response of aluminum using nanolength scale TiC ceramic reinforcement
Published 2018“…the present work, nano-sized titanium carbide (0.5, 1.0 and 1.5 vol%) reinforced aluminum (Al) metal matrix composites were synthesized by powder metallurgy incorporating microwave sintering and hot extrusion. …”
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636
Carbon Emissions Policies and its Impact on the Design of Supply Chains
Published 2016“…This conclusion is also proved by the further investigation when the total cost and emission are observed under decreasing cap. A further investigation reveals the transportation mode doesn't change when the carbon price increase from 9 to 234. …”
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637
Enhancing compressive, tensile, thermal and damping response of pure Al using BN nanoparticles
Published 2018“…The addition of BN nanoparticulates enhanced the damping characteristics of pure Al with Al-1.5 vol.% BN nanocomposite exhibiting the maximum damping capacity and damping loss rate with a minimum change in elastic modulus. …”
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638
Tribological studies of nanomodified mineral based multi-grade engine oil
Published 2017“…Wear rate for lubrication oil without nanoadditives was also found to be decreased with increase in sliding speed. Experimental results prove that nanoparticles can be used as a multifunctional additive in lubricating oil to enhance its tribological properties.…”
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639
Impact of composition and salinity on swelling and gel strength of poly (acrylamide-co-acrylic acid) preformed particle gel
Published 2023“…On the contrary, PPG5, with the lowest acrylic acid and highest crosslinker content, has a swelling capacity of 239 g/g and more than 17 g/g in distilled and brine 1, respectively. …”
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640
Enhanced performance of nano-sized SiC reinforced Al metal matrix nanocomposites synthesized through microwave sintering and hot extrusion techniques
Published 2017“…In the present study, nano-sized SiC (0, 0.3, 0.5, 1.0 and 1.5 vol%) reinforced aluminum (Al) metal matrix composites were fabricated by microwave sintering and hot extrusion techniques. …”
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