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421
Structural analysis of missense mutations in galactokinase 1 (GALK1) leading to galactosemia type-2.
Published 2018“…Molecular docking analysis revealed a decrease in interaction between the protein and ATP in all the 3 mutations, and molecular dynamic simulations of 50 ns showed a loss of stability and compactness in the mutant proteins. …”
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422
Hypospadias Reconstruction Training: Development of an Ex-Vivo Model for Objective Evaluation of Surgical Skills
Published 2025“…ObjectiveTo objectively evaluate technical skill acquisition in hypospadias repair procedures during surgical training using noninvasive wearable sensor technology. MethodsWe combined subjective video evaluations with objective electromyography (EMG) measurements in a hands-on hypospadias training course. …”
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423
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424
Mixed Solid Municipal Waste-Based Biochar for Soil Fertility and Greenhouse Gas Mitigation
Published 2016“…Municipal solid waste management is one of the major challenges facing Qatar with more than 2.5 million tons of municipal solid waste each year, a very high waste generation rate in a country with small land mass. …”
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425
Pharmacoeconomic evaluation of voriconazole vs. liposomal amphotericin B in empiric treatment of invasive fungal infections in Turkey
Published 2013“…Univariate sensitivity analysis highlighted that increasing the duration of voriconazole by >1.2 days or decreasing LAmB by >1.0 days changes the result. Monte Carlo Simulation resulted in 69.4% of simulations favouring voriconazole per patient treated.Conclusion: There is a strong likelihood that voriconazole is economically more favourable than LAmB in the empiric treatment of IFI in Turkey.…”
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426
Exploring Beyond Numeric Weight Loss: The Metabolic Effects of Semaglutide.
Published 2025“…Also, it enhanced glycemic control, as evidenced by significant reductions in hemoglobin A1C (HbA1c) with the 0.5 mg and 1.0 mg doses. From a baseline range of 8.1–8.7%, 0.5mg dose lowered HbA1c by 1.2–1.5%, while the 1.0 mg dose reduced it by 1.4–1.8%. …”
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427
Modeling the influence of daily temperature and precipitation extreme indices on vegetation dynamics in Katsina State using statistical downscaling model (SDM)
Published 2023“…All the scenarios present increasing minimum and maximum temperatures and decreasing precipitation, except for RCP8.5, which predicted a more adverse trend. …”
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428
STRUCTURAL AND FUNCTIONAL APPROACHES TOWARD ACTIVITY RESTORATION OF NOVEL CYSTATHIONINE BETA-SYNTHASE MUTATIONS
Published 2024“…This study investigates the impact of five pathogenic CBS missense mutations [c.1006C>T (p.R336C), c.689T>A (p.L230Q), 215A>T (p.K72I), c.707C>A (p.T236N), and c.457G>A (p.G153R)] identified in homocystinuria patients and appeared to be resistant to pyridoxine treatment on the biochemical and biophysical properties of CBS protein. …”
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429
Calmodulin Mutations Associated with Congenital Cardiac Disease Display Novel Biophysical and Biochemical Characteristics
Published 2018“…In contrast, in the presence of Ca2+, there was a significant decrease in the stability of the five proteins following the order CaMWT> CaMN98I > CaMD132E > CaMQ136P > CaMD134H. …”
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430
Modeling the influence of daily temperature and precipitation extreme indices on vegetation dynamics in Katsina State using statistical downscaling model (SDM)
Published 2023“…All the scenarios present increasing minimum and maximum temperatures and decreasing precipitation, except for RCP8.5, which predicted a more adverse trend. …”
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431
The Impact of Multiple Autoclave Cycles on the Surface Roughness of Thermally Treated Nickel-Titanium Endodontic Files
Published 2022“…Overall, 60 thermally treated files were sourced (i.e., 20 TN, 20 ETP, and 20 PTG files), and each group was divided into four equal subgroups of five files (n = 5). An unsterilized group was assigned as the pre-autoclaving group (Cycle 0), and the other three groups underwent various autoclave sterilization cycles (Cycles 1, 5, and 10). …”
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432
Flight Scheduling in the Airspace
Published 2016“…In this study, we developed a scatter search (SS) to deal with larger instances. …”
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433
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434
Effect of Magnetic Baffles and Magnetic Nanofluid on Thermo-Hydraulic Characteristics of Dimple Mini Channel for Thermal Energy Applications
Published 2022“…The increment changed to 1.82%, 8.16%, and 22.31% for a pitch = 5 mm and 1.01%, 5.96%, and 21.38% for a pitch = 2.5 mm. …”
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435
The Effects of Class IV Hemorrhagic Hypotensive Shock and Its Resuscitation with Fluids and Adjuvant Vasopressors or Cellular Energy Replenishment on the Splanchnic Microcirculatio...
Published 2016“…The transected organ was returned to the abdominal cavity for free arterial and venous bleeding until class IV hemorrhage is achieved [defined by persistent mean arterial pressure, MAP < 40 mmHg, and a shock index (ratio of heart rate and systolic arterial pressure), SI ≥ 5 for successive 10 minutes during the period of active uncontrolled bleeding]. …”
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436
Effects of financial turmoil on financial integration and risk premia in emerging markets
Published 2016“…The aim of this article is to analyze how financial crises affect the dynamics of international financial integration and of the risk premia in emerging markets. Accordingly, we estimate a variant of the International Asset Pricing Model developed by Carrieri et al. (2007), allowing for time-varying stock market integration, in which we include the foreign currency risk. …”
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437
Experimental study on effective placement of PCM packets in cooling vest to improve performance in warm environment
Published 2017“…The used PCM melting temperature is 28 °C with a coverage area of 642 cm2 and total weight of the vest of 1.19 kg including 8 PCM packets (87.5 grams each). …”
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The Effect of Hyperoxia on Central and Peripheral Factors of Arm Flexor Muscles Fatigue Following Maximal Ergometer Rowing in Men
Published 2022“…Methods: In 11 competitive male rowers (age, 30 ± 4 years), we measured near-infrared spectroscopy determined frontal lobe oxygenation (ScO2) and transcranial Doppler ultrasound determined middle cerebral artery mean flow velocity (MCA Vmean) combined with maximal voluntary force (MVC), peak resting twitch force (Ptw) and cortical voluntary activation (VATMS) of the elbow flexor muscles using electrical motor point and magnetic motor cortex stimulation, respectively, before, during, and immediately after 2,000 m all-out effort on rowing ergometer with normoxia and hyperoxia (30% O2). …”
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440
Caffeine use or napping to enhance repeated sprint performance after partial sleep deprivation: Why not both?
Published 2021“…Purpose: To compare the effect of a 20-minute nap opportunity (N20), a moderate dose of caffeine (CAF; 5 mg·kg-1), or a moderate dose of caffeine before N20 (CAF+N) as possible countermeasures to the decreased performance and the partial sleep deprivation-induced muscle damage. …”
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