Image_4_Tocilizumab (TCZ) Decreases Angiogenesis in Rheumatoid Arthritis Through Its Regulatory Effect on miR-146a-5p and EMMPRIN/CD147.jpeg by Devy Zisman (11838428)

“…Transfection of HT1080 cells with the miR-146a-5p mimic, decreased the accumulation of EMMPRIN, VEGF and MMP-9. …”

Image_2_Tocilizumab (TCZ) Decreases Angiogenesis in Rheumatoid Arthritis Through Its Regulatory Effect on miR-146a-5p and EMMPRIN/CD147.jpeg by Devy Zisman (11838428)

“…Transfection of HT1080 cells with the miR-146a-5p mimic, decreased the accumulation of EMMPRIN, VEGF and MMP-9. …”

Image_1_Tocilizumab (TCZ) Decreases Angiogenesis in Rheumatoid Arthritis Through Its Regulatory Effect on miR-146a-5p and EMMPRIN/CD147.jpeg by Devy Zisman (11838428)

“…Transfection of HT1080 cells with the miR-146a-5p mimic, decreased the accumulation of EMMPRIN, VEGF and MMP-9. …”

Image5_The G protein biased serotonin 5-HT2A receptor agonist lisuride exerts anti-depressant drug-like activities in mice.JPEG by Vladimir M. Pogorelov (133492)

“…Despite these benefits, the hallucinogenic actions of these drugs at the serotonin 2A receptor (5-HT2AR) limit their clinical use in diverse settings. …”

U87MG glioma cells transduced with gal-3 shRNA demonstrate decreased tumor size and growth. by Rafael Yamashita Ikemori (698128)

“…The inoculation of U87MG gal-3 shRNA cells in the flank of nuce mice (n = 5) demonstrated a decrease in tumor size and growth compared to the U87MG scramble shRNA (n = 6). …”

The mitochondrial ROS-counteracting protein PRDX3 is decreased in NRF2i-DMA cells. by Bo-hyun Choi (630240)

Ablation of Tph1 gene in dams decreased circulating serotonin and calcium on day 1 and 10 of lactation. by Jimena Laporta (383836)

Hormone therapy decreased β-amyloid load and improved cognitive performance in early middle-aged mice. by Amy Christensen (4062937)

Structurally distinct inhibitors of Chk1 decrease Chk1 nuclear fluorescence following heating in a low well volume. by Andrew J. Massey (239469)

Replacing i3 of Rs1 with that of 5-HT_1A results in a receptor, Rs1-i3-5-HT_1A, with weak G_isignaling. by Wei Chun Chang (43479)

“…<p>(A) Rs1-i3-5-HT_1A chimera decreased cAMP accumulation. …”

<i>patDp</i>/+ mice have decreased tissue 5-HT and increased tissue DA levels during postnatal development. by Kota Tamada (235174)

Video_5_Contribution of 5-HT2 Receptors to the Control of the Spinal Locomotor System in Intact Rats.WMV by Henryk Majczyński (830716)

“…Little is known about the role of 5-HT receptors in the control of voluntary locomotion, so we administered inverse agonists of 5-HT₂ (Cyproheptadine; Cypr), 5-HT_2A neutral antagonist (Volinanserin; Volin), 5-HT_2C neutral antagonist (SB 242084), and 5-HT_2B/2C inverse agonist (SB 206553) receptors intrathecally in intact rats and monitored their effects on unrestrained locomotion. …”

Panc1 cells were transfected with siHOTTIP, siHOTAIR or siMALAT-1, and changes in gene expression were determined using human HT-12 V4 expression bead chip arrays. by Yating Cheng (523668)

Upregulation of 5-Hydroxytryptamine Receptor Signaling in Coronary Arteries after Organ Culture by Chun-Yu Deng (293972)

“…<div><p>Background</p><p>5-Hydroxytryptamine (5-HT) is a powerful constrictor of coronary arteries and is considered to be involved in the pathophysiological mechanisms of coronary-artery spasm. …”

5-HT₇Dro modulates courtship and mating. by Jaime Becnel (218896)

Inhibitor of endogenous 5HT synthesis prevents facilitation by oxytocin of FL. by Francesco Dose (540963)

“…On the following day, in both preparations, a stable FL is recorded in the presence of NMDA (5 μM) plus 5HT (10 μM; A, B, left). …”

5-HT_2C receptor editing in the hippocampus. by Harriët Schellekens (328795)

“…A) Decreased expression of the unedited 5-HT_2C-INI isoform in hippocampus of <i>ob/ob</i> mice, but not statistically significant. …”

Crosslinking decreases the alignment of fibers associated with individual cells migrating out of spheroids. by Michael Pamonag (12295175)

IFNγ enhances the Ser/5-HT-promoted <i>Trypanosoma cruzi</i> uptake by the human U-87 MG astroglioma cells. by Glaucia Vilar-Pereira (686134)

Fx treatment abrogates the Ser/5-HT-promoted <i>Trypanosoma cruzi</i> infection of human U-87 MG astroglioma cells. by Glaucia Vilar-Pereira (686134)