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a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
a fold » 5 fold (Expand Search), _ fold (Expand Search), 2 fold (Expand Search)
fold decrease » fold increase (Expand Search), fold increased (Expand Search)
026 decrease » _ decrease (Expand Search)
nn decrease » _ decrease (Expand Search), mean decrease (Expand Search), gy decreased (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
a fold » 5 fold (Expand Search), _ fold (Expand Search), 2 fold (Expand Search)
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Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model
Published 2024“…Mouse PK indicated that <b>6</b> is cleared 10-fold more rapidly than a first-generation GRM payload, resulting in 10-fold lower exposure and 3-fold decrease in Cmax. …”
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Anti-TNF Thioester Glucocorticoid Antibody–Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model
Published 2024“…Mouse PK indicated that <b>6</b> is cleared 10-fold more rapidly than a first-generation GRM payload, resulting in 10-fold lower exposure and 3-fold decrease in Cmax. …”
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Decreased hyper-resection in a NuA4 acetylation defective mutant in G1 and defect in DNA break repair by SSA.
Published 2021“…(F) The <i>esa1-ts</i> mutation leads to a decrease of DSB repair by resection-based single-strand annealing. …”
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