New Dual P‑Glycoprotein (P-gp) and Human Carbonic Anhydrase XII (hCA XII) Inhibitors as Multidrug Resistance (MDR) Reversers in Cancer Cells by Laura Braconi (8679744)

“…Indeed, hCA XII modulates the efflux activity of P-gp and the inhibition of hCA XII reduces the intracellular pH, thereby decreasing the ATPase activity of P-gp. All compounds showed inhibitory activities on P-gp and hCA XII proteins taken individually, and many of them displayed a synergistic effect in HT29/DOX and A549/DOX cells that overexpress both P-gp and hCA XII, being more potent than in K562/DOX cells overexpressing only P-gp. …”

KB-8-5 cells were transduced with IVP-scrambled (S) or IVP-antigene PNA (P) and the P-gp-mediated efflux capacity was measured through the efflux of the fluorescent dye Rhodamine 1... by Benjamin Macadangdang (226890)

Generation of Arid3b conditional knockout system. by Jeffrey L. Kurkewich (3044211)

A small proportion of Talin molecules transmit forces at developing muscle attachments in vivo by Sandra B. Lemke (6519788)

“…Concomitantly, the Talin concentration at attachment sites increases 5-fold as quantified by fluorescence correlation spectroscopy (FCS), suggesting that only a small proportion of Talin molecules are mechanically engaged at any given time. …”

MXene-Reinforced Antifreezing Conductive Eutectogel with Enhanced Sensing Sensitivity for Low-Temperature Wearable Sensors by Aobo Ren (9651579)

“…However, the water in hydrogels is prone to freezing at low temperatures, decreasing flexibility and sensing performance. In this work, a dual-network eutectogel composed of poly­(vinyl alcohol) and poly­(acrylic acid) is prepared by using deep eutectic solvent (DES) and MXene as the antifreezing medium and conductive component, respectively. …”

The relationship between ecosystem multifunctionality and bacterial Chao1 estimated richness. by Melissa S. Shinfuku (19942206)

Ecosystem multifunctionality across warming treatment and season. by Melissa S. Shinfuku (19942206)

The COVID pandemic in Chile: Own construction using administrative data from the Ministry of Health. by Raimundo Atal (18272064)

Presentation_1_Decreased miR-4512 Levels in Monocytes and Macrophages of Individuals With Systemic Lupus Erythematosus Contribute to Innate Immune Activation and Neutrsophil NETosi... by Binbin Yang (2259313)

“…We aimed to elucidate the mechanisms and therapeutic potential of microRNAs (miRNAs) in SLE in a Tibetan population.</p>Methods<p>Peripheral blood mononuclear cells from SLE patients (n = 5) and healthy controls (n = 5) were used for miRNA–mRNA co-sequencing to detect miRNAs related to immune abnormalities associated with SLE. …”

Image_2_Decreased miR-4512 Levels in Monocytes and Macrophages of Individuals With Systemic Lupus Erythematosus Contribute to Innate Immune Activation and Neutrsophil NETosis by Ta... by Binbin Yang (2259313)

“…We aimed to elucidate the mechanisms and therapeutic potential of microRNAs (miRNAs) in SLE in a Tibetan population.</p>Methods<p>Peripheral blood mononuclear cells from SLE patients (n = 5) and healthy controls (n = 5) were used for miRNA–mRNA co-sequencing to detect miRNAs related to immune abnormalities associated with SLE. …”

Image_3_Decreased miR-4512 Levels in Monocytes and Macrophages of Individuals With Systemic Lupus Erythematosus Contribute to Innate Immune Activation and Neutrsophil NETosis by Ta... by Binbin Yang (2259313)

“…We aimed to elucidate the mechanisms and therapeutic potential of microRNAs (miRNAs) in SLE in a Tibetan population.</p>Methods<p>Peripheral blood mononuclear cells from SLE patients (n = 5) and healthy controls (n = 5) were used for miRNA–mRNA co-sequencing to detect miRNAs related to immune abnormalities associated with SLE. …”

Table_2_Decreased miR-4512 Levels in Monocytes and Macrophages of Individuals With Systemic Lupus Erythematosus Contribute to Innate Immune Activation and Neutrsophil NETosis by Ta... by Binbin Yang (2259313)

“…We aimed to elucidate the mechanisms and therapeutic potential of microRNAs (miRNAs) in SLE in a Tibetan population.</p>Methods<p>Peripheral blood mononuclear cells from SLE patients (n = 5) and healthy controls (n = 5) were used for miRNA–mRNA co-sequencing to detect miRNAs related to immune abnormalities associated with SLE. …”

Image_1_Decreased miR-4512 Levels in Monocytes and Macrophages of Individuals With Systemic Lupus Erythematosus Contribute to Innate Immune Activation and Neutrsophil NETosis by Ta... by Binbin Yang (2259313)

“…We aimed to elucidate the mechanisms and therapeutic potential of microRNAs (miRNAs) in SLE in a Tibetan population.</p>Methods<p>Peripheral blood mononuclear cells from SLE patients (n = 5) and healthy controls (n = 5) were used for miRNA–mRNA co-sequencing to detect miRNAs related to immune abnormalities associated with SLE. …”

Table_1_Decreased miR-4512 Levels in Monocytes and Macrophages of Individuals With Systemic Lupus Erythematosus Contribute to Innate Immune Activation and Neutrsophil NETosis by Ta... by Binbin Yang (2259313)

“…We aimed to elucidate the mechanisms and therapeutic potential of microRNAs (miRNAs) in SLE in a Tibetan population.</p>Methods<p>Peripheral blood mononuclear cells from SLE patients (n = 5) and healthy controls (n = 5) were used for miRNA–mRNA co-sequencing to detect miRNAs related to immune abnormalities associated with SLE. …”

Image_4_Decreased miR-4512 Levels in Monocytes and Macrophages of Individuals With Systemic Lupus Erythematosus Contribute to Innate Immune Activation and Neutrsophil NETosis by Ta... by Binbin Yang (2259313)

“…We aimed to elucidate the mechanisms and therapeutic potential of microRNAs (miRNAs) in SLE in a Tibetan population.</p>Methods<p>Peripheral blood mononuclear cells from SLE patients (n = 5) and healthy controls (n = 5) were used for miRNA–mRNA co-sequencing to detect miRNAs related to immune abnormalities associated with SLE. …”

Main results including COVID-19 deaths. by Raimundo Atal (18272064)

<i>De Novo</i> B cell production is critically impaired in Arid3b null mice. by Jeffrey L. Kurkewich (3044211)

Erythroid and myeloid progenitor lineages are unperturbed in <i>Arid3b</i>^<i>-/-</i> mice. by Jeffrey L. Kurkewich (3044211)

Supplementary Material for: IFNγ-Inducible Chemokines Decrease upon Selenomethionine Supplementation in Women with Euthyroid Autoimmune Thyroiditis: Comparison between Two Doses of... by Pilli T. (4156702)

Analysis of T cell population in thymus of <i>Arid3b</i>^<i>-/-</i> mice. by Jeffrey L. Kurkewich (3044211)