Impact of Replacing Smear Microscopy with Xpert MTB/RIF for Diagnosing Tuberculosis in Brazil: A Stepped-Wedge Cluster-Randomized Trial by Betina Durovni (375250)

“…However, the overall notification rate did not increase (15%, 95% CI = −6%, 37%), and we observed no change in the notification rate for those without a test result (−3%, 95% CI = −37%, 30%). Median time to treatment decreased from 11.4 d (interquartile range [IQR] = 8.5–14.5) to 8.1 d (IQR = 5.4–9.3) (<i>p</i> = 0.04), although not among confirmed cases (median 7.5 [IQR = 4.9–10.0] versus 7.3 [IQR = 3.4–9.0], <i>p</i> = 0.51). …”

Depletion of Atg5 inhibits IDN5706-induced autophagy, but not EDEM1 degradation. by Viviana A. Cavieres (500139)

Accumulated immature APP in response to IDN5706 is degraded by Atg5-dependent autophagy. by Viviana A. Cavieres (500139)

Decreased IL-17A production by DGKζ deficient <i>i</i>NKT cells following α-GalCer stimulation in vitro. by Jinhong Wu (424170)

Vaccine-Induced IgG Antibodies to V1V2 Regions of Multiple HIV-1 Subtypes Correlate with Decreased Risk of HIV-1 Infection by Susan Zolla-Pazner (156004)

The complex III turnover is decreased in Myc-ON mice (n = 5) compared with the Myc-OFF (n = 5) or single transgenic mice (Single Tg) (n = 4). by Hyoung-gon Lee (73934)

Video5_Decreased Interfacial Dynamics Caused by the N501Y Mutation in the SARS-CoV-2 S1 Spike:ACE2 Complex.MOV by Wesam S. Ahmed (10170053)

Loss of <i>Ubr5</i> function resulted in decreased expression of <i>Ptch1</i> and <i>Gli1</i> at E13.5. by Elaine Kinsella (2833466)

Rictor deletion leads to a decrease in B cells in the PB and spleen. by Yingchi Zhang (607489)

Embryonic caffeine exposure leads to a decrease in global DNA methylation. by Daniela L. Buscariollo (140729)

“…<p>DNA was isolated from adult left ventricles of mice treated <i>in utero</i> with caffeine. (A) The percentage of 5-methylcytosine decreased in caff+/+ hearts compared to veh+/+ controls, but no change in global DNA methylation levels was observed in caff+/− hearts compared to veh+/− hearts. …”

Mitochondrial protein acetylation correlates with a decrease in sirtuin 3 levels. by Mercedes García-Roche (6459200)

Overexpression of tau inhibited whole-cell currents through Kv channels. by Xiantao Li (683919)

“…<p>(A) The outward Kv currents were evoked by stepped up to +60 mV for 500 ms at a holding potential of -80 mV in N2A cells. …”

Effect of SNX5 S226 phosphorylation on macropinocytosis. by Nao Itai (5954666)

Subjects:

Changes in the localization of SNX5 S226 mutants. by Nao Itai (5954666)

Subjects:

A simple stochastic step model explains Reactive Oxygen Species production in cell populations undergoing senescence and in immortal cells. by Conor Lawless (183686)

“…<p>A) Hypothesis: Schematic representation of a step increase in phenotype for 100 cells. …”

IL-15 decreased early apoptosis of α-GalCer-treated iNKT cells in SLE patients. by Chien-Ya Hsu (11868746)

Subjects:

Decreased expression of TCA cycle and ETC enzymes in kidneys from rats administered Tl. by Sho Sugahara (11895828)

DHT increases whereas orchidectomy decreases the seminal vesicle weight in wild-type and SOD1-G93A mice. by Young-Eun Yoo (323357)

“…Conversely, orchidectomy decreased the seminal vesicle weight in both WT mice (28.4±13 mg, <i>p</i><0.0001) and SOD1 mice (20.8±3.5 mg, <i>p</i><0.0001) compared with control WT and SOD1 mice, respectively. …”

Glucocorticoid receptor knockdown is associated with a decrease in nuclear Nrf2. by Elena Obrador (559979)

Knock-down of <i>PYCR1</i> decreases growth of CRC cell lines. by Saif Sattar Alaqbi (12055053)