Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... حسب Shuai Wang (109515)

الموضوعات:

Discovery of the Triazolo[1,5‑<i>a</i>]Pyrimidine-Based Derivative WS-898 as a Highly Efficacious and Orally Bioavailable ABCB1 Inhibitor Capable of Overcoming Multidrug Resistance... حسب Shuai Wang (109515)

الموضوعات:

Leg and wing <i>IR52a</i>^<i>+</i> neurons form functional connections with neurons in the SEZ. حسب Zhe He (508742)

Oxytocin decreases postsynaptic CeA spontaneous GABAergic transmission and blocks presynaptic alcohol effects. حسب Brendan J. Tunstall (6593357)

"…<p>(A, Top) Representative GABA_A-mediated sIPSCs of CeA neurons from nondependent and dependent rats prior to (baseline) and during application of oxytocin (500 nM). …"

UPLC-DAD profile (270 nm) of phytocannabinoids in the extracts separated in C18 column. حسب Bruno Musetti (9527085)

Dynamin inhibitors decrease the viability of acute leukemia cells. حسب Christopher von Beek (11401835)

Germ cell size decreases before corpse formation. حسب Tea Kohlbrenner (19476160)

MigC interacts with and decreases the activity of MurD. حسب Jeanette M. Critchlow (21553796)

HFD induces LDs and decreases ER and mitochondria in nephrocytes. حسب Aleksandra Lubojemska (10746241)

"…(<b>E</b>) Low and high magnification views of pericardial nephrocytes (dotted outlines) from STD and HFD larvae, showing that HFD decreases mitochondria (marked with anti-ATP5A) and ER (marked with anti-KDEL) but increases LDs (marked with LipidTOX). …"

The combination of LPS and PFC caused faster clot initiation and decreased clot strength. حسب Heather F. Pidcoke (9023789)

"…By RM ANOVA, the time effects were obscured by interaction with group: SAL-SAL, p = NS; LPS-SAL, MA increases with time; T0 v T72 and T96, p≤0.05; SAL-PFC: MA drops @ T96, p≤0.05; LPS-PFC: T0 v all others, p≤0.05 with a recovery at T96, (p≤0.05 compared to T72); SAL-PFC: no significant change, p = NS. …"

Propagation of an action potential through ephaptic coupling is achieved for a decreased extracellular conductivity. حسب Karoline Horgmo Jæger (6785450)

An enhanced clot growth rate before in vitro fertilization decreases the probability of pregnancy حسب A. N. Balandina (6729380)

eIF5a is up-regulated in unruptured AAAs and decreased in ruptured AAAs. حسب Dong Ma (584680)

الموضوعات:

Etesevimab in combination with JS026 neutralizing SARS-CoV-2 and its variants حسب Fengze Wang (10452968)

"…A cocktail of etesevimab and JS026 increased neutralizing efficacy against both wild-type SARS-CoV-2 and the recent emergence of Alpha, Beta, Gamma, and Delta variants. …"

Plasma DEX concentrations in C57BL/6 VD₃ sufficient and deficient mice on a discontinuous DEX regimen. حسب Kavya Annu (11587215)

ABT199 inhibits ALK ^mutant kinase activity and decreases it phosphorylation. حسب Richard Junior Zapata Dongo (17912565)

Synthesis and Biological Evaluation of MEK/mTOR Multifunctional Inhibitors as Novel Anticancer Agents حسب Marcian E. Van Dort (21374093)

الموضوعات:

HAstV-8 (D471S, N512D) spike has decreased or no binding to FcRn compared to wild-type HAstV-8 spike. حسب Catalina Aguilera-Flores (21743843)

Data_Sheet_1_Hepcidin Decreases Rotenone-Induced α-Synuclein Accumulation via Autophagy in SH-SY5Y Cells.PDF حسب Meiqi Li (4169182)

"…We demonstrated that SH-SY5Y cell viability was impaired after rotenone treatment in a dose-dependent manner. α-syn expression and iron content increased under a low concentration rotenone (25 nM for 3 days) treatment in SH-SY5Y cells. …"

A ratio showing a decrease in the volume of the biggest cavity during the last stage of the simulations (elongation). حسب Łukasz Mioduszewski (8967434)