Image_2_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpeg by Mohamed Khass (695111)

“…To investigate the effect of λ5 and/or B cells on bone acquisition over time, we developed a panel of J_H^-/-, λ5^-/-, J_H^-/- λ5^-/-, and wild-type (WT) BALB/c mice and then studied postnatal bone development and aging in these mice at one, six, twelve, and twenty-two months of age. …”

Image_1_Decreased IGF1R attenuates senescence and improves function in pancreatic β-cells.tif by Kanako Iwasaki (16451151)

“…Decreased senescence and improved insulin-secretory function of β-cells were also evident when the βIgf1rKD mice were fed a high-fat diet (HFD; 60% kcal from fat, for 5 weeks).…”

Table_1_Decreased IGF1R attenuates senescence and improves function in pancreatic β-cells.docx by Kanako Iwasaki (16451151)

“…Decreased senescence and improved insulin-secretory function of β-cells were also evident when the βIgf1rKD mice were fed a high-fat diet (HFD; 60% kcal from fat, for 5 weeks).…”

Image_3_Decreased IGF1R attenuates senescence and improves function in pancreatic β-cells.tif by Kanako Iwasaki (16451151)

“…Decreased senescence and improved insulin-secretory function of β-cells were also evident when the βIgf1rKD mice were fed a high-fat diet (HFD; 60% kcal from fat, for 5 weeks).…”

Image_2_Decreased IGF1R attenuates senescence and improves function in pancreatic β-cells.tif by Kanako Iwasaki (16451151)

“…Decreased senescence and improved insulin-secretory function of β-cells were also evident when the βIgf1rKD mice were fed a high-fat diet (HFD; 60% kcal from fat, for 5 weeks).…”

Participants characteristics. by Sakiko Fukui (387048)

“…</p><p>Methods</p><p>Sixty-nine deceased older adults from five special nursing homes were studied over 3.5 years (January 2016 to June 2020). …”

Image_1_IL-1β enhances cell viability and decreases 5-FU sensitivity in novel colon cancer cell lines derived from African American patients.tif by Marzia Spagnardi (9330602)

“…A significant decrease in the response to 5-FU treatment, as well as a significant increase in phosphorylation of IκBα and secretion of IL-8, was seen following IL-1β treatment, in both AA and CA cell lines. …”

Image_2_IL-1β enhances cell viability and decreases 5-FU sensitivity in novel colon cancer cell lines derived from African American patients.tif by Marzia Spagnardi (9330602)

“…A significant decrease in the response to 5-FU treatment, as well as a significant increase in phosphorylation of IκBα and secretion of IL-8, was seen following IL-1β treatment, in both AA and CA cell lines. …”

Data_Sheet_5_Chronic Neurobehavioral Impairments and Decreased Hippocampal Expression of Genes Important for Brain Glucose Utilization in a Mouse Model of Mild TBI.xlsx by Linda M. Huynh (9395591)

“…The expression of the mRNAs encoding PK, and PDH, two critical enzymes in glucose metabolism, was decreased at all-time points only in the hippocampus, but was unchanged in the brainstem, hypothalamus, and cortex in mTBI mice. mTBI mice also exhibited the following behavioral alterations: (1) decreased spatial learning and memory 2, 4, and 6 months after the injury, (2) increased proportion of time spent on open vs. closed arms determined by EPM, and (3) accelerated reduction in motor activity observed at 4 months, two months earlier than observed in the sham group, during the EPM testing. …”

Image_1_Artesunate Alleviates Paclitaxel-Induced Neuropathic Pain in Mice by Decreasing Metabotropic Glutamate Receptor 5 Activity and Neuroinflammation in Primary Sensory Neurons.... by Yize Li (471459)

“…Artesunate normalized paclitaxel-related expression changes in DRG mGluR5, NR1, and GluA2, as well as six paclitaxel related neuroinflammation markers. …”

Root Mean Square Error (RMSE) decreases with number of structures used. by Samuel Coulbourn Flores (11636717)

Evaluation of the Acid Baking Technique to Decrease the Phosphorus Content of the Iron Ore by Leonardo Martins da Silva (7425692)

“…One alternative is to develop pretreatment of the iron ore concentrates producing raw materials with lower phosphorus. …”

Decreased vagal activity and deviation in sympathetic activity precedes development of diabetes by Da Young Lee (8617365)

“…We compared the risk of diabetes until 2017 according to tertiles of heart rate and HRV variables, with tertile 1 serving as the reference group.…”

Does Mean Platelet Volume Decrease in the presence of Coronary Artery Fistula? by Isa Sincer (7234577)

“…In the literature, there is no previous study about the association between hematologic parameters and congenital CAF. For this reason, we aimed to investigate the association of MPV with CAF. …”

Development of Selective and Soluble Mitochondrial Complex 1 Inhibitors Derived from Papaverine for Radiosensitization of Cancer by Ben J. Haines (22458462)

“…Papaverine and some derivatives were previously shown to inhibit mitochondrial complex 1 and decrease oxygen consumption, reversing hypoxia and radiosensitizing model tumors. …”

Development of Selective and Soluble Mitochondrial Complex 1 Inhibitors Derived from Papaverine for Radiosensitization of Cancer by Ben J. Haines (22458462)

“…Papaverine and some derivatives were previously shown to inhibit mitochondrial complex 1 and decrease oxygen consumption, reversing hypoxia and radiosensitizing model tumors. …”

A genome-wide association study implicates that the <i>TTC39C</i> gene is associated with diabetic maculopathy with decreased visual acuity by Weihua Meng (2954112)

“…</p> <p><b>Conclusions</b>: We suggest that the <i>TTC39C</i> gene is associated with diabetic maculopathy with decreased visual acuity. …”

Image_1_TRAPS mutations in Tnfrsf1a decrease the responsiveness to TNFα via reduced cell surface expression of TNFR1.tif by Takahiko Akagi (13138338)

“…Three Tnfrsf1a mutant strains were generated by introducing T79M, G87V, or T90I mutation. …”

Colistin-phage combinations decrease antibiotic resistance in <i>Acinetobacter baumannii</i> via changes in envelope architecture by Xiaoqing Wang (514179)

Increased labor induction and women presenting with decreased or altered fetal movements - a population-based survey by Anna Akselsson (6659081)

“…</p><p>Results</p><p>Labor was induced more often among the 2683 women who had sought care due to decreased or altered fetal movements (RR 1.4, 95% CI 1.3–1.5). …”