Datasheet2_Impact of lockdown on children with type-1 diabetes: returning to the community was associated with a decrease in HbA1c.pdf حسب Benjamin Morat (17677977)

"…No significant difference was observed between medians of HbA1c_mean and HbA1c_after values (8.37% [7.88; 9.32%] vs. 8.50% [7.70; 9.50%], respectively; p = 0.391). …"

Decrease in vRNA in brain during antiretroviral therapy. حسب Sonny R. Elizaldi (9684796)

Normalized pressure pain thresholds (PPTs) (mean ± SEM) at start, middle, end and 5 minutes after a standardized tourniquet test. حسب Jeanette Tour (10790855)

Synthesis and Biological Evaluation of Peripheral 5HT_2B Antagonists for Liver Fibrosis حسب Jihyeon Yoon (8705706)

"…<b>19c</b> markedly reduced fibrotic deposition, with a decrease in fibrosis stage and area in the CCl₄-induced liver fibrosis mouse model. …"

Synthesis and Biological Evaluation of Peripheral 5HT_2B Antagonists for Liver Fibrosis حسب Jihyeon Yoon (8705706)

"…<b>19c</b> markedly reduced fibrotic deposition, with a decrease in fibrosis stage and area in the CCl₄-induced liver fibrosis mouse model. …"

Additional Analysis of visually induced calcium transients in Fig 5. حسب Maureen M. Sampson (9322886)

"…<p>Visually induced calcium transients were recorded in flies expressing L2-split-GAL4>GCaMP6f as in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009003#pgen.1009003.g005" target="_blank">Fig 5</a>. …"

pDNA-PK levels are decreased in absence of cGAS. حسب Elona Gusho (4688170)

cIN accumulate in the ventrolateral cortex of <i>Emx1</i>-cKO mice. حسب Sathish Venkataramanappa (10331993)

Additional Analysis of visually induced calcium transients in Fig 6. حسب Maureen M. Sampson (9322886)

"…<p>Visually induced calcium transients were recorded in 5-HT2B +/- or 5-HT2B -/- flies as described in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009003#pgen.1009003.g006" target="_blank">Fig 6</a>. …"

Decrease in ISV diameter exacerbates the decrease in WSS caused by hematocrit reduction. حسب Swe Soe Maung Ye (12895103)

Serotonin modulates L2 neuron visually induced calcium transient kinetics. حسب Maureen M. Sampson (9322886)

"…Light or dark stimuli (A, middle panel, white and black vertical bars respectively) were flashed at random every 5 s for 6 min. …"

LuxR G37V has decreased DNA-binding activity. حسب Chelsea A. Simpson (9579303)

mGluR5 receptor decreased glycinergic currents. حسب Zi-Yang Zhang (4988555)

"…(<b>E</b>) The inhibitory effect of CHPG on GlyR-IPSCs was not blocked by intracellularly loaded GDP-β-S (62.3 ± 6.4% of baseline at 15–20 min post-CHPG, <i>t</i>[6] = 2.782, <i>p</i> = 0.032), chelerythrine (60.9 ± 11.3% of baseline at 15–20 min post-CHPG, <i>t</i>[6] = 2.705, <i>p</i> = 0.035), or Ro-32-0432 (69.9 ± 3.2% of baseline at 15–20 min post-CHPG, <i>t</i>[5] = 8.495, <i>p</i> < 0.001). (<b>F</b>) Postsynaptic loading of U-0126 or PD98059 prevented CHPG from decreasing glycinergic responses (U-0126, 107.6 ± 10.4% of baseline at 15–20 min post-CHPG, <i>t</i>[8] = 0.997, <i>p</i> = 0.348; PD98059, 93.1 ± 5.0% of baseline at 15–20 min post-CHPG, <i>t</i>[5] = 0.883, <i>p</i> = 0.418). …"

Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor حسب Anat Levit Kaplan (12126567)

"…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …"

Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor حسب Anat Levit Kaplan (12126567)

"…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …"

Ivermectin significantly decreases <i>L</i>. <i>loa</i> mf in BALB/c mice. حسب Rene Bilingwe Ayiseh (6900296)

RhoA gene expression and activity are impacted with increased intracellular 5HT. حسب Celeste M. Sheftel (9557588)

"…<p><b>A.</b><i>RhoA</i> mRNA expression is significantly upregulated with FLX and 5HTP compared to controls and is significantly decreased in FLX + MDC. …"

Design, Synthesis, and Biological Evaluation of New Peripheral 5HT_2A Antagonists for Nonalcoholic Fatty Liver Disease حسب Minhee Kim (1592440)

"…Here, structural modifications of pimavanserin (CNS drug), a 5HT_2A antagonist approved for Parkinson’s disease, led us to synthesize new peripherally acting 5HT_2A antagonists. …"

Decreases in muscle size, muscle force, and TB mass in 3-mo Lmna^HSA-cko mice. حسب Lei Xiong (334812)

Data Sheet 1_Dose-dependent changes in global brain activity and functional connectivity following exposure to psilocybin: a BOLD MRI study in awake rats.pdf حسب Evan Fuini (21224939)