IGF-1 injections significantly attenuate the increase in CD4+CD8+ double positive T cells seen at day 30 after IR. by Jordan A. Gunning (18143970)

IGF-1 injections alone do not alter the immune phenotype at day 30. by Jordan A. Gunning (18143970)

Prb1 overexpression decreased APCs in ESCRT-mutant cells after nitrogen starvation. by Zulin Wu (4451572)

“…Either Prb1 or Snf7 in <i>snf7Δ</i> cells facilitated GFP-Atg8 degradation and prApe1 maturation (bottom), but only Snf7 (not Prb1) facilitated phagophore closure in <i>snf7Δ</i> cells. The red arrows point to these key results. <b>F.</b> The blots shown in panel E were quantified as described in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1010431#pgen.1010431.g006" target="_blank">Fig 6A and 6B</a>. …”

IGF-1 injections significantly attenuate the increase in macrophages and neutrophils observed at day 30 following IR. by Jordan A. Gunning (18143970)

Single color controls for CD3, CD4, CD8, and CD49b antibodies. by Jordan A. Gunning (18143970)

Single color controls for F4/80, Ly-6G, CD11b, and CD45. by Jordan A. Gunning (18143970)

Flow cytometry plots and gating strategy for lymphocytes in IR damaged parotid glands from mice treated with IGF-1. by Jordan A. Gunning (18143970)

Flow cytometry plots and gating strategy for phagocytic immune cells from IR damaged parotid glands. by Jordan A. Gunning (18143970)

Flow cytometry plots and gating strategy for lymphocytes in IR damaged parotid glands. by Jordan A. Gunning (18143970)

Flow cytometry plots and gating strategy for phagocytic immune cells from IR damaged parotid glands in mice treated with IGF-1. by Jordan A. Gunning (18143970)

S1 Data - by Jordan A. Gunning (18143970)

“…Specifically, total immune cells (CD45+) decrease at days 2 and 5 following IR, macrophages (F4/80+CD11b+) decrease at day 2 and 5 and increase at day 30, while neutrophils (Ly6G+CD11b+) significantly increase at day 30 following IR. …”

Spontaneous oxycodone withdrawal initially flattens NREM power rhythms, decreases low frequency and increases high frequency power. by Michael Gulledge (20577135)

Color data collection points on the body of ornamental shrimp. by Wei-Wei Hou (3405947)

FGF18 injections increase TIMP1 and decrease MMP13 and NOGGIN, suggesting healing of degeneration induction of anabolic effect. by Flavia Gomes Velasque Gama (21175112)

Structural details for each point mutation studied by X-ray crystallography in this study. by Aleksi Sutinen (10039145)

Subjects:

Stacked bar plots of predicted absolute IPD cases per year from 2006 to 2031 in Germany for three different age groups (<2y, 16-59y, ≥60y). by Matthias Horn (78815)

Depletion of <i>cyd-1</i> leads to decreased oocyte quality and increased apoptosis without affecting the DNA damage response (DDR). by Umanshi Rautela (20235283)

MMP-2 production is decreased following ALK5 inhibition. by Rebecca A. Scott (488956)

Brain and liver GCase activity are significantly decreased in heterozygous <i>GBA1</i> D409V KI mice, with varying differences in glucosphingolipid lipids in brain and liver. by Nicole K. Polinski (10947787)

“…(A-B) GCase levels as assessed by the CBE/4-MU method are significantly decreased in the het <i>GBA1</i> D409V KI mice at 5 months of age in both brain (A) and liver (B). …”

GCase activity is significantly decreased in the brain and liver of the homozygous <i>GBA1</i> D409V KI mouse model at 4, 8, and 12 months of age. by Nicole K. Polinski (10947787)

“…In whole brain homogenate (A,C) and liver homogenate (B,D), GCase activity is significantly decreased in the <i>GBA1</i> D409V KI homozygous (HOM) mice as compared to C57Bl/6 wild type (WT) mice (n = 7/group). …”