The NH₂-terminus of PDX-1 binds to <i>Krt19</i> promoter DNA. by Johannes von Burstin (243524)

“…C) MIN6 cells were transfected with V5-tagged full length PDX-1 or PDX-1 Δ1-37. DNA precipitation was carried out as described above, and membranes were probed with anti-V5. …”

Psychiatric evaluation and personality in psoriasis patients by Hacer Akgül Ceyhun (22747079)

“…In psoriasis patients with a psychiatric diagnosis, Plasticity, and Openness to experience personality traits scores showed a significant decrease with a medium effect size. …”

Land-use changes affect the functional structure of stream fish assemblages in the Brazilian Savanna by Ludmilla R. P. Alvarenga (12682514)

Endovascular revascularization of TASC C and D femoropopliteal occlusive disease using carbon dioxide as contrast by Cynthia de Almeida Mendes (10407739)

GJ inhibition is the key driver of single-cell Ca²⁺ spike activity. by Dharsan K. Soundarrajan (11632145)

“…<b>(B-E)</b> <i>K</i>_<i>PLC</i> is increased left-to-right (red bar), and gap junction communication is decreased left-to-right (blue bar). An increase in <i>K</i>_<i>PLC</i> results in a decrease in frequency, while decrease in gap junction communication results in single-cell Ca²⁺ spikes (red arrows).…”

<i>Drosophila</i> peroxisomal gene networks. by Michael F. Wangler (544124)

“…These <i>Drosophila</i> peroxisomal genes are clustered in 5 co-regulated gene clusters that were subsequently used to identify the top 1000 genes for each cluster that has a similar expression pattern from <i>Drosophila</i> gene expression data-sets. …”

Aerofoil Design for Unmanned High-Altitude Aft-Swept Flying Wings by Ahmad Abdulkarim Alsahlan (4659976)

“…The second part contains the optimisation code using a genetic algorithm. The primary target here was to design a number of aerofoils with low pitching moment, suitable for an aft-swept flying wing configuration operating at low Reynolds number in the range of about 0.5 × 106. …”

SCS Designs 6, 7, and 8. by Matthew R. Lakin (649454)

“…We tested various lengths for the substrate binding arms of the upstream DNAzyme (denoted as 5′/3′ in the Figure). These results showed that longer substrate binding arms decrease the effect on activation rate by reducing the rate of product dissociation. …”

Data_Sheet_1_SUMOylation of Alpha-Synuclein Influences on Alpha-Synuclein Aggregation Induced by Methamphetamine.doc by Lin-nan Zhu (5681939)

“…Levels of the ubiquitin-proteasome system (UPS)-related makers ubiquitin (Ub) and UbE1, as well as the autophagy-lysosome pathway (ALP)-related markers LC3, P62 and lysosomal associated membrane protein 2A (LAMP2A), were also measured in SH-SY5Y cells transfected with lentivirus and mice injected with adenovirus. …”

Image_2_P300/CBP Associated Factor (PCAF) Deficiency Enhances Diet-Induced Atherosclerosis in ApoE3*Leiden Mice via Systemic Inhibition of Regulatory T Cells.JPEG by Alwin de Jong (4012250)

“…Expression of FoxP3 by systemic CD4⁺ T cells decreased 1.8 fold in ApoE3^*LeidenxPCAF^−/− after 5 months HFD and remained significantly reduced after 5 months of HFD. …”

Molecular Characterization of Acquired Tolerance of Tumor Cells to Picropodophyllin (PPP) by Jamileh Hashemi (131207)

“…Using Nexus software analysis we combined the array-CGH data with data from gene expression profilings and identified genes that were altered in both inputs. A subset of genes identified as downregulated (<em>ALDH1A3</em>, <em>ANXA1</em>, <em>TLR4</em> and <em>RAB5A</em>) or upregulated (<em>COX6A1</em>, <em>NFIX</em>, <em>ME1</em>, <em>MAPK</em> and <em>TAP2</em>) were validated by siRNA in the tolerant or parental cells to alter sensitivity to PPP and confirmed to alter sensitivity to PPP in further cell lines.…”

Metabolomics raw data and table of extracted peak areas for BT478, BT530 and NHA cells cultured in the presence of MPA, Compound 3 (IC80) or vehicle control, for 6 hours. by Agata Monika Kieliszek (14650298)

“…The linear gradient employed was as follows: 0–2.5 min 99% A, 2.5–7.5 min decrease to 80% A, 7.5–13 min to 55% B 652 and finally 13–15 min to 99% B and held for 1 min. …”

Table_1_Regulation of miRNA expression in the prefrontal cortex by fecal microbiota transplantation in anxiety-like mice.docx by Simin Chen (9549665)

“…MiRNA analysis identified five key miRNAs affecting GAD pathogenesis, including mmu-miR-10a-5p, mmu-miR-1224-5p, mmu-miR-218-5p, mmu-miR-10b-5p, and mmu-miR-488-3p. …”

Image_1_P300/CBP Associated Factor (PCAF) Deficiency Enhances Diet-Induced Atherosclerosis in ApoE3*Leiden Mice via Systemic Inhibition of Regulatory T Cells.JPEG by Alwin de Jong (4012250)

“…Expression of FoxP3 by systemic CD4⁺ T cells decreased 1.8 fold in ApoE3^*LeidenxPCAF^−/− after 5 months HFD and remained significantly reduced after 5 months of HFD. …”

Characterizing PIPPET’s behavior at events. by Jonathan Cannon (5665774)

“…<p>A) An event is expected at phase <i>ϕ</i>₁ = 0.5 with variance <i>v</i>₁ and expectation strength λ₁. …”

Increase of ADAMTS1 mRNA correlated with reduction of ADAMTS1 promoter-associated H3K27me3 and EZH2 binding through passages. by Shiaw-Wei Tyan (171220)

“…<p>(A) ADAMTS1 mRNA levels in indicated NAF derivatives were analyzed and shown gradually increased in NAF 200N.E4 from P0 to P3 and maintained from P3 to P5. …”

The STIM2-TM domain activates the cytosolic region of STIMs less efficiently than that of STIM1. by Sisi Zheng (1574473)

“…Left: average time course of whole-cell I_CRAC currents measured at –100 mV. Currents mediated by STIM1121-ΔK developed significantly more slowly than control (time to peak, 72 ± 7 s versus 147 ± 9 s, <i>n</i> = 7, ****<i>P</i> < 0.0001, <i>t</i> test), with the maximal current density also reduced (–5.5 ± 0.8 pA/pF versus –1.5 ± 0.1 pA/pF, <i>n</i> = 7, *****<i>P</i> < 0.0004, <i>t</i> test). …”

Similarity of samples with prior and posterior during conflict. by Sarah Schwöbel (18981093)

“…Hence, for lower values of <i>s</i>, the samples in the chain correspond more closely to the prior, which means that for shorter reaction times (e.g. the beige bars in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1012228#pcbi.1012228.g005" target="_blank">Fig 5H</a>) the chosen policy and corresponding action will be determined by the prior, and therewith automatic. …”

Redox couples altered lipolysis. by Albert R. Jones IV (513761)

“…Forskolin (5 μM) was used as a positive control (not shown). …”

Granzyme B was secreted by NK-92 cells and penetrated into CNE-1 cells during co-culture. by Kai-Lin Yang (407300)

“…(C) DCIC pretreated with CNE-1 cells for 1 h, then co-cultured with 2.5 fold of NK92 cells for 4 h. After washing NK92 cells away, and CNE-1 cells were exposed to 800 cGy of radiation and analyzed for the ratio procaspase/caspase-3 by ImageJ (a decreased ratio is indicative of apoptosis). …”