HCV-induced chronic ER stress confers resistance to drug induced UPR. by Emmanuelle Merquiol (204704)

“…<p>HCV infected cells were stimulated by decreasing doses of thapsigargin at day 5 and at day 14 post infection and the effect of stimulation on (a) XBP-1 splicing or (b) IRE1 and (c) eIF2α phosphorylation was assessed by RT-PCR and immunoblotting respectively. …”

Data_Sheet_1_Whole Body Vibration Improves Spatial Memory, Anxiety-Like Behavior, and Motor Performance in Aged Male and Female Rats.pdf by Tamás Oroszi (11983592)

“…WBV-treated rats showed a decrease in their anxiety level in the open field test compared with those in the pseudo-treated controls. …”

Transcriptomics insight into occupational exposure to engineered nanoparticles by Zuzana Simova (19368296)

“…</p> <p>Following PM0.1 exposure, a significant decrease in the expression of <i>DDIT4</i> and <i>FKBP5</i>, genes involved in the stress response, was detected in exposed workers. …”

Glomerular-specific innervation pattern of the CSDn in the AL is regulated by Ephrin. by Ajeet Pratap Singh (404076)

“…(B-B″, F) In <i>Ephrin^KG09118</i> hypomorphs, increased terminal innervations can be seen to VA1l/m (n = 5, p<0.001), DA1 (n = 5, p<0.001) and DL3 (n = 9, p = 0.018) while innervations in VA1d (n = 5, p = 0.865) and V (n = 4, p = 0.149) are comparable to controls. …”

Chromatin conformation and bound CTCF sites at the mouse and chick <i>HoxD</i> locus. by Nayuta Yakushiji-Kaminatsui (6008795)

“…(E, F) Subtraction of the CHi-C matrices shown in (B) between the <i>HoxD</i> cluster and the area from region a to region b within T-DOM at a 5-kb resolution. …”

Role of MSLN in cellular growth, cell cycle progression and apoptosis, following treatment with chemotherapeutic drugs. by Ombretta Melaiu (511640)

“…<p><i>A</i>. Proliferation assay in Mero-14 cells. The graph shows the effect of the treatments with 5 µM cisplatin and 40 nM siMSLN-1, used as single agents or in combination. …”

Role of Duplicate Genes in Robustness against Deleterious Human Mutations by Tzu-Lin Hsiao (42604)

“…The contribution of close sequence homologs to genetic robustness against null mutations has been previously demonstrated in simple organisms <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000014#pgen.1000014-Gu1">[4]</a>,<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000014#pgen.1000014-Conant1">[5]</a>. …”

Supplementary file 1_Persistent burden and health inequalities of disease in women of childbearing age attributable to Intimate Partner Violence, 1990–2021.docx by Yingda Song (15410321)

“…The absolute value of the SII for ASMR increased from 2.04 in 1990 to 4.59 in 2021, while that of the SII for ASDR decreased from 321 in 1990 to 190 in 2021. The relative Concentration Index for ASMR and ASDR dropped from -0.33 and -0.2 in 1990 to -0.46 and -0.26 in 2021, respectively. …”

Table_2_Differential effects on TDP-43, piezo-2, tight-junction proteins in various brain regions following repetitive low-intensity blast overpressure.DOCX by Lanier Heyburn (7055039)

“…</p>Methods<p>In this study, using a rodent model of relBOP and western blotting for protein expression we showed the differential expression of various neuropathological proteins like TDP-43, tight junction proteins (claudin-5, occludin, and glial fibrillary acidic protein (GFAP)) and a mechanosensitive protein (piezo-2) in different regions of the brain at different intensities and frequency of blast.…”

Overall model framework. by Ke Yan (331581)

“…On the other hand, taking English writing teaching as an example, the proposed method is further verified by designing a comparative experiment in groups. The results show that: (1) From the experimental data of word sense disambiguation, the accuracy of the SMOSS-LSTM model proposed in this paper is the lowest when the context range is "3+3", then it rises in turn at "5+5" and "7+7", reaches the highest at "7+7", and then begins to decrease at "10+10"; (2) Compared with the control group, the accuracy of syntactic analysis in the experimental group reached 89.5%, while that in the control group was only 73.2%. (3) In the aspect of English text error detection, the detection accuracy of the proposed model in the experimental group is as high as 94.8%, which is significantly better than the traditional SMOSS-based text error detection method, and its accuracy is only 68.3%. (4) Compared with other existing researches, although it is slightly inferior to Bidirectional Encoder Representations from Transformers (BERT) in word sense disambiguation, this proposed model performs well in syntactic analysis and English text error detection, and its comprehensive performance is excellent. …”

Table_3_Differential effects on TDP-43, piezo-2, tight-junction proteins in various brain regions following repetitive low-intensity blast overpressure.DOCX by Lanier Heyburn (7055039)

“…</p>Methods<p>In this study, using a rodent model of relBOP and western blotting for protein expression we showed the differential expression of various neuropathological proteins like TDP-43, tight junction proteins (claudin-5, occludin, and glial fibrillary acidic protein (GFAP)) and a mechanosensitive protein (piezo-2) in different regions of the brain at different intensities and frequency of blast.…”

Presentation4_Estimation of the P Fertilizer Demand of China Using the LePA Model.PPTX by Wenjia Yu (9422059)

“…We used the legacy P assessment model (LePA) to estimate P demand based on soil P management at the county, regional, and country scales according to six P application rate scenarios: (1) rate in 2012 maintained; (2) current rate maintained in low-P counties and P input stopped in high-P counties until critical Olsen-P level (CP) is reached, after which rate equals P-removal; (3) rate decreased to 1–1.5 kg ha⁻¹ year⁻¹ in low-P counties after CP is reached and in high-P counties; (4) rate in each county decreased to 1–8 kg ha⁻¹ year⁻¹ after soil Olsen-P reached CP in low P counties; (5) rate in each county was kept at P-removal rate after reduction; (6) P input was kept at the rate lower than P-offtake rate after reduction. …”

Presentation3_Estimation of the P Fertilizer Demand of China Using the LePA Model.PPTX by Wenjia Yu (9422059)

“…We used the legacy P assessment model (LePA) to estimate P demand based on soil P management at the county, regional, and country scales according to six P application rate scenarios: (1) rate in 2012 maintained; (2) current rate maintained in low-P counties and P input stopped in high-P counties until critical Olsen-P level (CP) is reached, after which rate equals P-removal; (3) rate decreased to 1–1.5 kg ha⁻¹ year⁻¹ in low-P counties after CP is reached and in high-P counties; (4) rate in each county decreased to 1–8 kg ha⁻¹ year⁻¹ after soil Olsen-P reached CP in low P counties; (5) rate in each county was kept at P-removal rate after reduction; (6) P input was kept at the rate lower than P-offtake rate after reduction. …”

Key parameters of LSTM training model. by Ke Yan (331581)

“…On the other hand, taking English writing teaching as an example, the proposed method is further verified by designing a comparative experiment in groups. The results show that: (1) From the experimental data of word sense disambiguation, the accuracy of the SMOSS-LSTM model proposed in this paper is the lowest when the context range is "3+3", then it rises in turn at "5+5" and "7+7", reaches the highest at "7+7", and then begins to decrease at "10+10"; (2) Compared with the control group, the accuracy of syntactic analysis in the experimental group reached 89.5%, while that in the control group was only 73.2%. (3) In the aspect of English text error detection, the detection accuracy of the proposed model in the experimental group is as high as 94.8%, which is significantly better than the traditional SMOSS-based text error detection method, and its accuracy is only 68.3%. (4) Compared with other existing researches, although it is slightly inferior to Bidirectional Encoder Representations from Transformers (BERT) in word sense disambiguation, this proposed model performs well in syntactic analysis and English text error detection, and its comprehensive performance is excellent. …”

DataSheet1_Estimation of the P Fertilizer Demand of China Using the LePA Model.xlsx by Wenjia Yu (9422059)

“…We used the legacy P assessment model (LePA) to estimate P demand based on soil P management at the county, regional, and country scales according to six P application rate scenarios: (1) rate in 2012 maintained; (2) current rate maintained in low-P counties and P input stopped in high-P counties until critical Olsen-P level (CP) is reached, after which rate equals P-removal; (3) rate decreased to 1–1.5 kg ha⁻¹ year⁻¹ in low-P counties after CP is reached and in high-P counties; (4) rate in each county decreased to 1–8 kg ha⁻¹ year⁻¹ after soil Olsen-P reached CP in low P counties; (5) rate in each county was kept at P-removal rate after reduction; (6) P input was kept at the rate lower than P-offtake rate after reduction. …”

Pdi1 is essential for fungal growth within the maize plant. by Miriam Marín-Menguiano (180236)

“…<i>maydis</i> hyphae with WGA-AF-488 (green), and visualized by fluorescence microscopy, showing a decrease in the growth and branching capability of the <i>pdi1</i> mutant. …”

Presentation2_Estimation of the P Fertilizer Demand of China Using the LePA Model.PPTX by Wenjia Yu (9422059)

“…We used the legacy P assessment model (LePA) to estimate P demand based on soil P management at the county, regional, and country scales according to six P application rate scenarios: (1) rate in 2012 maintained; (2) current rate maintained in low-P counties and P input stopped in high-P counties until critical Olsen-P level (CP) is reached, after which rate equals P-removal; (3) rate decreased to 1–1.5 kg ha⁻¹ year⁻¹ in low-P counties after CP is reached and in high-P counties; (4) rate in each county decreased to 1–8 kg ha⁻¹ year⁻¹ after soil Olsen-P reached CP in low P counties; (5) rate in each county was kept at P-removal rate after reduction; (6) P input was kept at the rate lower than P-offtake rate after reduction. …”

Comparison chart of model evaluation results. by Ke Yan (331581)

“…On the other hand, taking English writing teaching as an example, the proposed method is further verified by designing a comparative experiment in groups. The results show that: (1) From the experimental data of word sense disambiguation, the accuracy of the SMOSS-LSTM model proposed in this paper is the lowest when the context range is "3+3", then it rises in turn at "5+5" and "7+7", reaches the highest at "7+7", and then begins to decrease at "10+10"; (2) Compared with the control group, the accuracy of syntactic analysis in the experimental group reached 89.5%, while that in the control group was only 73.2%. (3) In the aspect of English text error detection, the detection accuracy of the proposed model in the experimental group is as high as 94.8%, which is significantly better than the traditional SMOSS-based text error detection method, and its accuracy is only 68.3%. (4) Compared with other existing researches, although it is slightly inferior to Bidirectional Encoder Representations from Transformers (BERT) in word sense disambiguation, this proposed model performs well in syntactic analysis and English text error detection, and its comprehensive performance is excellent. …”

DataSheet1_The IRE1α Inhibitor KIRA6 Blocks Leukotriene Biosynthesis in Human Phagocytes.docx by Xiao Tang (801264)

“…However, we find that KIRA6 dose-dependently blocks phosphorylation of p38 and ERK, mitogen-activated protein kinases (MAPKs) that have established roles in activating cytosolic PLA₂α (cPLA₂α) and 5-LOX. The reduction of p38 and ERK phosphorylation is associated with a decrease in cPLA₂α phosphorylation and attenuated leukotriene production. …”

Table_1_Differential effects on TDP-43, piezo-2, tight-junction proteins in various brain regions following repetitive low-intensity blast overpressure.XLSX by Lanier Heyburn (7055039)

“…</p>Methods<p>In this study, using a rodent model of relBOP and western blotting for protein expression we showed the differential expression of various neuropathological proteins like TDP-43, tight junction proteins (claudin-5, occludin, and glial fibrillary acidic protein (GFAP)) and a mechanosensitive protein (piezo-2) in different regions of the brain at different intensities and frequency of blast.…”