A σ^E-Mediated Temperature Gauge Controls a Switch from LuxR-Mediated Virulence Gene Expression to Thermal Stress Adaptation in <i>Vibrio alginolyticus</i> by Dan Gu (2191075)

“…An <i>rpoE</i> null <i>V</i>. <i>alginolyticus</i> mutant was unable to adapt to various stresses and was survival-deficient in fish. …”

An idealized view of the opportunity provided by a comparative and integrated oncology drug development path. by Ira Gordon (369869)

“…Factoring in additional costs for comparative studies with this approach of US$150,000 for studies conducted in the preclinical setting, US$250,000 for studies conducted before or during Phases I–II human trials and US$1 million for studies conducted before Phases II–III studies, the total cost of development is estimated at US$2.07 billion. The result may be a decrease in average clinical trial costs per approved drug from US$290 million to US$173 million <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1000161#pmed.1000161-Adams1" target="_blank">[5]</a>.…”

Changes in Dietary Fat Intake and Projections for Coronary Heart Disease Mortality in Sweden: A Simulation Study by Lena Björck (77400)

“…We assumed that there would be moderate improvements in smoking (5%), salt intake (1g/day) and physical inactivity (5% decrease) to continue recent, positive trends.…”

The changing trends of <i>f</i>_<i>i</i>, <i>i</i> ∈ {1, 2, 3, 4} with <i>v</i> for the Moran process (first row) and the Wright-Fisher process (second row) when <i>u</i>... by Yanling Zhang (6561)

“…For all <i>r</i>, The curve of <i>f</i>₄ with <i>v</i> (fourth column) has an increasing trend with a small perturbation near <i>v</i> = 0.01. …”

Data_Sheet_1_Expression of vitamin D receptor, CYP24A1, and CYP27B1 in normal and inflamed canine pancreases.DOCX by Dohee Lee (432106)

“…This study showed that VDR expression decreased in inflamed pancreases and demonstrated CYP24A1 and CYP27B1 expression in the canine pancreas for the first time. …”

Core–Shell {Mn₇⊂(Mn,Cd)₁₂} Assembled from Core {Mn₇} Disc by Ling-Yu Guo (3068232)

“…HR-ESI-MS was even more precise by revealing three prominent molecular species, Mn₁₃Cd₆, Mn₁₄Cd₅ and Mn₁₅Cd₄, having a distribution of metals. …”

Table_1_Treatment of multiple sclerosis with rituximab: A Spanish multicenter experience.DOCX by Francisco Gascón-Giménez (12266840)

“…Mean EDSS had increased from 4.3 (SD: 1.9) to 4.8 (SD: 1.7) and almost half of the patients (41%) had worsened at least one point. After a median follow-up of 14.2 months (IQR: 6.5–27.2), ARR decreased by 85.7% (p < 0.001) and GEL by 82.9%, from 0.41 to 0.07 (p < 0.001). …”

Resource consumption of multi-substance users in the emergency room: A neglected patient group by Laurence Klenk (7434560)

“…<div><p>Background</p><p>Multi-substance use is accompanied by increased morbidity and mortality and responsible for a large number of emergency department (ED) consultations. …”

Table_1_Treatment of multiple sclerosis with rituximab: A Spanish multicenter experience.DOCX by Francisco Gascón-Giménez (12266840)

“…Mean EDSS had increased from 4.3 (SD: 1.9) to 4.8 (SD: 1.7) and almost half of the patients (41%) had worsened at least one point. After a median follow-up of 14.2 months (IQR: 6.5–27.2), ARR decreased by 85.7% (p < 0.001) and GEL by 82.9%, from 0.41 to 0.07 (p < 0.001). …”

Data Sheet 1_Effects of a polyphenol-rich extract blend, probiotics, and hydrolyzed fiber on quality of life and gut health markers in patients with irritable bowel syndrome—A rand... by Adrianna Wierzbicka (14130159)

“…Introduction<p>Irritable bowel syndrome (IBS) is the most prevalent functional bowel disorder impacting around 5%−10% of the general population worldwide. The pathogenesis remains unclear, however alterations in gut-brain axis play a critical role. …”

Application of product development tools in equipment design for a technology-based small business by Felipe Mello Pierobom (10396580)

A simplified methodology for the analysis of the establishment of hydrokinetic parks downstream from hydroelectric plants by Paulo André Vasco Barbosa (5342219)

High mRNA expression of <i>Slc6a15</i> in CNS. by Maria G. A. Hägglund (386708)

DataSheet1_Examining the paradoxical effects of kratom: a narrative inquiry.PDF by Kirsten E. Smith (10716529)

“…Five of the 10 participants met DSM-5-based criteria for kratom-use disorder (3 mild, 1 moderate, 1 severe, by symptoms counts). …”

Table 1_A retrospective analysis of 38,652 amniotic fluid karyotype.xlsx by Jianyu Ren (11429773)

“…Chromosome breakage was most common in chromosomes Y and 1, whereas deletions were most frequently detected in chromosomes X and 5. Isochromosomes mainly appeared in a mosaic form in chromosome X. …”

Supplementary Material for: Urinary Apolipoprotein C3 Is a Potential Biomarker for Alzheimer’s Disease by Watanabe Y. (4129684)

“…We previously reported on the comprehensive profile of the urinary proteome of AD patients and identified proteins estimated to be significantly increased or decreased in AD patients by a label-free quantification method. …”

Effects of the AMPA Antagonist ZK 200775 on Visual Function: A Randomized Controlled Trial by Richard Bergholz (244473)

“…<div><h3>Background</h3><p>ZK 200775 is an antagonist at the α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor and had earned attention as a possible neuroprotective agent in cerebral ischemia. …”

Speed of processing training and depression in assisted and independent living: A randomized controlled trial by Marianne Smith (7512284)

“…Participants were randomized within sites to computerized SOPT vs. computerized crossword puzzles with a targeted dose of 10 hours of playtime at baseline plus 4 hours of booster training at five and eleven months. …”

Table 1_Obinutuzumab in systemic lupus erythematosus: a real-world experience.docx by Chunmei Wu (3202050)

“…</p>Methods<p>We retrospectively analyzed 56 SLE patients who received a single dose of obinutuzumab (1000 mg) at Renji Hospital, Shanghai Jiao Tong University School of Medicine between October 2021 and March 2024. …”

RPIA regulates colon cell proliferation through β-catenin expression in HCT116 cells. by Yu-Ting Chou (447778)

“…<i>AXIN2</i>, <i>Axis inhibition protein 2</i>; <i>CCND1</i>, <i>Cyclin D1</i>; <i>CCNE2</i>, <i>Cyclin E2</i>; <i>CTNNB1</i>, <i>CATENIN BETA 1</i>; pcDNA, pcDNA3 vector control; qPCR, quantitative PCR; RPIA, ribose-5-phosphate isomerase A; si-NC, negative control small interfering RNA; si-RPIA, RPIA small interfering RNA; TCF, T-cell transcription factor.…”