The use of urinary proteomics in the assessment of suitability of mouse models for ageing by Esther Nkuipou-Kenfack (562346)

“…In mice and humans, a decrease in urinary excretion of fibrillar collagens and an increase of uromodulin fragments was observed with advanced age. …”

Data_Sheet_1_Intensity and lag-time of non-pharmaceutical interventions on COVID-19 dynamics in German hospitals.PDF by Yvette Montcho (14722117)

“…</p>Results and discussion<p>Our findings show that the first reducing effect of non-pharmaceutical interventions on the number of prevalent intensive care patients before vaccination can be expected not before a time lag of 5 days; the main effect is after a time lag of 10–15 days. …”

Depletion of METTL3 leads to slower proliferation in MEFs. by Hui Xian Poh (13118985)

“…(<b>B</b>) <i>Mettl3</i> knockout in MEFs leads to a decrease in cellular proliferation. Using an MTT assay, we measured cell proliferation after 4OHT-induced <i>METTL3</i> knockout over 8 days. …”

Suppressing TLR4 alleviates cerebral injury in heatstroke rats through the modulation of microglial polarization by Xiaomin Wu (20328165)

“…</p><p dir="ltr"><b>Methods:</b><b> </b>We established a HS rat model by placing rats in a controlled artificial climate chamber at a temperature of 40±0.5°C until their rectal core temperature (Tc) reached 42°C, which is the established threshold for diagnosing HS. …”

TPCA-1 inhibits NF-κB signaling pathway and the thermal injury-induced angiogenesis-associated factors. by Huayi Lu (424662)

“…<p>(A) TPCA-1 inhibits the TNFα-induced κB-Luciferase activity in a dosage dependent manner. 293T cells containing κB-Luciferase reporter were pretreated with or without TPCA1 for 30 minutes, then stimulated with 10 ng/mL TNFα to induce κB-Luciferase expression in the presence of the indicated amount of TPCA-1 for 5 hours, and followed by cell lysis and luciferase assay. …”

<em>In Vitro</em> Effects of Pirfenidone on Cardiac Fibroblasts: Proliferation, Myofibroblast Differentiation, Migration and Cytokine Secretion by Qiang Shi (191722)

“…Several studies have illustrated that pirfenidone (5-methyl-1-phenyl-2-[1H]-pyridone) attenuates cardiac fibrosis in different animal models. …”

CHNRI's Conceptual Framework by Olivier Fontaine (226878)

Public and private health expenditures in Brazil and selected countries by Juliana Oliveira Figueiredo (4748232)

Smn deficiency in SMA type I axon terminals <i>in</i><i>vivo.</i> by Benjamin Dombert (648183)

“…Acetylcholine receptors (AChR) and postsynaptic nuclei were visualized by ω-BTX and DAPI, respectively (scale bar: 5 µm). In (A) Smn deficiency is visible by highly reduced immunoreactive signals, as highlighted in the white box, whereas in (B) the number of Smn particles per NMJ is decreased in SMA type I motor endplates, as indicated by white arrowheads. …”

DataSheet1_Anti-Obesity and Lipid Lowering Activity of Bauhiniastatin-1 is Mediated Through PPAR-γ/AMPK Expressions in Diet-Induced Obese Rat Model.xlsx by Reddy Sankaran Karunakaran (11171955)

“…In animal experiments, rats were divided into Group-I: normal pellet diet-fed, Group-II: HFD-fed, Groups-III, IV and V: HFD-fed BSTN1 (1.25, 2.5, and 5 mg/kg.b.wt./day/rat)-treated and Group-VI: HFD-fed Orlistat-treated. …”

Table_1_Effects of urea topdressing time on yield, nitrogen utilization, and quality of mechanical direct-seeding hybrid indica rice under slow-mixed fertilizer base application.do... by Yongjian Sun (1787704)

“…However, Fyou 498 showed a significant decrease in the head rice rate and taste value by 3.34–7.67%. …”

Image_1_Effects of urea topdressing time on yield, nitrogen utilization, and quality of mechanical direct-seeding hybrid indica rice under slow-mixed fertilizer base application.pd... by Yongjian Sun (1787704)

“…However, Fyou 498 showed a significant decrease in the head rice rate and taste value by 3.34–7.67%. …”

Topographic map of study area in interior Alaska by Dana R Nossov (557153)

“…On average, fire caused a five-fold decrease in mean surface organic layer thickness, a doubling of water storage in the active layer, a doubling of thaw depth, an increase in soil temperature at the surface (−0.6 to +2.1 ° C) and at 1 m depth (−1.7 to +0.4 ° C), and a two-fold increase in net soil heat input. …”

PKM2 Subcellular Localization Is Involved in Oxaliplatin Resistance Acquisition in HT29 Human Colorectal Cancer Cell Lines by Alba Ginés (2211217)

“…By using trypan blue stain and FITC-Annexin V/PI tests we detected that PKM2 knockdown was associated with an increase in cell viability but not with a decrease in apoptosis activation in HT29 cells. …”

Unexpired ITNs distributed by Global Fund-supported programs in sub-Saharan Africa, 2005 to 2015. by Itamar Katz (229214)

“…ITNs to be distributed in 2010 will expire by 2014, and because less ITNs projected to be distributed in 2014 compared to 2010, a decrease is expected between 2013 and 2014.</p>…”

Light pulses of different wavelengths differ in triggering fluorescence quenching. by Tobias Pfennig (19658783)

“…For the measurement, 1.5 mL culture was transferred to a quartz cuvette and dark-acclimated for 5 min prior to each measurement. …”

Neonatal Maternal Deprivation Response and Developmental Changes in Gene Expression Revealed by Hypothalamic Gene Expression Profiling in Mice by Feng Ding (33360)

“…Unlike in adult rodents, expression levels of <em>Nanos2</em> and <em>Pdk4</em> were increased, and those of <em>Pgpep1</em>, <em>Ndp</em>, <em>Brms1l</em>, <em>Mett10d</em>, and <em>Snx1</em> were decreased after neonatal deprivation. In addition, we compared hypothalamic gene expression profiles at postnatal days 5 and 13 and observed significant developmental changes. …”

Concentration-dependence of the transcriptome response to IL-3. by Donald MacGlashan Jr. (736839)

“…Two groups were derived from SIL3-51T, those that increased with IL-3 (●, n = 34) and those that decreased with IL-3 (■, n = 17). The third group (○) are transcripts that increase greater than 5 fold at the 10 ng/ml IL-3 concentration. …”

Land-use affecting organic carbon and its active components in soil aggregates in China by Xiaoqian Liu (154284)

miR-152-3p aggravates vascular endothelial cell dysfunction by targeting DEAD-box helicase 6 (DDX6) under hypoxia by Zhongyan Zhao (11254731)