Embryonic <i>Cul4b</i> is important for epiblast growth and location of primitive streak layer cells by Chun-Yu Chen (486495)

“…First, we show that the loss of embryonic <i>Cul4b</i> affects the growth of the inner cell mass <i>in vitro</i> and delays epiblast development during the gastrulation period at E6.5~E7.5 <i>in vivo</i>, as highlighted by the absence of the epiblastic transcription factor <i>Brachyury</i> from E6.5~E7.5. …”

Data_Sheet_1_Sleep in 21-Day Dry Immersion. Are Cardiovascular Adjustments Rapid Eye Movement Sleep-Dependent?.docx by Evgeny Yu. Bersenev (11605863)

Fetal growth standards for Somali population by Hiba J. Mustafa (7417595)

Meta-Analysis of Pulmonary Artery Denervation for Treatment of Pulmonary Hypertension by Wanyun Zuo (10650563)

“…Meta-analysis showed that after PADN, mPAP (mean difference [MD] -12.51, 95% confidence interval [CI] -17.74 to -7.27, P<0.00001) (mmHg) and PVR (MD -5.17, 95% CI -7.70 to -2.65, P<0.0001) (Wood unit) decreased significantly, CO (MD 0.59, 95% CI 0.32 to 0.86, P<0.0001) (L/min) and 6MWD (MD 107.75, 95% CI 65.64 to 149.86, P<0.00001) (meter) increased significantly, and RV Tei index (MD -0.05, 95% CI -0.28 to 0.17, P=0.63) did not change significantly. …”

Age-dependent evolution. by Simon Ammanuel (804366)

“…Difference in delta power between Control EEGs and RTT EEGs seems to be driven by 2–5 year age group. (B) Gamma power in control group had a significant decrease from age group 2–5 year to 6–9 year group. …”

COPI-Dependent Golgi Disassembly in DCV Infected Cells by Sara Cherry (170695)

“…</p><p>(B–F) Loss of COPI <i>(bCOP)</i> (B), <i>SREBP</i> (E), or <i>CG3523</i> (F) but not COPII <i>(sec23)</i> (C) or <i>Syx5</i> (D) results in a decrease in viral infection. …”

The expression of BDNF is reduced in the cerebral cortex and striatum of ceruloplasmin-deficient mice. by Sarah J. Texel (343929)

“…<p><b>A.</b> RT-PCR measures of the 4 BDNF transcripts show a decrease in BDNF transcripts 1, 2 and 4 in the cortex of the CpKO mouse (*p<0.04, n = 5). …”

Animals receiving unilateral cervical contusion SCI exhibited persistent thermal hyperalgesia and tactile allodynia in the forepaw. by Jaime L. Watson (636381)

“…In animals receiving C6 injury, but not C5 injury, a significant decrease compared to pre-injury baseline in the force threshold required to elicit a withdrawal response was evident both ipsilaterally (E) and contralaterally (F) for each of the six weeks following injury. …”

Immunofluorescence analysis of Kv1.4 subunit expression in hippocampus and cerebral cortex. by Patrizia Campolongo (410617)

“…Representative immunofluorescence photomicrographs showing Kv1.4 expression in <b>a</b>) hippocampus and <b>b</b>) frontal cortex after memory tests in the four experimental treatments: Control (Saline), Aβ_25–35-i.c.v. treated rats (Abeta), Aβ_25–35-i.c.v. and SP-i.p. treated rats (Abeta+SP), SP-i.p. treated rats (SP). …”

MEK1 interaction with PPARα induces nuclear export. by Hamid el Azzouzi (318740)

“…<p>(a) Western blot analysis on precipitates of HEK293 cells transiently co-transfected with PPARα-V5, MEK1 and treated with U0126 (5 µM) or not for 2 hr and immunoprecipitated using an anti-MEK1 antibody. …”

Supplementary movie 1 from Role of intracellular poroelasticity on freezing-induced deformation of cells in engineered tissues by Soham Ghosh (1319076)

“…Part 1, Time lapse video of a cell in suspension undergoing mean response dehydration. …”

Cytotoxicity of candidate agents to cholangiocarcinoma cells. by Chiara Braconi (235041)

“…All three compounds decreased cell viability in a concentration-dependent manner, with an IC50 for felodipine of 26±5 µM, nitrendipine, 44±10 µM and nifedipine, 15±4 µM. …”

Topical tacrolimus for the treatment of severe allergic keratoconjunctivitis in children by Vera Lucia Liendo (4657129)

“…Results: Analyses included 66 eyes of 33 patients. After a mean follow-up period of 13 months (range, 12-29 months), TCL treatment significantly decreased the mean symptom score severity for the right (from 5.56 ± 1.18 to 2.76 ± 1.5; p<0.001) and left (from 5.94 ± 1.16 to 2.86 ± 1.64; p<0.001). …”

PSTH histograms of the single population firing rate model during the simulated working memory task. by Sergio Verduzco-Flores (371239)

“…The baseline frequency is approximately 6 Hz, and at the beginning of the delay period the firing rate has decreased to approximately 2.5 Hz. The firing rate has returned to the baseline rate by the end of the delay period, mirroring the decaying memory cell activity observed in (A). …”

Exercise Training Attenuates Sympathetic Activity and Improves Morphometry of Splenic Arterioles in Spontaneously Hipertensive Rats by Marina de Paiva Lemos (4704679)

“…Exercise training attenuated mean AP only in SHRT (125.9 ± 6.2 mmHg) vs. SHRS (182.5 ± 4.2 mmHg, p < 0.001). …”

Deiodinase Knockdown during Early Zebrafish Development Affects Growth, Development, Energy Metabolism, Motility and Phototransduction by Enise Bagci (719720)

Image_1_Oral Trypanosoma cruzi Acute Infection in Mice Targets Primary Lymphoid Organs and Triggers Extramedullary Hematopoiesis.jpeg by Alessandro Marins-Dos-Santos (604437)

“…In parallel, our investigation provided clues that myeloid progenitor decrease could be associated with an atypical expression of Sca-1 in this population leading to a remarkable increase on LSK-like cells at 14 dpi within the HSPC compartment. …”

Image_4_Oral Trypanosoma cruzi Acute Infection in Mice Targets Primary Lymphoid Organs and Triggers Extramedullary Hematopoiesis.jpeg by Alessandro Marins-Dos-Santos (604437)

“…In parallel, our investigation provided clues that myeloid progenitor decrease could be associated with an atypical expression of Sca-1 in this population leading to a remarkable increase on LSK-like cells at 14 dpi within the HSPC compartment. …”

The Strong <i>In Vivo</i> Anti-Tumor Effect of the UIC2 Monoclonal Antibody Is the Combined Result of Pgp Inhibition and Antibody Dependent Cell-Mediated Cytotoxicity by Gábor Szalóki (631712)

“…However, this inhibition is partial, since UIC2 binds only to 10–40% of cell surface Pgps, while the rest becomes accessible to this antibody only in the presence of certain substrates or modulators (e.g. cyclosporine A (CsA)). The combined addition of UIC2 and 10 times lower concentrations of CsA than what is necessary for Pgp inhibition when the modulator is applied alone, decreased the EC₅₀ of doxorubicin (DOX) in KB-V1 (Pgp⁺) cells <i>in vitro</i> almost to the level of KB-3-1 (Pgp^-) cells. …”

Table_1_Impulsive choice in two different rat models of ADHD—Spontaneously hypertensive and Lphn3 knockout rats.DOCX by Monica S. Carbajal (14506454)