MSX-122 blocks metastasis in an experimental animal model of breast cancer metastasis. by Zhongxing Liang (173875)

“…<p>(A) Representative photographs of 5 lungs were shown from each group. …”

Triple-combination therapy for cutaneous leishmaniasis using detergent-free, hyaluronate-coated elastic nanovesicles - Supplementary data set by Kashif Iqbal (6504587)

“…Materials & methods: H-ENVs were</p> <p>developed and evaluated for vesicle size, entrapment efficiency, skin permeation and antileishmanial</p> <p>potential. Results: A 15.7 and 28.6% decrease in the cytotoxicity of paromomycin and amphotericin B,</p> <p>respectively, was observed in detergent-free ENVs compared with conventional ENVs. …”

Hypoxia downmodulates TM9SF4 expression in leukemic cells. by Rosa Paolillo (736953)

“…<p>(A, B) The decrease of TM9SF4 protein expression in U937 cells (A) and in primary leukemic cells from AML M1 (B) cultured under hypoxic (1% and 5% O₂, respectively) compared to normoxic (21% O₂) conditions is shown by immunofluorescence analysis of TM9SF4. ctr- is for no primary antibody negative control. …”

Effect of exponential smoothing on recombination and identity signals along the chromosome. by Mauricio Peñuela (7138847)

“…The horizontal red line is a reference that helps to visualize the decrease of large recombination values. …”

Developmental changes in the effect of cholinergic, inhibitory and L-type voltage-gated calcium channel-dependent networks on spontaneous activity. by Abduqodir H. Toychiev (477678)

“…In contrast, regenerative compound activity revealed by SST is more prominent with age, as BC axons and inhibitory inputs mature and spontaneous currents decrease (C, red and black traces). This transition is most prominent in late second postnatal week (see text and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0077658#pone-0077658-t001" target="_blank">Table 1</a> for details). …”

Capacitance changes in response to varying proton concentrations. by Armando Carpaneto (242436)

“…Increasing the proton concentration from pH 4 to 3 at −20 mV led to a decrease of C_m as well. Subsequent application of saturating sucrose concentrations decreased C_m to similar levels as in the presence of neutral buffers. …”

Regulatory T cell suppressive function. by Joost Smolders (235367)

“…Co-culture with an increasing proportion of Treg results in an inhibition of Tresp cell proliferation (downward panels, ratio 0.25∶1, 0.5∶1, 1∶1 and 2∶1, respectively). An increasing proportion of CFSE⁻ Treg can be observed, and a subsequent decrease of proliferating CFSE⁺ Tresp cells. …”

Conservation of crisp lettuce in different post-harvest storage conditions by Mariana Izabel Schvambach (10371895)

“…There was a decrease in the parameters of fresh mass, acidity, total soluble solids, and relative content of SPAD chlorophyll in refrigerated lettuce compared to uncooled. …”

Disturbed zinc and ZIP8 homeostasis. by Eung-Kwon Pae (374276)

“…Scale bars indicate 5 µm. (E and F) Zinc taken up by the beta cells decreased in the IH group, yet not as much as the amount decreased in the siZIP8 treated cells (F). …”

α-flupentixol induces hypomotor activity and catalepsy. by Jonathan Chetrit (371852)

“…<p>(A–C) Histograms illustrating the scored motor activity recorded during the second 10 minutes session fifty minutes after the injection of saline (control) or α-flupentixol (0.3 mg/kg) or saline on day 4, 5 and 6 respectively. …”

Effect of IL-6 on Caco-2 tight junction proteins expression. by Rana Al-Sadi (541571)

“…<p>(A) IL-6 caused a time-dependent increase in claudin-2 protein expression but not claudins 3, 5, and 8 as assessed by Western Blot analysis. …”

Marimastat reversed hepatic steatosis and improved surrogate markers for insulin sensitivity in diet-induced obese mice as well as in <i>ob/ob</i> animals. by Vincent E. de Meijer (343377)

“…<p>Mean hepatic fat fraction as measured by MR spectroscopy was decreased following Marimastat treatment (A). Marimastat treatment resulted in a decrease of plasma alanine aminotransferase levels (B), indicating decreased hepatic injury. …”

Corn crop evolution. by Luis García-Torres (5662132)

“…<p>A: late May and early June, corn during the vegetative growing phase, characterized by increasing NDVI values and coinciding with the T3–T4 satellite images of this stage; B: flowering stage, July, T5 image; C: senescence period, which take place in the second part of August (NDVI values decrease; satellite image T6); and D: corn stubble, beyond mid-September (satellite image T7). …”

Floral organ numbers in “Malmaison” and “St Anne's”. by Annick Dubois (19875)

“…The two rose varieties differ in two floral characters: organ identity reversions from petals in “Malmaison” to stamens in “St Anne's” and an overall decrease in total organ number. Chimeras: staminoid petals (see <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0009288#pone.0009288.s002" target="_blank">Figure S1</a>). …”

Foxd1DTA mutants have cortical regions devoid of nephron progenitor caps and ureteric branching defects. by Stephanie Hum (520223)

“…<p>A–B: Six2 immunofluorescence staining showed that mutant kidneys (B) had gaps in Six2 expression in the renal cortex compared to the consistent line of nephron progenitor caps in controls (A). …”

RanGAP1 knockdown inhibited the expression of Aurora kinases and TPX2, but did not affect their transcription. by Kung-Chao Chang (170593)

“…(<b>B</b>) Q-PCR shows no significant (NS) decrease in mRNA level of Aurora-A and Aurora-B kinases in DLBCL cells, HT cells (upper panel), or SU-DHL-5 cells (lower panel). …”

Mortality by suicide in the State of Pernambuco, Brazil (1996-2015) by Barbara Marcela Beringuel (10369083)

“…The temporal trend presented a decrease of 23.5% (p=0.031). For the male sex and the age range between 20 and 39 years, there was a decline in self-inflicted death of 23.8% (p=0.018) and 26.1% (p=0.046), respectively. …”

Biochemical analysis of synaptophysin levels in transgenic mice. by Holly J. Garringer (281855)

“…No significant changes were observed at 3 months of age in synaptophysin levels between Tg-FDD-Tau and WT mice (A). A significant decrease in synaptophysin levels in Tg-FDD-Tau mice is observed at 6 months of age (B). …”

Potential mechanisms for the reducing BRCA1 expression by Christopher R Mueller (1657)

“…Methylation of both promoters through an unidentified mechanism would lead to a dramatic decrease in expression. Increased NBR2 expression could lead to decreased BRCA1 expression. p53 could inhibit factors such as E2F. …”

Relative quantities (RQ) of <i>amTOR</i> mRNA levels in honey bee larvae. by Avani Patel (30611)

“…<p>In colonies a–b, queen- (Q) and worker-destined (W) larvae are characterised by a transient two-fold difference in <i>amTOR</i> expression (present in 3^rd instar larvae, absent in spinning 5^th instar larvae). …”