Showing 1,281 - 1,300 results of 100,788 for search '(( 5 ((026 decrease) OR (a decrease)) ) OR ( 5 ((we decrease) OR (nn decrease)) ))', query time: 1.57s Refine Results
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    Design, Synthesis, and Biological Evaluation of [1,2,5]Oxadiazolo[3,4‑<i>b</i>]pyridin-7-ol as Mitochondrial Uncouplers for the Treatment of Obesity and Metabolic Dysfunction-Assoc... by Mary A. Foutz (20361830)

    Published 2024
    “…Mitochondrial uncouplers such as BAM15 increase respiration and energy expenditure and have potential in treating a variety of metabolic diseases. In this study, we disclose the structure–activity relationship profile of 6-substituted [1,2,5]oxadiazolo[3,4-<i>b</i>]pyridin-7-ol derivatives of BAM15. …”
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    MicroRNA expression profile in retina and choroid in oxygen-induced retinopathy model by Michel Desjarlais (6832442)

    Published 2019
    “…During OIR-induced vessel degeneration phase, miR-199a-3p, -199a-5p, -1b, -126a-3p displayed a robust decreased expression (> 85%) in the retina. …”
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    FLIM-FRET measurements with KIRIN1 sensor detects relative changes in intracellular K<sup>+</sup>. by Xiaowen Jiang (8291814)

    Published 2024
    “…<b>(C)</b> FLIM-FRET measurements for intracellular K<sup>+</sup> levels in HEK293 Cells transfected with the CMV:KIRIN1 sensor and either CMV:Kcnk5bS345A-mCherry, CMV:Kcnk5bWT-mCherry, or CMV:Kcnk5bS345E-mCherry. …”
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    Treatment adoption and diffusion pattern. by Frédéric Galacteros (11105678)

    Published 2023
    “…In clinical studies, voxelotor has been shown to increase hemoglobin (Hb) and decrease hemolytic markers in patients with SCD. The objective of this study was to estimate the impact of voxelotor on the burden of SCD in France using a modeling approach, accounting for its anticipated adoption and diffusion over the next 5 years. …”
  12. 1292

    pH Dependence of Succinimide-Ester-Based Protein Cross-Linking for Structural Mass Spectrometry Applications by Esben Trabjerg (1540687)

    Published 2021
    “…The applicability of lysine-reactive cross-linking reagents to low-pH conditions remains unclear. Here, we cross-linked a mixture of eight model proteins at eight different pH conditions (pH 4.0–7.5) to investigate the pH dependency of DSS. …”
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    Cardiac Development in Zebrafish and Human Embryonic Stem Cells Is Inhibited by Exposure to Tobacco Cigarettes and E-Cigarettes by Nathan J. Palpant (127912)

    Published 2015
    “…During cardiac differentiation of hESCs, tobacco smoke exposure results in a delayed transition through mesoderm. Both types of cigarettes decrease expression of cardiac transcription factors in cardiac progenitor cells, suggesting a persistent delay in differentiation. …”
  17. 1297

    Table_1_Unconventional Sea Surface Temperature Regime Around Japan in the 2000s–2010s: Potential Influences on Major Fisheries Resources.docx by Hiroshi Kuroda (769431)

    Published 2020
    “…In this paper, we review atmosphere and ocean conditions around Japan in the 2000s–2010s in terms of global climate, present an overview of potential impacts of decadal SST trends on five major commercial fisheries resources (walleye pollock, chum salmon, Japanese sardine, Japanese anchovy, and Japanese flying squid), and raise awareness that an unconventional regime can appear transiently during a state of global warming.…”
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    Molecular insights in the pathogenesis of classical Ehlers-Danlos syndrome from transcriptome-wide expression profiling of patients’ skin fibroblasts by Nicola Chiarelli (756982)

    Published 2019
    “…<div><p>Classical Ehlers-Danlos syndrome (cEDS) is a dominant inherited connective tissue disorder mainly caused by mutations in the <i>COL5A1</i> and <i>COL5A2</i> genes encoding type V collagen (COLLV), which is a fibrillar COLL widely distributed in a variety of connective tissues. cEDS patients suffer from skin hyperextensibility, abnormal wound healing/atrophic scars, and joint hypermobility. …”
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    a-c: Bone marrow (BM) EPO receptor (EPO-R) decreases in uremic anemia rats. by Daniel Landau (440830)

    Published 2018
    “…<p>BM EPO-R protein (depicted as percentage of actin-corrected concentration) is unchanged in 7 day-bled rats Vs controls (Fig. 4a). Contrary to that BM EPO-R protein decreases in uremic (4 weeks after 5/6 nephrectomy) rats (Fig. 4b). …”