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026 decrease » _ decrease (Expand Search), nn decrease (Expand Search)
a decrease » _ decrease (Expand Search), _ decreased (Expand Search), _ decreases (Expand Search)
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Excess glucose availability negatively impacts healthspan of young and old animals; conversely, the benefits of disrupting glycolysis do not include extended maximal lifespan.
Published 2020“…Exposure to excess glucose results in significant decreases in swimming rates in young animals (day 5 from hatching; <i>P</i> = 0.0004, unpaired t test). n = 40 animals per condition from a single trial; error bars represent SEM; *** <i>P</i> < 0.001. …”
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Human AQP5 Plays a Role in the Progression of Chronic Myelogenous Leukemia (CML)
Published 2008“…Furthermore, our findings may provide the basis for a novel CML therapy targeting AQP5.</p></div>…”
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15452
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A photomicrograph of sections of the ovary in different groups [Masson’s trichrome x100].
Published 2025“…Data are analyzed by one-way ANOVA and Bonferroni post hoc test at P < 0.05 and presented as mean ±SE. [a] versus the control group, [b] versus the P. dioscoridis group, and [c] versus the PCOS group.…”
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15456
Dietary Restriction Induces Gluconeogenic Gene <i>pck-2</i> Expression via DAF-16, and <i>pck-2</i> Expression is Needed for DR-associated Healthspan Benefits.
Published 2020“…Disrupting glycolytic activity with <i>pfk(RNAi)</i> results in small but significant increases in swimming rates early in life (day 5; <i>P</i> < 0.01, one way ANOVA, a 12% increase) and no later change; glycolytic gene <i>pyk-2(RNAi)</i> did not significantly affect swimming ability on any tested day. …”
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A Novel TGR5 Activator WB403 Promotes GLP-1 Secretion and Preserves Pancreatic β-Cells in Type 2 Diabetic Mice
Published 2015“…As a result, WB403 exhibited a moderate TGR5 activation effect while promoting GLP-1 secretion efficiently. …”
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15459
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15460