Table5_Orally Administered Probiotics Decrease Aggregatibacter actinomycetemcomitans but Not Other Periodontal Pathogenic Bacteria Counts in the Oral Cavity: A Systematic Review and Meta-Analysis.DOCX by Thanyaporn Sang-Ngoen (11241888)

Image5_Orally Administered Probiotics Decrease Aggregatibacter actinomycetemcomitans but Not Other Periodontal Pathogenic Bacteria Counts in the Oral Cavity: A Systematic Review and Meta-Analysis.TIF by Thanyaporn Sang-Ngoen (11241888)

Functional validation of a miRNA-34a-TREM2–3’UTR interaction. by Surjyadipta Bhattacharjee (3181674)

“…<p><b>(A)</b> ribonucleotide sequence of the 299 nt TREM2-mRNA-3’-UTR is shown in the 5’-3’ direction; the 22 nt miRNA-34a-TREM2 3’UTR complementarity-interaction region is indicated by a black underline and the 8 nt TREM2-mRNA-3’-UTR seed sequence <b>5’-ACACUGCU-3’</b> is overlaid in yellow; a single arrowhead indicates the 5’ end of a poly A+ tail in the TREM2 mRNA (22 ‘A’ nt shown; the length of this poly A+ tail is variable); TREM2 mRNA sequence derived from NM_018965; TREM2 transcript is the major X1 variant (see also <a href="http://switchdb.switchgeargenomics.com/productinfo/id_801321/" target="_blank">http://switchdb.switchgeargenomics.com/productinfo/id_801321/</a>) (<b><a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.g003" target="_blank">Fig 3</a></b>); <b>(B)</b> TREM2-mRNA-3’UTR expression vector luciferase reporter assay (pLightSwitch-3’UTR; Cat#S801178; Switchgear Genomics, Palo Alto CA); in this vector, the entire 299 nucleotide TREM2 3’UTR was ligated into the unique Nhe1-Xho1 site; <b>(C)</b> control C8B4 murine microglial cells, 1 week in culture; phase contrast bright field microscopy 20x; C8B4 cells transfected with the TREM2-mRNA-3’UTR expression vector luciferase reporter were treated exogenously with miRNA-34a, a scrambled control miRNA-34a (miRNA-sc) or control miRNA-183; see references and text for further details [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.ref018" target="_blank">18</a>,<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0150211#pone.0150211.ref019" target="_blank">19</a>]; <b>(D)</b> compared to control, C8B4 cells transfected with a scrambled (<b>sc</b>) control pLightSwitch-3’UTR vector, the TREM2-mRNA-3‘UTR vector exhibited decreased luciferase signal to a mean of 0.16-fold of controls in the presence of miRNA-34a; this same vector exhibited no change in the presence of the control miRNA-34a-sc or miRNA-183; for each experiment (using different batches of MG cells) a control luciferase signal was generated and included separate appropriate controls with each analysis; in addition a control vector β-actin-3’UTR showed no significant effects on the relative luciferase signal yield after treatment with either miRNA-183 or miRNA-34a (data not shown); dashed horizontal line set to 1.0 for ease of comparison; N = 5; *<i>p</i><0.001 (ANOVA). …”

Retigabine and ML213 decrease the constriction tone of human detrusor strips. by Julie Svalø (693320)

“…<p>(A) The original DSM tension recordings illustrate the relaxatory effect of retigabine and ML213, which are K_v7.2–7.5 and K_v7.2/7.4/7.5 channel activators, respectively. …”

Fig 5 - by Mary J. Obayemi (11813022)

Fig 5 - by Minhyeok Heo (12368513)

Changes in neural activity were decreased in animals pre-exposed to 5-HT and <i>mod-1</i> mutants when the worms switched their locomotive direction. by Haruka Mori (8082215)

“…<p>(A–F) the neural activity of the RID changes during the transition periods from backward to forward locomotion (A–C) and from forward to backward locomotion (D–F) in the mock (A: p = 1.5 × 10⁻⁵; D: p = 5.5 × 10⁻¹³), 5-HT exposed (B: p = 0.092; E: p = 0.79), and <i>mod-1</i> mutant (C: p = 0.081; F: p = 0.93) groups. …”

The black rim increases with decreasing spatial resolution between A and B by Lars Grosse-Wortmann (49974)

IL-4 up-regulated DEGs identified by RRA and fold-change analysis. by Giorgia Colombo (6337118)

Generation of influenza A viruses with decreased sensitivity to IFN-λ1. by Natalia A. Ilyushina (44418)

Neudesin: a neuropeptide hormone decreased in subjects with polycystic ovary syndrome by Giray Bozkaya (8739405)

Glucagon resistance and decreased susceptibility to diabetes in a model of chronic hyperglucagonemia by Nadejda Bozadjieva Kramer (9657179)

Increased endodiastolic volume and decreased ejection fraction in GJB4-deficient zebrafish. by Ryuji Okamoto (614374)

B-factor values of Ca_V3.3 M1425 substitutions. by Yousra El Ghaleb (22075892)

Subjects:

Amino acids 605 and 606 of the PB2 ‘627’ domain are involved in interaction with NP. by Ho-Pan Hsia (4768638)

Forward and reverse primer sequences 5´-3´ used in the study. by Mohamad Karaky (8910497)

Subjects:

A comparison of fold-change of taxa found in ambulances relative to first sampling event. by Taylor Sheahan (7037267)

“…Yellow squares correspond to an increase in a given taxa at a corresponding week relative to Week 1, while blue squares indicate a decrease in abundance of a taxa relative to Week 1. …”

Stigma and health-related quality of life (HRQoL) in multi-drug-resistant tuberculosis (MDR-TB) outpatient in Indonesia: A cross-sectional study by Bustanul Arifin (20360859)

IL-8 secretion decreased from TLR5 silenced (siRNA) Caco-2BBe cells exposed to flagellin. by Tonyia Eaves-Pyles (344135)

“…<p><b>A. </b><i>S. dublin</i> flagellin was added to the AP or BL surface of polarized Caco-2BBe cells where TLR5 was knocked down using siRNA. …”

The substitution F447L is adaptive for J4_S52-HVR1, while it decreases infectivity of parental J4 and J4_ΔHVR1 HCVcc. by Christina Holmboe Olesen (11154333)