Nitric Oxide Oxidatively Nitrosylates Ni(I) and Cu(I) <i>C</i>-Organonitroso Adducts by Stefan Wiese (1626535)

“…[Me₂NN]Cu(NCMe) reacts with 0.5 equiv of ArNO in ether to give the dinuclear adducts {[Me₂NN]Cu}₂(μ-η²:η¹-ONAr) (<b>2a</b> and <b>2b</b>), which exhibit η² and η¹ bonding of the ArNO moiety with separate [Me₂NN]Cu fragments possessing N−O distances of 1.375(6) Å (<b>2a</b>) and 1.368(2) Å (<b>2b</b>). …”

Nitric Oxide Oxidatively Nitrosylates Ni(I) and Cu(I) <i>C</i>-Organonitroso Adducts by Stefan Wiese (1626535)

“…[Me₂NN]Cu(NCMe) reacts with 0.5 equiv of ArNO in ether to give the dinuclear adducts {[Me₂NN]Cu}₂(μ-η²:η¹-ONAr) (<b>2a</b> and <b>2b</b>), which exhibit η² and η¹ bonding of the ArNO moiety with separate [Me₂NN]Cu fragments possessing N−O distances of 1.375(6) Å (<b>2a</b>) and 1.368(2) Å (<b>2b</b>). …”

Nitric Oxide Oxidatively Nitrosylates Ni(I) and Cu(I) <i>C</i>-Organonitroso Adducts by Stefan Wiese (1626535)

“…[Me₂NN]Cu(NCMe) reacts with 0.5 equiv of ArNO in ether to give the dinuclear adducts {[Me₂NN]Cu}₂(μ-η²:η¹-ONAr) (<b>2a</b> and <b>2b</b>), which exhibit η² and η¹ bonding of the ArNO moiety with separate [Me₂NN]Cu fragments possessing N−O distances of 1.375(6) Å (<b>2a</b>) and 1.368(2) Å (<b>2b</b>). …”

Video_5_Analog Models of Fold-and-Thrust Wedges in Progressive Arcs: A Comparison With the Gibraltar Arc External Wedge.MP4 by Alejandro Jiménez-Bonilla (8639379)

“…We present laboratory models of fold-and-thrust belts formed with a backstop that deforms in map view to simulate progressive arcs in a thin-skinned tectonic regime. …”

Albumin Decrease Is Associated with Spontaneous Preterm Delivery within 48 h in Women with Threatened Preterm Labor by Yujing J. Heng (1696339)

“…SWATH methodology quantified 258 proteins (using ≥2 peptides) and 5 proteins (ALBU, ANXA6, HNRPK, HSP90A, and PDIA1) were differentially expressed (<i>p</i> < 0.05, Mann–Whitney <i>U</i>). iTRAQ workflow identified 765 proteins; 354 proteins were quantified and 14 proteins (MIF, UBIQ, HXK3, ALBU, HNRPD, ST1A2, RS15A, RAP1B, CAN1, IQGA2, ST1A1, COX5A, ADDA, and UBQL1) were significantly different between the two groups of women (<i>p</i> < 0.05, Mann–Whitney <i>U</i>). …”

Albumin Decrease Is Associated with Spontaneous Preterm Delivery within 48 h in Women with Threatened Preterm Labor by Yujing J. Heng (1696339)

“…SWATH methodology quantified 258 proteins (using ≥2 peptides) and 5 proteins (ALBU, ANXA6, HNRPK, HSP90A, and PDIA1) were differentially expressed (<i>p</i> < 0.05, Mann–Whitney <i>U</i>). iTRAQ workflow identified 765 proteins; 354 proteins were quantified and 14 proteins (MIF, UBIQ, HXK3, ALBU, HNRPD, ST1A2, RS15A, RAP1B, CAN1, IQGA2, ST1A1, COX5A, ADDA, and UBQL1) were significantly different between the two groups of women (<i>p</i> < 0.05, Mann–Whitney <i>U</i>). …”

Intravitreal ALF-186 decreased the IRI-induced capsase-3 and NF-κB mRNA expression and affected the heat-shock response differently. by Julia Stifter (4621033)

“…<p><b>(A)</b> Fold induction of caspase-3 mRNA expression after PBS, ALF-186, or iALF injection after IRI compared to GAPDH in relation to the corresponding non-ischemic contralateral retina analyzed by RT-PCR (n = 6; mean±SD; *** = p<0.001; *** = p<0.001). …”

Emission spectra of S100A1 fluorescence titrations exhibiting decreasing fluorescence intensities with increasing concentration of S100B at the μM level. by Md. Imran Khan (4853302)

Effect of exogenous ERα expression on the ability of Wnt-5a to decrease breast cancer cell invasion. by Janna Sand-Dejmek (449584)

R848 mediated RANTES, but not TNF-α production, is significantly decreased in TRAM^−/− iBMDMs. by Enda Shevlin (628477)

The 10 most highly regulated genes in sputum and blood from microarray analysis; a positive fold change  =  increase in frequent exacerbators compared to zero exacerbators, a negative fold change  =  decrease in frequent exacerbators compared to zero exacerbators. by Dave Singh (114223)

“…</p><p>The 10 most highly regulated genes in sputum and blood from microarray analysis; a positive fold change  =  increase in frequent exacerbators compared to zero exacerbators, a negative fold change  =  decrease in frequent exacerbators compared to zero exacerbators.…”

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

“…Compound <b>4f</b> exhibited potent EGFR inhibitory activity with an IC₅₀ value of 61 nM compared to that of Tamoxifen (IC₅₀ value of 69 nM), with EGFR inhibition of 83 and 84%, respectively, at a concentration of 10 μM. Interestingly, <b>4f</b> showed remarkable PI3K/AKT/mTOR inhibitory activity with 0.18-, 0.27-, and 0.39-fold decrease in their concentration (reduction in controls from 6.64, 45.39, and 86.39 ng/mL to 1.24, 12.35, and 34.36 ng/mL, respectively). …”

Synthesis and Antiproliferative Activity of a New Series of Mono- and Bis(dimethylpyrazolyl)‑<i>s</i>‑triazine Derivatives Targeting EGFR/PI3K/AKT/mTOR Signaling Cascades by Ihab Shawish (13015516)

“…Compound <b>4f</b> exhibited potent EGFR inhibitory activity with an IC₅₀ value of 61 nM compared to that of Tamoxifen (IC₅₀ value of 69 nM), with EGFR inhibition of 83 and 84%, respectively, at a concentration of 10 μM. Interestingly, <b>4f</b> showed remarkable PI3K/AKT/mTOR inhibitory activity with 0.18-, 0.27-, and 0.39-fold decrease in their concentration (reduction in controls from 6.64, 45.39, and 86.39 ng/mL to 1.24, 12.35, and 34.36 ng/mL, respectively). …”

DnaK inhibits protein synthesis in vivo and in vitro. by Carissa Chan (18310140)

DnaK’s ATPase activity is stimulated by ribosomes and required to reduce protein synthesis. by Carissa Chan (18310140)

DnaK associates with intact ribosomes and not with dismantled ribosomes. by Carissa Chan (18310140)

GFP activity is decreased in DES. by Céline Portal (3876436)

“…AB—PAS and serial immunohistochemical section of the left eye, which received PBS, and paired-right eye which received BAK show a decrease in the number of conjunctival goblet cells producing Muc5b (blue arrows) and non-Muc5b producing (white arrows) cells. …”

Trigger factor hinders DnaK-mediated reduction of protein synthesis. by Carissa Chan (18310140)

Preparations of DnaK protein are pure. by Carissa Chan (18310140)

DnaK does not refold heat-denatured luciferase when incubated in the presence of ribosomes. by Carissa Chan (18310140)