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Molecular insights in the pathogenesis of classical Ehlers-Danlos syndrome from transcriptome-wide expression profiling of patients’ skin fibroblasts
Published 2019“…<div><p>Classical Ehlers-Danlos syndrome (cEDS) is a dominant inherited connective tissue disorder mainly caused by mutations in the <i>COL5A1</i> and <i>COL5A2</i> genes encoding type V collagen (COLLV), which is a fibrillar COLL widely distributed in a variety of connective tissues. cEDS patients suffer from skin hyperextensibility, abnormal wound healing/atrophic scars, and joint hypermobility. …”
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A Peptide Mimetic of 5-Acetylneuraminic Acid-Galactose Binds with High Avidity to Siglecs and NKG2D
Published 2015“…Using plant lectins as analogs of lectin-type cell-surface receptors, a tetravalent form of a peptide with the sequence NPSHPLSG, designated svH1C, bound with high avidity to lectins specific for glycans with terminal 5-acetylneuraminic acid (Neu5Ac)-galactose (Gal)/N-acetylgalactosamine (GalNAc) sequences. …”
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R346K Mutation in the <i>Mu</i> Variant of SARS-CoV‑2 Alters the Interactions with Monoclonal Antibodies from Class 2: A Free Energy Perturbation Study
Published 2022“…The <i>Mu</i> variant of SARS-CoV-2 has been recently classified as a variant of interest (VOI) by the World Health Organization (WHO) but limited data are available at the moment. …”
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R346K Mutation in the <i>Mu</i> Variant of SARS-CoV‑2 Alters the Interactions with Monoclonal Antibodies from Class 2: A Free Energy Perturbation Study
Published 2022“…The <i>Mu</i> variant of SARS-CoV-2 has been recently classified as a variant of interest (VOI) by the World Health Organization (WHO) but limited data are available at the moment. …”
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Optical Control of Insect Behavior and Receptors with Azobenzene-Bridged Fipronil and Imidacloprid
Published 2024“…IMI-AB-FIP in both <i>trans</i>/<i>cis</i> isomers can be reversibly interconverted depending on light, accompanied by insecticidal activity decrease or increase by 1.5–2.3 folds. In addition, IMI-AB-FIP displayed synergistic effects against A. craccivora (LC<sub>50, IMI‑AB‑FIP</sub> = 14.84–22.10 μM, LC<sub>50, IMI‑AB‑IMI</sub> = 210.52–266.63 μM, LC<sub>50, and FIP‑AB‑FIP</sub> = 36.25–51.04 μM), mainly resulting from a conceivable reason for simultaneous targeting on both GABARs and nAChRs. …”
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Image_1_IL-1β enhances cell viability and decreases 5-FU sensitivity in novel colon cancer cell lines derived from African American patients.tif
Published 2022“…A significant decrease in the response to 5-FU treatment, as well as a significant increase in phosphorylation of IκBα and secretion of IL-8, was seen following IL-1β treatment, in both AA and CA cell lines. …”
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Image_2_IL-1β enhances cell viability and decreases 5-FU sensitivity in novel colon cancer cell lines derived from African American patients.tif
Published 2022“…A significant decrease in the response to 5-FU treatment, as well as a significant increase in phosphorylation of IκBα and secretion of IL-8, was seen following IL-1β treatment, in both AA and CA cell lines. …”
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Complete data.
Published 2024“…A tenfold decrease or increase in concentration induced only a 2-fold decrease or increase in clot degradation. …”
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Fig 4 -
Published 2024“…A tenfold decrease or increase in concentration induced only a 2-fold decrease or increase in clot degradation. …”
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