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74541
DataSheet2_Chinese Herbal Extracts Exert Neuroprotective Effect in Alzheimer’s Disease Mouse Through the Dopaminergic Synapse/Apoptosis Signaling Pathway.ZIP
Published 2022“…<p>Background: Alzheimer’s disease (AD) as an age-related, irreversible neurodegenerative disease, characterized by cognitive dysfunction, has become progressively serious with a global rise in life expectancy. As the failure of drug elaboration, considerable research effort has been devoted to developing therapeutic strategies for treating AD. …”
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74542
DataSheet1_Chinese Herbal Extracts Exert Neuroprotective Effect in Alzheimer’s Disease Mouse Through the Dopaminergic Synapse/Apoptosis Signaling Pathway.PDF
Published 2022“…<p>Background: Alzheimer’s disease (AD) as an age-related, irreversible neurodegenerative disease, characterized by cognitive dysfunction, has become progressively serious with a global rise in life expectancy. As the failure of drug elaboration, considerable research effort has been devoted to developing therapeutic strategies for treating AD. …”
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74543
DataSheet3_Chinese Herbal Extracts Exert Neuroprotective Effect in Alzheimer’s Disease Mouse Through the Dopaminergic Synapse/Apoptosis Signaling Pathway.ZIP
Published 2022“…<p>Background: Alzheimer’s disease (AD) as an age-related, irreversible neurodegenerative disease, characterized by cognitive dysfunction, has become progressively serious with a global rise in life expectancy. As the failure of drug elaboration, considerable research effort has been devoted to developing therapeutic strategies for treating AD. …”
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74544
Glatiramer Acetate (Copaxone) Modulates Platelet Activation and Inhibits Thrombin-Induced Calcium Influx: Possible Role of Copaxone in Targeting Platelets during Autoimmune Neuroin...
Published 2014“…We found that GA inhibited thrombin-induced calcium influx in human and mouse platelets. GA also decreased thrombin-induced CD31, CD62P, CD63, and active form of αIIbβ3 integrin surface expression and formation of platelet aggregates for both mouse and human platelets, and prolonged the bleeding time in mice by 2.7-fold. …”
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74545
Overexpression of Catalase Diminishes Oxidative Cysteine Modifications of Cardiac Proteins
Published 2015“…Catalase overexpression globally decreased thiol occupancy by ≥1.3 fold in 82 proteins, including numerous mitochondrial and contractile proteins. …”
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74546
Pi transporters in human valve interstitial cells (VICs).
Published 2013“…</b> Following exposure to Pi, VICs have increased expression of SLC20A1 and SLC20A2 transcripts by several folds, with the highest magnitude for SLC20A1 (results expressed in function of SLC20A2 as the referent) (SLC20A1 increased by 5.3-folds when compared to SLC20A2) <b>C</b>. …”
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74547
File S1 - Impaired Functionality of Antiviral T Cells in G-CSF Mobilized Stem Cell Donors: Implications for the Selection of CTL Donor
Published 2013“…After 48 h of storage at 4°C, a mean of 93% (mCMV_pp65_A02, n = 4) and 96% (mCMV_pp65_B07, n = 5) of the frequency in the fresh sample (baseline) was obtained. …”
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74548
Involvement of SKN-1 in immunosenescence.
Published 2012“…<p>(<b>A</b>) Representative epifluorescence images showing the decreased induction of the <i>gcs-1</i> promoter. …”
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74549
Biological experiments using human CRC cell lines show feedback regulation of progenitor NECs occurs via mature GLP-2R+ and SSTR1+ NECs.
Published 2020“…To investigate paracrine signaling influence of NECs on ALDH+ cells, we studied the effect of CM from GLP-2R+ or from SSTR1+ cells on ALDEFLOUR+ cells isolated from the HT29 cell line. There was a significant decrease in the number of ALDEFLOUR+ cells grown in GLP-2R+ CM, but not SSTR1+ CM. …”
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74550
Unexpected Selectivities in C−H Activations of Toluene and <i>p</i>-Xylene at Cationic Platinum(II) Diimine Complexes. New Mechanistic Insight into Product-Determining Factors
Published 2001“…The elimination of toluene from (N<sup>f</sup>N<sup>f</sup>)Pt(Tol)<sub>2</sub> species (<b>3a</b>−<b>c</b>; <b>a</b>, Tol = <i>o</i>-tolyl; <b>b</b>, Tol = <i>m</i>-tolyl;<b> c</b>, Tol = <i>p</i>-tolyl) after protonolysis with 1 equiv of HBF<sub>4</sub> was investigated. …”
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74551
Hierarchical clustering analysis of the expression of 390 miRNAs obtained from whole embryos of E9
Published 2011“…All rights reserved</p>5, E10.5 and E11.5. () Heatmap and dendrogram (a tree graph). …”
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74552
Long term PFC accumulation and correlation to viral tumor load.
Published 2013“…(<b>D</b>) quantitative evaluation of the <sup>19</sup>FTVR decrease (7 to 11 dpi) of mock-infected and GLV-1h68-treated 1936-MEL tumors during the time course study measured by <i>in vivo </i><sup>19</sup>F MRI revealed a significant difference between both groups (n = 4; p = 0.038). …”
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74553
Triterpene acid- and lectin-containing extracts induce apoptosis in leukaemia cells.
Published 2015“…<p><b>A.</b> To measure the induction of apoptosis by VAE, U937 and HL-60 cells were treated with different concentrations of the extracts for 18 h. …”
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74554
Data_Sheet_1_Coordinated Reset Vibrotactile Stimulation Induces Sustained Cumulative Benefits in Parkinson’s Disease.pdf
Published 2021“…EEG recordings observed from study 1 indicated a significant decrease in off-medication cortical sensorimotor high beta power (21—30 Hz) at rest after 3 months of daily noisy vCR therapy. …”
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74555
Video_2_Coordinated Reset Vibrotactile Stimulation Induces Sustained Cumulative Benefits in Parkinson’s Disease.mp4
Published 2021“…EEG recordings observed from study 1 indicated a significant decrease in off-medication cortical sensorimotor high beta power (21—30 Hz) at rest after 3 months of daily noisy vCR therapy. …”
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74556
Video_1_Coordinated Reset Vibrotactile Stimulation Induces Sustained Cumulative Benefits in Parkinson’s Disease.MP4
Published 2021“…EEG recordings observed from study 1 indicated a significant decrease in off-medication cortical sensorimotor high beta power (21—30 Hz) at rest after 3 months of daily noisy vCR therapy. …”
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74557
FOXM1 directly binds to and induces transcriptional activity of <i>Dusp1</i> promoter in macrophages.
Published 2020“…<p><b>(A)</b> Depletion of <i>Foxm1</i> in macrophages decreased <i>Dusp1</i> mRNA and increased <i>Tnf</i>, <i>Il6</i> and <i>Il1b</i> mRNA. …”
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74558
WV phase space projection for QIF model with spike waveform, and convergent iterative theoretical predictions for <i>μ</i> > <i>μ</i>* and <i>μ</i> → 0.
Published 2016“…Inset shows the cyan trajectory in terms of decaying variables <i>x</i>*(<i>t</i>) and <i>C</i>*(<i>t</i>), and how <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0159300#pone.0159300.e084" target="_blank">Eq (22)</a> captures the initial increase and then decrease in the calcium concentration, while <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0159300#pone.0159300.e083" target="_blank">Eq (21)</a> does not. …”
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74559
Long-term cultivation of MSCs alters their mitochondrial function.
Published 2012“…(<b>C</b>): The total antioxidant capacity decreases with increasing passage number. Moreover, yMSCs of P2 and P100 exhibited significant higher antioxidant activities than aMSCs of the same passage. …”
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74560
The progression of cellular events that occurs in dystrophic mdx limb muscles.
Published 2014“…From 4 to 5 wk of age, myotubes form and damaged myofibers undergo regeneration <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0089277#pone.0089277-Evans2" target="_blank">[77]</a>. …”