Image_2_CC16 drives VLA-2-dependent SPLUNC1 expression.tiff by Natalie Iannuzo (4570714)

“…Short Palate Lung and Nasal Epithelial Clone 1 (SPLUNC1) was the most differentially expressed protein (66-fold) and was the focus of this study. Using a combination of MTECs and HNECs, we found that CC16 enhances pulmonary epithelial-driven SPLUNC1 expression via signaling through the receptor complex Very Late Antigen-2 (VLA-2) and that rCC16 given to mice enhances pulmonary SPLUNC1 production and decreases Mycoplasma pneumoniae (Mp) burden. …”

DataSheet_1_CC16 drives VLA-2-dependent SPLUNC1 expression.docx by Natalie Iannuzo (4570714)

“…Short Palate Lung and Nasal Epithelial Clone 1 (SPLUNC1) was the most differentially expressed protein (66-fold) and was the focus of this study. Using a combination of MTECs and HNECs, we found that CC16 enhances pulmonary epithelial-driven SPLUNC1 expression via signaling through the receptor complex Very Late Antigen-2 (VLA-2) and that rCC16 given to mice enhances pulmonary SPLUNC1 production and decreases Mycoplasma pneumoniae (Mp) burden. …”

Image_4_CC16 drives VLA-2-dependent SPLUNC1 expression.tiff by Natalie Iannuzo (4570714)

“…Short Palate Lung and Nasal Epithelial Clone 1 (SPLUNC1) was the most differentially expressed protein (66-fold) and was the focus of this study. Using a combination of MTECs and HNECs, we found that CC16 enhances pulmonary epithelial-driven SPLUNC1 expression via signaling through the receptor complex Very Late Antigen-2 (VLA-2) and that rCC16 given to mice enhances pulmonary SPLUNC1 production and decreases Mycoplasma pneumoniae (Mp) burden. …”

Image_1_CC16 drives VLA-2-dependent SPLUNC1 expression.tif by Natalie Iannuzo (4570714)

“…Short Palate Lung and Nasal Epithelial Clone 1 (SPLUNC1) was the most differentially expressed protein (66-fold) and was the focus of this study. Using a combination of MTECs and HNECs, we found that CC16 enhances pulmonary epithelial-driven SPLUNC1 expression via signaling through the receptor complex Very Late Antigen-2 (VLA-2) and that rCC16 given to mice enhances pulmonary SPLUNC1 production and decreases Mycoplasma pneumoniae (Mp) burden. …”

Image_3_CC16 drives VLA-2-dependent SPLUNC1 expression.tiff by Natalie Iannuzo (4570714)

“…Short Palate Lung and Nasal Epithelial Clone 1 (SPLUNC1) was the most differentially expressed protein (66-fold) and was the focus of this study. Using a combination of MTECs and HNECs, we found that CC16 enhances pulmonary epithelial-driven SPLUNC1 expression via signaling through the receptor complex Very Late Antigen-2 (VLA-2) and that rCC16 given to mice enhances pulmonary SPLUNC1 production and decreases Mycoplasma pneumoniae (Mp) burden. …”

Image_6_CC16 drives VLA-2-dependent SPLUNC1 expression.tif by Natalie Iannuzo (4570714)

“…Short Palate Lung and Nasal Epithelial Clone 1 (SPLUNC1) was the most differentially expressed protein (66-fold) and was the focus of this study. Using a combination of MTECs and HNECs, we found that CC16 enhances pulmonary epithelial-driven SPLUNC1 expression via signaling through the receptor complex Very Late Antigen-2 (VLA-2) and that rCC16 given to mice enhances pulmonary SPLUNC1 production and decreases Mycoplasma pneumoniae (Mp) burden. …”

Inhibition of ROCK with Y-27632 causes relaxation of rat mesenteric collecting lymphatics. by Kristine H. Kurtz (548350)

“…</i> AMP/MaxD significantly decreased with 5–50 μM Y-27632. <i>E.</i> Y-27632 (25–50 μM) significantly decreased lymphatic tone. …”

Data_Sheet_1_Genome-Wide Characterization of Ascorbate Peroxidase Gene Family in Peanut (Arachis hypogea L.) Revealed Their Crucial Role in Growth and Multiple Stress Tolerance.ZIP by Ali Raza (3558965)

“…<p>Ascorbate peroxidase (APX), an important antioxidant enzyme, plays a significant role in ROS scavenging by catalyzing the decrease of hydrogen peroxide under various environmental stresses. …”

Characterizing suboptimal child passenger safety practices in crashes with fatalities: Child, driver, vehicle, neighborhood, and policy factors by Arthi S. Kozhumam (14176683)

“…The strongest predictors of suboptimal practices were child age 4-7 years (OR 1.10, 95% CI 1.09-1.12) vs. <4 years and vehicle over capacity (OR 1.09, 95% CI 1.06-1.11). There was a decrease in suboptimal child passenger safety practices with increasing vehicle model year, COI level, fines, and law scores. …”

Data_Sheet_1_Genome-Wide Characterization of Ascorbate Peroxidase Gene Family in Peanut (Arachis hypogea L.) Revealed Their Crucial Role in Growth and Multiple Stress Tolerance.ZIP by Ali Raza (3558965)

“…<p>Ascorbate peroxidase (APX), an important antioxidant enzyme, plays a significant role in ROS scavenging by catalyzing the decrease of hydrogen peroxide under various environmental stresses. …”

Representative images and quantitative density of GATAs in paired tumor and peritumor tissues from consecutive sections of tissue microarray (40× and 200×). by Yi-Wei Li (441347)

“…<p>Expression of GATA2 (<b>A₅</b>) protein was decreased, GATA4 (<b>B₅</b>), GATA5 (<b>C₅</b>) and GATA6 (<b>D₅</b>) was increased in tumor tissues compared with adjacent liver tissues. …”

Reduced proliferative capacity and enhanced differentiation in FlnB knockdown proliferating chondrocytes. by Jianjun Hu (19574)

“…Alkaline phosphatase activity was decreased in FlnB knockdown ATDC5 cells. (D) FlnBsh2 chondrocytes undergo a slower growth rate compared to normal ATDC5 cells. …”

Dynamics of pressure buildup and release in plant extensor cells as calculated withEquation 4 and parameters based on literature values. by Brandon R. Bruhn (532763)

“…As a consequence, the influx of water leads to a decrease in <i>ΔΠ</i>.…”

DNMT inhibition induced cellular senescence. by Ah-Young So (221707)

“…(c–d) 5-AzaC increased p16^INK4A and p21^WAF1/Cip1 and decreased DNMT1, DNMT3A and DNMT3B, as shown by real-time qPCR analysis (c) and western blot analysis (d). 5-AzaC treatment for 1, 3, 5 and 7 days induced cellular senescence of hUCB-MSCs, as shown by SA β-gal staining (d). …”

Gene-chimeric co-culture of ventral hippocampus with nucleus accumbens. by Chongbo Zhong (493668)

“…<div><p><b>A</b>: Cultures of vHipp microslices from GFP reporter transgenic mice or WT mice (5-7 days <i>in </i><i>vitro</i>) were fixed, permeabilized, and stained with antibodies recognizing vGluT1 (red) and a panaxonal marker (SMI312, green) or a dendritic marker (MAP2, green). …”

The quality changes in fresh frozen plasma of the blood donors at high altitude by Zongkui Wang (3944837)

“…</p><p>Results</p><p>As compared with FFP of LA blood donors, the total protein content of HA blood donors showed a significant decrease (65.2±8.9 vs.57.2±6.3 g/L; p<i><</i>0.001); PT, aPTT, TT were significantly increased (p<i><</i>0.001); the levels of FII, FV, FVII, FVIII, FIX, FX, FXI, FXII and vWF:Ag were notably decreased (all p<i><</i>0.05), whereas Fbg and D-dimer were dramaticly increased (p = 0.038). …”

Quantitative structure–toxicity relationship models for predication of toxicity of ionic liquids toward leukemia rat cell line IPC-81 based on index of ideality of correlation by Shahin Ahmadi (9334861)

Other glycines substitutions that destabilize BH4-Bcl-2’s by Giovanni Monaco (452223)

Multiparametric <i>in vitro</i> genotoxicity assessment of different variants of amorphous silica nanomaterials in rat alveolar epithelial cells by Fátima Brandão (17222413)

GHG emissions along the baseline for different regions and sources by H Valin (557174)